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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC9A7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84679
Official gene symbolSLC9A7
Full namesolute carrier family 9 (sodium/hydrogen exchanger), member 7
Aliases,NHE7,SLC9A6,
Gene summaryOrganelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23. [provided by RefSeq]
LocationChromosome: X   Locus: Xp11.3-p11.23|Xp11.3
Gene position46618472 - 46466373  Map Viewer
Gene orientationminus
Gene size152100 bp
Gene sequence
OMIM ID300368