| Entrez gene ID | | 84311 |
| Official gene symbol | | MRPL45 |
| Full name | | mitochondrial ribosomal protein L45 |
| Aliases | | ,MGC11321, |
| Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq] |
| Location | | Chromosome: 17 Locus: 17q21.2 |
| Gene position | | 36452998 - 36479101 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 26104 bp |
| Gene sequence |
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| OMIM ID | | 611850 |
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