| Entrez gene ID | | 79589 |
| Official gene symbol | | RNF128 |
| Full name | | ring finger protein 128 |
| Aliases | | ,FLJ23516,GRAIL, |
| Gene summary | | The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] |
| Location | | Chromosome: X Locus: Xq22.3 |
| Gene position | | 105937068 - 106040246 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 103179 bp |
| Gene sequence |
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| OMIM ID | | 300439 |
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