Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SOCS2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8835 Official gene symbol SOCS2 Full name suppressor of cytokine signaling 2 Aliases ,CIS2,Cish2,SOCS-2,SSI-2,SSI2,STATI2, Gene summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq] Location Chromosome: 12   Locus: 12q Gene position 93963598 - 93969978  Map Viewer Gene orientation plus Gene size 6381 bp Gene sequence >SOCS2:56106904..56113284:Length=6381 AGCCGCGGCCTCAACTAAAAGTGGCCATTGACCTTTCAAGCTTTCGAGCAGTGATGCAAT AGAATAGTATTTCAAAGAAAAATGCTTATCGAAATTTTGGATCCGGTTTTCCCGTGATTG TTAAGGGTTTCTTTTAAAAAGTAGGTCACATTTCAAGTAGGTCATATTTCGGGGGCGGGT GCGCAGACAAGGAGATGAGTTTCCACTAAGGCCAGGGGGCCTCCAACGGGGTTGGAGGTG AGAATCCCAGGTAGGGTAGAGGTGCCGAGATCCTTCCGAATCCCAGCCCTGGGGCGTCAG CCCTGCAGGGAATGGCAGAGACACTCTCCGGACTGAGGGAACCGAGGCCAGTCACCAAGC CCCTTCCGGGCGCGCAGGTAAGGGCGCCCCCTTAGCAGCCGGCGCAGGTGACCCGGGCGG GCCGCCGGGTCTACCGGAGACGTTGGAGCAGAGGGGAGGAGGAAGGGAGGAGCCGGGTGG GTGCGGGTGACAAGGAGCCGGAGCGCCAGGGGGAGGGGACTAAGGACGGCCGGCGCCGCT TAAGGAGGCGCTGCTCTCCCGCTCGCTGCCTTCCAGGACCTGATCAAGGGGACCGCCTCC GGTCCCCGGCCGTGGGCACCGGGACGAGCACGGCGTCCCCACGCCATCGATGTGTCTTAG AGCCGGAGAGTCTGGTTTCCGAGGACCCACAGTCGCTCCTGCACGCCCACCCCCCGCAAA AGTGCGGCCAGGAGGGTCGCATCGAGGGGGCGCCGCCGGGATGTTTAGAGGAACCCACCC CCGTGGCAGGCCAAGGGCCAAGGATCGCTATCCTTCCCTGAACCCGGGCGCTCAGCTGGC CCGGGTAGGGGGCAGGCTCCGGCCGCCGAAACGGGGTTGGCTGTAGCCGGTGGCCGGGGA GATCTCTAGCTTGCGCCCGAGCACCCCGGGGTGTGGGGCCAGAGGCAGGCCGACCCCGGC GTGCACACCGCCCGCCCTGCACCCGAGCGCTCTCACCCGGTCTTCCCTGAAGCCTGTGTA TTGCGACCGAGCCTCTTTAAAGCAGTAGCGGGGCCCGCGGTCACGTGAGGCCGATTCCTG GAAAGTTCCTGGAAAGCCGCCTCCGCAGCAGCCGGGCGGGGCGCGAGCGGAGCGCTGACT GGGGAGGGAGGCGGGGAGCAAGGGAGGCGCGTCGGTCTGGGAAGTCGCGCGCACTCGCTG CTCCTGGGACCGACGTTTAACTCTTGCCAAGTCTCGTCGCAGCCGCCGCGGCTGGCGGGC CTTGGGCTTCCCCTGAAGCATGAGCCCTCTCGCCCGCAGCCACCCTCACCGCGTGGCCCG CGGACAGTGCGCGCCGGGGTCCCGGGTGCACAGCCTCAGGATACCCCGTGCCCGCAGCTC GGGCGCCCGCGGCAGGTACCGGTAGTGGGGGAAGCCCGAAGGCTCCGCCCCGAGGAGAGT TACCGGGGAGGGCGGCGAGGCGCGGCCGCGTGCGCCGGGGAGCGGCGGACGGCCTGGGCT TCCGCAGCTCGGAGCGCCGGGGAAGAGAGAGTCCGAACCGCGGCTCTGCCCCGCGGCCTA GCGTTGCTGCCTGCTTTCTCCAGCCCCTTCTCGGCGTCTGGAAGTGTCTGGAGTTTCTTT TTTTTATTTCCCCTAAACTGCCATTCAAATTAATAATCCTCCTAATAACCTGATCTCCCG CTCCTCCCCACCGGCCTGCCTCCCGCCCTCGCTCCTTCCTCCCTCCCTCCCTCTCTCCTT CCCACCTCCAGGGTCGCAGCCGGAGGGAAACCCGGCAGCAGTCCGAGAGTGGAGGTGTCC