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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GGTLC2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 91227 Official gene symbol GGTLC2 Full name gamma-glutamyltransferase light chain 2 Aliases ,GGTL4,MGC96916, Gene summary Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM] Location Chromosome: 22   Locus: 22q11.22 Gene position 22988782 - 22990368  Map Viewer Gene orientation plus Gene size 1587 bp Gene sequence >GGTLC2:2379351..2380937:Length=1587 GCCAGCTCTGGGGTCTCGGCAGGTGGTCCACAACATGACCTCTGAGTTCTTCGCTGCCCA GCTCCGGGCCCAGATCTCTGACGACACCACTCACCCGATCTCCTACTACAAGCCCGAGTT CTACACGCCGGTTGATGGGGGCACTGCTCACCTGTCTGTCGTCGCAGAGGACGGCAGTGC TGTGTCCGCCACCAGCACCATCAACCTCTAGTAGGGGCTGCTGGGCCGCCTGGGTGGGAA AGGGCCAGGGGCGGGTGGCCCAGGGACTGCCCACTTATCCAGTAAGGTGGCTCCATCACC TCTTTTCCTGGTGGGAAACTGAGGCCCAACCTTGGTAGCTTATCCTGGGCCTCTCAGTGA GTATGTTTGAGCCTCAGTGGGTGGATAGGGACCAGGCTGGGCCAGGCAAGGTCAGGTGCT GTCTGACCTGGCTGGGCGGTAGCTTTGGCTCCAAGGTCCGCTCCCCGGTCAGCGAGATCC TGTTCAATGATGAAATGGATGACTTCAGCTCTCCCAACATCACCAACGAGTTTGGGGTGC CCCCCTCACCTGCCAATTTCATCCAGCCAGGTATGGGGTGGAGGTCTGGGGATGGGGGAC TGGGGTGGAGAGGGGCGGGTGTCCTGGGCAGGCAGCTGACGGGCATCCCTGTCTTCTCCC ATCGGCCACAGGGAAGCAGCCGCTCTCGTCAATGTGCCCGACGATCATGGTGGGCCAGGA CGGCCAGGTCCGGATGGTGGTGGGAGCTGCTGGGGGCACACAGATCACCACAGCCACTGC ACTGATATGTGTCACCCCTTTTCTCCCTGGCCGTGCCCACCCTGCACAGCCCCCAAGCCA TGCTGATCACACTCCCATGCCCCAGGCCATCATCTACAACCTCTGGTTCGGCTATGACGT GAAGCGGGCCGTGGAGGAGCCCCGGCTGCACAACCAGCTTCTGCCCAACGTCACGACAGT GGAGAGAAACATTGACCAGGTGGGCCGGGGGTTGGAGAAACTGAGTCACGGTGTGGGGCC CCAGGGCATCCTGGGCTGGAGGCCTGGATCATCACAGAGTGGACAATTGTTGGTGTCCTC TCTCTAGTGCCTGGGCCATCTGGAGCCCCTGTGCCATGAGGGCCAAGCCCCCTGCTCCAG TGAGACCCAGCAGGCCCCAACCTGCTCTTCCTGATGACCTGGCCCGAAATGGCACCACCT GGGCTGAGGCCTGTGACCACACAGGTGTGGTTCAGGTGGCATCTGGAGCCCTGCTCAGGC TTCCCCTCTCCTCCCACCCCCAGGCAGTGACTGCAGCCCTGGAGACCCGGCACCATCACA CCCAGATCGCGTCCACCTTCATCGCTGTGGTGCAAGCCATCGTCCGCACGGCTGGTGGCT GGGCAGCTGCCTCGGACTCCAGGAAAGGCGGGGAGCCTGCCGGCTACTGAGTGCTCCAGG AGGACAAGGCTGACAAGCAATCCAGGGACAAGATACTCACCAGGACCAGGAAGGGGACTC TGGGGGACTGGCTTCCCCTGTGAGCAGCAGAGCAGCACAATAAATGAGGCCACTGTGCCA GGCTCCAGGTGGCCTCCCTGCCCTGTC OMIM ID 612339