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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CLCA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9635
Official gene symbolCLCA2
Full namechloride channel accessory 2
Aliases,CACC,CACC3,CLCRG2,CaCC-3,FLJ97885,
Gene summaryThe protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p31-p22
Gene position86889769 - 86922241  Map Viewer
Gene orientationplus
Gene size32473 bp
Gene sequence
OMIM ID604003