CAGCCCGTAGGGGGCGTCGCCGCGCGGTGGGGGATGGGGTCGAGGCAATGATCCTCGAGG CTTTTGTGTGCCCTCTGCGCACGGAACTCCGACCGCCGCCTCCGAGCGCGGGGCTGGTTG CATCCCCGGGCATCTCGTTCCCAAATTAAACGTTAACGGGGGAAACAAGGGCAGACGCCC CTCCTCTCCCGGGCCCCTCCCACCTCCCCTTTTCCCCCCACCCCCCCGCCCCATGTCCGC TGAGGAGGCTGCCTGGTGCGGAGGCGGCGGCGGCGGCCGCGGCCGAGGTCGAGGTAAGAG CGCGGCGTTGGTGGTTTGCATTTTCCGCAGCGCTCGCGACCGCCCGCTCGGCCCCGGCCT CGCCTCGGAGCCCCGCGAGGGCTGCGCGCTCGGGCCGATTCCTCGACAGCGCCCGCGGCG GCGAGAACCACCGCAGCCATCCTGGTCCGGGAGCGACCGCCGCGGCACCCCCAACCCCGC CAGAGCGGGCACCAGGAAGCGGGGGGAGGGGAGCGAGGAGCCTCCCGGGCGGAGATGCGG CAGCTCCCGCACCTCCGCACCCCGGGTTGGTGCCTCGGGGCCCCGCAGCGCTTTAGGGCG GAGAACCAAGTTTGTGTGGGTGCTTCTTCCTGGGGGCCCTCGGGCTGCGCCAGGTGTGAG ACCGGAATGCCAATTTGGGGAATCTCTCCTGTTCTTTCCTTTTTAATTTTTTCTACTTGT CCTTGACAAGGGCCTATTCCCACTGGATCTGCAGGTGACTATTTGCTCTTCCTAGGTCGC CAGTCTTTGATTTCAGCTAGTGACCCTGGGCGGGAAGACACCCTGTTCACCCTCCTCCTG ACCTCCGCCCCCCACCTCTTCAGCCAACTTTATCTTGGATCTCTGCTCTCTTTATCTTTT CTCTAGAGCTGGGCCAGGGCGCTAACTGGAAGCTTGGGGTTAAATGGTGCAGGAACGTAG AGGCGGAGGAGTCCCTGGGATTTTCCACGTCTATTTCCCCACCCCCACCCCAGCCGCAGG GGTCCAGTTTGGACTGACCCAACCTCCCGCTTTCTCTTTGTAGGCGATCAGTGGGTGACC GCGGCTGCGAGGGACTTTGTCATCCGTCCTCCAGGATCTGGGGAGAAAGAGCCCCATCCC TTCTCTCTCTGCCACCATTTCGGACACCCCGCAGGGACTCGTTTTGGGATTCGCACTGAC TTCAAGGAAGGACGCGAACCCTTCTCTGACCCCAGCTCGGGCGGCCACCTGTCTTTGCCG CGGTGACCCTTCTCTCATGACCCTGCGGTGCCTTGAGCCCTCCGGGAATGGCGGGGAAGG GACGCGGAGCCAGTGGGGGACCGCGGGGTCGGCGGAGGAGCCATCCCCGCAGGCGGCGCG TCTGGCGAAGGCCCTGCGGGAGCTCGGTCAGACAGGTAGGGAGCCGATCGGCCGCGACGC GTGCGGGAGGGAGCGCCTCCCCAAGGAAGCAGCTAGGAAGCGGGGTCGAGGTGGGAAGCA AAGAATAAGATGGAAATACGTCCCTTGCTTCCAAGGGACCGCGGAGAGCACGCTCGCAGG GTCCTGGGTCCTTGGGAATGCGTAAGGAAAGTGGTTCTCCAGGGACTCAGGCCTGGCGGA GCGCAGAGCGCGGGAAGAGCTTCTTGGAAATAGCTTCTTAGCACGCTGGAAGATTTACTG TTTTCCGCAGCTGCTCAGGGTTAGGCTCCCGGGCTCGAACCCCGGCCGGGGAAAGCGTCG GGCGCCTCCCTTTGCACGGGGTGCAATCAGCAAGTCGGTGCCGCGGGCCCCGCAGGCCCA GCAGCATCTGGCTCCCGGGCGGAGCTGCGGCTGCAGCCCAGGATCTTGGCGGCCAAGTTC AGGGACTGACACTGCCGCGAGGGCGGCTGCCCGGGCGTCGAGAGTAGGCTGCGAAGCCCC CGCCGAGCGCGGCTTCCATGGTCGGCGCGCCCAGGGTACTGCCGCTTTCAAGTACAGTCA GGCAATTCGCGCGGCACGCTGTCTCTAGGCATCTGAAAAAAGAAAAAAGAAAAAAAGTAA AGTATCTGGCAAATCATTCTGGCTTTCCAAATCCGTATCCTAAAAGCTTACAGTTGTGGC ACAGTTGAAATTTTGGTAGCAACAGGGGGAGGGAGAGGGAAAAGTTCTCTCGCTTGCGAT TCCGGTCTTTCCGTGTGGGCCACGGGCTTTCCCTCCCGGGGAGGCACCGGCAGATTGCAA GTATCCCGGTAATTGTGGGGGTGGGGGGAGCACAAATGTTCAGACTTCTTAAATACGGAC