| Entrez gene ID | | 9620 |
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| Official gene symbol | | CELSR1 |
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| Full name | | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) |
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| Aliases | | ,CDHF9,DKFZp434P0729,FMI2,HFMI2,ME2, |
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| Gene summary | | The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq] |
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| Location | | Chromosome: 22 Locus: 22q13.3 |
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| Gene position | | 46933067 - 46756731 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 176337 bp |
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| Gene sequence |
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| OMIM ID | | 604523 |
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