| Entrez gene ID | | 84679 |
| Official gene symbol | | SLC9A7 |
| Full name | | solute carrier family 9 (sodium/hydrogen exchanger), member 7 |
| Aliases | | ,NHE7,SLC9A6, |
| Gene summary | | Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23. [provided by RefSeq] |
| Location | | Chromosome: X Locus: Xp11.3-p11.23|Xp11.3 |
| Gene position | | 46618472 - 46466373 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 152100 bp |
| Gene sequence |
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| OMIM ID | | 300368 |
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