| Entrez gene ID | | 7515 |
| Official gene symbol | | XRCC1 |
| Full name | | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| Aliases | | ,RCC, |
| Gene summary | | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq] |
| Location | | Chromosome: 19 Locus: 19q13.2 |
| Gene position | | 44079730 - 44047464 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 32267 bp |
| Gene sequence |
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| OMIM ID | | 194360 |