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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MED14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9282
Official gene symbolMED14
Full namemediator complex subunit 14
Aliases,CRSP150,CRSP2,CSRP,CXorf4,DRIP150,EXLM1,MGC104513,RGR1,TRAP170,
Gene summaryThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq]
LocationChromosome: X   Locus: Xp11.4-p11.2
Gene position40594804 - 40508795  Map Viewer
Gene orientationminus
Gene size86010 bp
Gene sequence
OMIM ID300182