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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NRXN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9379
Official gene symbolNRXN2
Full nameneurexin 2
Aliases,FLJ40892,KIAA0921,
Gene summaryThis gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).
LocationChromosome: 11   Locus: 11q13
Gene position64490660 - 64373646  Map Viewer
Gene orientationminus
Gene size117015 bp
Gene sequence
OMIM ID600566