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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NUMB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8650
Official gene symbolNUMB
Full namenumb homolog (Drosophila)
Aliases,S171,
Gene summaryThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q24.3
Gene position73925286 - 73741918  Map Viewer
Gene orientationminus
Gene size183369 bp
Gene sequence
OMIM ID603728