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Gene information for NRXN3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9369
Official gene symbolNRXN3
Full nameneurexin 3
Aliases,C14orf60,KIAA0743,MGC176711,
Gene summaryNeurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two, NRXN1 and NRXN3, are among the largest known human genes. Three of the genes (NRXN1-3) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q31
Gene position78870093 - 80330762  Map Viewer
Gene orientationplus
Gene size1460670 bp
Gene sequence
OMIM ID600567