| Entrez gene ID | | 7405 |
| Official gene symbol | | UVRAG |
| Full name | | UV radiation resistance associated gene |
| Aliases | | ,DHTX,p63, |
| Gene summary | | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq] |
| Location | | Chromosome: 11 Locus: 11q13.5 |
| Gene position | | 75526212 - 75855282 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 329071 bp |
| Gene sequence |
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| OMIM ID | | 602493 |
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