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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBXN11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID91544
Official gene symbolUBXN11
Full nameUBX domain protein 11
Aliases,COA-1,DKFZp686F04228,PP2243,SOC,SOCI,UBXD5,
Gene summaryThis gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.11
Gene position26644756 - 26608773  Map Viewer
Gene orientationminus
Gene size35984 bp
Gene sequence
OMIM ID609151