| Entrez gene ID | | 9282 |
| Official gene symbol | | MED14 |
| Full name | | mediator complex subunit 14 |
| Aliases | | ,CRSP150,CRSP2,CSRP,CXorf4,DRIP150,EXLM1,MGC104513,RGR1,TRAP170, |
| Gene summary | | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq] |
| Location | | Chromosome: X Locus: Xp11.4-p11.2 |
| Gene position | | 40594804 - 40508795 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 86010 bp |
| Gene sequence |
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| OMIM ID | | 300182 |
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