| Entrez gene ID | | 81792 |
| Official gene symbol | | ADAMTS12 |
| Full name | | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| Aliases | | ,PRO4389, |
| Gene summary | | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5q35 |
| Gene position | | 33892124 - 33527286 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 364839 bp |
| Gene sequence |
| |
| OMIM ID | | 606184 |
|