GGTCTCTGAGCCTTCTTAGAAAGCAGAGTGGGCCGGGGAGATGGTGCAGGCAGATGAAAT CAAGAATGCAGGGGAGATGGATGGTTGTGATTGGGTTTGGATTAGGGCAAAGTTCAAAAG AGTTTAGGGAAGATTGTAAACTTGAAGTAGTAATTATCACTTGGGAATTCCCATTTCTTA GTGACTGGTAAGGTAGTCATAAAGCAGCGAACAGAAGCTATTGTACTAGAGCTGTGCTTT TACAACAAGTACATAGCAGTGCTTTCTACATAGAAGGCTGTTCATAGCAGGCTTTGCAGA TTCTTTTTTTTTTTTTTTTTTTTTTTTTGGTGGGGGGCACACCAACCATCCAAAAAAGTT GCTTCTGTTTTTACTGTAGTTCAATTACAGGAGTTGGGTTTTCCACTTTTTAAAGGGCAT GGCTTTTATTTCTAACTTCTGATTTTTTTCTAATTTACCTAAATCTTTATTTTACTTAAA TAATGTTAAAAGTGTCATGCTTCATCAGCCAGTGTGTCATGCTGCAGATGTTCTTTTGGT TCATTAGAAGAAAATCTTAAGAAGAGCTTCAGAAAGTTGATTTTTTAAAAAAGAAAGAAA ACTGGCTCGCCGTTTGTGTTCATAAAATGGACCCAAATTTTTATTAAATTCCTACTGAAA GTATTTGTGGTGGCCCGGTAAACTTTCGCTCACACACCACCTTTTTTTTTTTTCTTTTTT AGAGCTAAAAAAATTATTGCCAATTACTTGCTCTGTTCTAAGAATTCTTATAATAACTGT TTTACCCTCTTTTCTTTTTCTTTTTGAACAAAAACCCCAGGATGGTACTGGGGAAGTATG ACTGTTAATGAAGCCAAAGAGAAATTAAAAGAGGCACCAGAAGGAACTTTCTTGATTAGA GATAGCTCGCATTCAGACTACCTACTAACAATATCTGTTAAAACATCAGCTGGACCAACT AATCTTCGAATCGAATACCAAGACGGAAAATTCAGATTGGACTCTATCATATGTGTCAAA TCCAAGCTTAAACAATTTGACAGTGTGGTTCATCTGATCGACTACTATGTTCAGATGTGC AAGGATAAGCGGACAGGTCCAGAAGCCCCCCGGAACGGCACTGTTCACCTTTATCTGACC AAACCGCTCTACACGTCAGCACCATCTCTGCAGCATCTCTGTAGGCTCACCATTAACAAA TGTACCGGTGCCATCTGGGGACTGCCTTTACCAACAAGACTAAAAGATTACTTGGAAGAA TATAAATTCCAGGTATAAATGTTTCTCTTTTTTTAAACATGTCTCACATAGAGTATCTCC GAATGCAGCTATGTAAAAGAGAACCAAAACTTGAGTGCTCTGGATAACTATATGGAATGC TTTCTAAGAACAGCTGAAGCTAATCTAATTTAAATTTAACAGCTTGAAGAGGTAGCTAGG TGTTTAAAGTTCCTCCAGATACTTTTACCTGAGTGATGCTTCCCTTCCTAAGGCTGACCA AGACCTGTTGATCCTTTTAGATTAAAAATAAAATGTCGCATGTAAAGGCTGAAGTCGCGT TTTATCAGAATGCCTTGCCTTCTTAGGTTCTTTTCCATTATGTCAAAGGTCCAGGCTCCA GTAGGAGAGAAAGAACTCCTCATAGGAATACTGAAGAAGTGGGAAGGAACCAAGCTGACA CAGGCCTCACTGCAATTTGATATGCCTGCTGATCAGAGTCTCTTGGGCATTTTATATTTT GCATTCTGATGTACCTAGGAGTTTTGTTAAACAGATGATGTATGTGAGTATTTATCCCAT TTTATGCAATTAACCAAATCAACCAAAAAAAGTGACCATGAAGTCCTGTATTTGTCTTTT TACTACATGTAGGAACTCTCATGTGAATGAGTACTGTAGTAATCCATTCTATGGGAGCCT TATTTCAGAAATATTTCAAACTGGTGCAAATGGAAAAGACTTTCTCTTTTCCTTTAAAGC TAAAGACAAGAATATCATGCTATACAGGTGCAACTCAATCCCCGTTAATAAAAACCAATG TAGGTATAGGCATTCTACCCTTTGAAATAGCTGTGTCCCAACCTGTTGCCATTGATTTTT TGGAAATGGCTTTAGAAATATCCAAGTTGTCCTTGAATTGTCTAACCATGGACATAAACA GTTGTCTCCCTTCTACTGTGTAGAATACTTTGACTTAATTTTCTTCCAGATACAGGGGGA TACCTGCCTGTTTTTCAAAGTGTTTATTTACTGCTGTTACTATTTGATTAGAATGTATTA AATAAAAAAAACCTGATTTCT OMIM ID 605117