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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BIRC7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 79444 Official gene symbol BIRC7 Full name baculoviral IAP repeat-containing 7 Aliases ,KIAP,LIVIN,ML-IAP,MLIAP,RNF50, Gene summary The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq] Location Chromosome: 20   Locus: 20q13.3 Gene position 61867276 - 61871854  Map Viewer Gene orientation plus Gene size 4579 bp Gene sequence >BIRC7:603907..608485:Length=4579 CCCTGGGATACTCCCCTCCCAGGGTGTCTGGTGGCAGGCCTGTGCCTATCCCTGCTGTCC CCAGGGTGGGCCCCGGGGGTCAGGAGCTCCAGAAGGGCCAGCTGGGCATATTCTGAGATT GGCCATCAGCCCCCATTTCTGCTGCAAACCTGGTCAGAGCCAGTGTTCCCTCCATGGGAC CTAAAGACAGTGCCAAGTGCCTGCACCGTGGACCACAGCCGAGCCACTGGGCAGCCGGTG ATGGTCCCACGCAGGAGCGCTGTGGACCCCGCTCTCTGGGCAGCCCTGTCCTAGGCCTGG ACACCTGCAGAGCCTGGGACCACGTGGATGGGCAGATCCTGGGCCAGCTGCGGCCCCTGA CAGAGGAGGAAGAGGAGGAGGGCGCCGGGGCCACCTTGTCCAGGGGGCCTGCCTTCCCCG GCATGGGCTCTGAGGAGTTGCGTCTGGCCTCCTTCTATGACTGGCCGCTGACTGCTGAGG TGCCACCCGAGCTGCTGGCTGCTGCCGGCTTCTTCCACACAGGTCAGTCCCGGGCGGGGG GGCCTTCCTGCCGTGGGCCTGGGCACGATTCTGGACCCTTCCAGCCCAGGGCTCTGCCTC CTCCGTAGCATCCATCCCCCAACAGGAAGGGTCTGGCCTGATGACGGAGCAGTGGTCCTG CAAGCCCCTCCAGTGCCCATGGGCTCGTGCCTGACACCCTCCCCCGGAGTCTCTGCTGGC TGAGTGTTTCAGACCGTGGGATGTGAGGAGGGGCTGCCTCTGGCCACAGTCTGAGGGTCT CAGCTGTGGAGGCCGCCAGCTTGGTGCACAAGTACCCCTTTGTGATAGAAGTGGGTGGGG CTGACATTGCCTGGGGCCCTCACCTTCCCCGCTGCTGTTCTGCACAGGGAGAGGAGATGT TTAAAGAACAGGATCAGGGTGACCAAGGCAGGCAGTGGTCAGCCAGAAGGTCCTGGATGC TCAGCCTGTGGGGAATTTCTCCAGGCCCCAACCTGCAGCTACTGTCTGGTCTTCCCCAAC TGAATCAAGTCCCCGGAGTACCTATCCTAGTCTTGGCCCGGGCCTGCTCCTCTGCCCTAC AGCTGCAGACCATGTGGTCAGACCTGAGTTCAGGTCCCAGCTCTGCCACTTCCTGGCTGA AGGACAGGGCAGCAGGGCCCACCGAGGGCTTTACAAATACTGGCACAGCCATGGTCATTG TCAGCAGTGGGCTCTGGCGGGGCACCATCCTGGTAAGGCTGGACCAACTTAAGACAGCTG GTCGGGGGGACAGTGGCTGGGACAGTCAGAAGCCGTGGCGTGAAGGGGCAGGCCCAGCTC ACCCACCTCCCTGGAAGTCCAAGGCTCAGGAGGCAAAGGCCAGGCAAGAGGCATGGCAGG TGCAGAGCCGGGGTCTTTGGGGCTGGTAGAGGTCCAGTGCCCGATGCAGCCCAAACCTGT GATGTCAGTGGCAGGTGACGTATCGCATGGATGCCGATGAGGGGACGGGGTCGCCAGGAG GTAGAGAGATGACGGGTCCCCCACCCCCAAAGGGAGGCATGAGTTCCTAAAAGCAAGCCT GGCCCCAGACTGGCCTTCTAGGGCAGCCTCCCTTCTTCTTCTCACTGGGAATCCATCTTG GGGAAGCAGAGACCTGGGGAGGGGCCCTTCTGGCTCCTGAAGCCCCAGGGCTATAGATGT ACCAAGCCCTGGGGGGCCCCCACTGCTCACTCTGGGAACAATGCAAATGCCAGCTCAGTC CTTTCCTGAACATTCTCGCCCATCCTGGCCGGCACCCCAGTCACCCTTGTCCCCTTTTCA CCTTTGATGCTAATGAGGTACAAGTGACATCCCCCACCAAGCCCCCTGCCCACCCCCTCC TCCTTCTTGCCACCTGGGAGCTCCCCTCCAGCTGAAGCTCTCATAGCCTTGGAAGGACAC ACCGGGGGCCCGGGGACTGGGTGGGACTTGGCTGGGGCCAGCATCTCTCCGCACCCCAGG CCATCAGGACAAGGTGAGGTGCTTCTTCTGCTATGGGGGCCTGCAGAGCTGGAAGCGCGG