| Entrez gene ID | | 863 |
| Official gene symbol | | CBFA2T3 |
| Full name | | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| Aliases | | ,ETO2,MTG16,MTGR2,ZMYND4, |
| Gene summary | | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq] |
| Location | | Chromosome: 16 Locus: 16q24 |
| Gene position | | 89043401 - 88941267 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 102135 bp |
| Gene sequence |
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| OMIM ID | | 603870 |