| Entrez gene ID | | 9404 |
| Official gene symbol | | LPXN |
| Full name | | leupaxin |
| Aliases | | ,LDPL, |
| Gene summary | | The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Location | | Chromosome: 11 Locus: 11q12.1 |
| Gene position | | 58345639 - 58294344 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 51296 bp |
| Gene sequence |
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| OMIM ID | | 605390 |
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