Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LPXN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9404
Official gene symbolLPXN
Full nameleupaxin
Aliases,LDPL,
Gene summaryThe product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
LocationChromosome: 11   Locus: 11q12.1
Gene position58345639 - 58294344  Map Viewer
Gene orientationminus
Gene size51296 bp
Gene sequence
OMIM ID605390