GGACGACCCCTGGACGGAGCATGCCAAGTGGTTCCCCAGGTACCGGCTGCCCCTGCGGGG CCCCGGGTCTGATCATGGGTAGGGGGTGGGCCCCCAACGGCTCTGTCGACCCAACACCAG GCCTGCTTTGCCTCCCTGGCCCCACAGGGCACTGGGGAGGCCCTTCTGTGGGAGGTGCTT CTGGCCGGCAGGTACCCACTTTTCCTGTGAGGGCCCCTTTTCGGAAGGGCTGCTGGGGGC AGAAATGCCTCTCCCATGGGACTACCCTGAAGCCCCATGGAGGCGTCTCCACAGCAGCCC TCCTCGCCCATGCCCACGGGCACTGCAGGGTGGCGGGAGGAGGGGGCCCAACCCTGACCC CCGGGGATCCAAGGGCTTGAAGCAGACAGTGGGGGCCCTGAACCCCAACCTACATCTCTG GGGCATCTGCAGCTGTCAGTTCCTGCTCCGGTCAAAAGGAAGAGACTTTGTCCACAGTGT GCAGGAGACTCACTCCCAGCTGCTGGGCTCCTGGGTGAGCGCCACCTCTCCTCGGGGCTC CGGGTGGCAGTGGGGTCCTGCCCCTCCTATTTCCCCAAGGCCTGATGGTCTCTGGCTCCT TCCAGGACCCGTGGGAAGAACCGGAAGACGCAGCCCCTGTGGCCCCCTCCGGTGAGAGCT GACACCACCCCTGCTGACTCCTTGTGCGCCTGCAGCCTGTGCTTGGCCAAGGCCACTGGG TGTCCCCACCCTCCCAGACAGCAGGGAGAGTGACGGGCACGTGACAGGGTGTGACGCTGC TGCCTGGGTTGGCTTCAGGGGGCTGTGCCATGTGAGGGTGGGGGCGGGGCGGCAGGGGCC TCCCCCAGTGCCAGGCCCCATTCTGCTTCTCTCCCAGCTTACCCCTTGGGCACAGCCCAT TGCCTGTCGCCATACCACCCCCAACAGTGCCCAGCACACAGCATCTGCAGCTACTGCCAG ATGGGCAGGATGTGCAGAGGGCATTGGACAAGGGACAGGCTCTCTGGTGGCGCCTCCAGG AAGCCTCTGGATCCTGTTATGCTGTGGGAGGGGTGGGAAGAAGTGTCGGGAGCGGGGATA CTCTGCAGCCCCTCCACTCCCGGCCAGAACTGGACCCCACAGGCTGCAGACCTGTATCTG GGCCGGCCCAGCTTTCTCCTTGGGAGTTAGGCCTCAAGTCTATCCTAACTGTCCACAGTC CCTGCCTCTGGGTACCCTGAGCTGCCCACACCCAGGAGAGAGGTCCAGTCTGAAAGTGCC CAGGAGCCAGGTGCAGGCCCGGGACCCCCTGGGTGAGGGCTGGGGCAGGGGAGGGCTGAG GGACCCCGACCTTCCATGGCCCATAGAGGGTGGGGGCCAGGGTGTGGGGACATTTCGCAG GCCTGTCCTCCTAGGAGGGGTCAGTCCAGCCGAGGCCCAGAGGGCGTGGTGGGTTCTTGA GCCCCCAGGAGCCAGGGATGTGGAGGCGCAGCTGCGGCGGCTGCAGGAGGAGAGGACGTG CAAGGTGTGCCTGGACCGCGCCGTGTCCATCGTCTTTGTGCCGTGCGGCCACCTGGTCTG TGCTGAGTGTGCCCCCGGCCTGCAGCTGTGCCCCATCTGCAGAGCCCCCGTCCGCAGCCG CGTGCGCACCTTCCTGTCCTAGGCCAGGTGAGCGCCCCAGCACCACGCGCAGCCAGCCCT CCTGCGGAGGGGGCCCTGAGCCGGCTGTGCCCGGCCCTCCTGAACCCATGCAGGCCCTTC CCGGGTGGCAGCGTCAGCTTGTTTTTACCCGGCTCCCAGGTCCCGCTGATAGCGCCCATC AATCTTACTACCTCCCTTGACGCTTAGGTTGGGGCCTGGTCCTTCGGGCACCGTGCCCTG GCGGCCACCATAGCTCTGCCTGCCTGCATTAACTGACGCCTGCTGGCTCCTCTCAGCCTT GATTTTCCTCAGTGGTCAAGGAAAGCCGGCTTTGGAGGCGTTTGGGGAAACAGGGTGGGC CAGGTTGGGCTTACACAAGCGAGACACTGGCCTGGCTTCAACCCGGGGCCAAGGCATGGT GGGAACACCTGCACGGGAAGGGGGTGTGTGAACCTGTTCTTAGAGAAGTGGGTGGGATAC CCCATACTGGCCGAGGGACAGGTGCTGTGACCGCCTCGGGGCTCCCCAGAGCCTCTGTAG TTACCCCCGGGATGTGTCTGAAGATCTGGCAGGGGACAAAGTGGTCGGGCAGGGAACTCT GGGATCTGAGGCCCCTGGCTAGGTGGGCCCCGTCGGTTGCCATTGACTCACCCACCCCTC CTCTCCCTCTAGGTGCCATGGCCGGCCAGGTGGGCTGCAGAGTGGGCTCCCTGCCCCTCT CTGCCTGTTCTGGACTGTGTTCTGGGCCTGCTGAGGATGGCAGAGCTGGTGTCCATCCAG CACTGACCAGCCCTGATTCCCCGACCACCGCCCAGGGTGGAGAAGGAGGCCCTTGCTTGG CGTGGGGGATGGCTTAACTGTACCTGTTTGGATGCTTCTGAATAGAAATAAAGTGGGTTT TCCCTGGAGGTACCCAGCA OMIM ID 605737