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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBA7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7318 Official gene symbol UBA7 Full name ubiquitin-like modifier activating enzyme 7 Aliases ,D8,MGC12713,UBA1B,UBE1L,UBE2, Gene summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq] Location Chromosome: 3   Locus: 3p21 Gene position 49851391 - 49842638  Map Viewer Gene orientation minus Gene size 8754 bp Gene sequence >UBA7:complement(49782638..49791391):Length=8754 CTTTTCTTTTCTCCAGGAAGAGAGCTGTGACCAGCAGCGTCCCTTATTCGCTTGGCCTTG GTTCCTGTTTGCACTGGCTACAGCAGGGCACTGGCCCCTACTGTCACCGCCACCTACACA AAGACCCTATCTCTGAGCGCTGCAGCCTACTGTTCAGCCCCAGGTTTGAGGATGGATGCC CTGGACGCTTCGAAGCTACTGGATGAGGAGCTGTATTCAAGACAGCTGTGAGGCCCGAGG TGGGGGGTGGAGAGTGGGATGGTCTTCAGACCTTGATCTACAACTGCTTGCCTTCTGCTT CCCATCCACAGGTATGTGCTGGGCTCACCTGCCATGCAGAGGATTCAGGGAGCCAGGGTC CTGGTGTCAGGCCTGCAGGGCCTGGGGGCCGAGGTGGCCAAGAACTTGGTTCTGATGGGT GTGGGCAGCCTCACTCTGCATGATCCCCACCCCACCTGCTGGTCCGACCTGGCTGCCCAG GTAAGTGTCCTGGGGGGCTATGGGCTGCCAGACCAAGGTGGGGGCACGGCCCAAGAGGAG TGTCTTTGCTCAGGCTGCACTGGCTCTCTCCCTAGTTTCTCCTCTCAGAGCAGGACTTGG AAAGGAGCAGAGCCGAGGCCTCTCAAGAGCTCTTGGCTCAGCTCAACAGAGCTGTCCAGG TCGTCGTGCACACGGGTGACATCACTGAGGACCTGCTGTTGGACTTCCAGGTCAGCTCAG GCCTGCAGCCCTCAAGAGCAGGAAGGGCTGGGCAATGGTTTTGGCCCTGCTGATCACTGT GTCCACCCAGGTGGTGGTGCTGACTGCTGCAAAGCTGGAGGAGCAGCTGAAGGTGGGCAC CTTGTGTCATAAGCATGGAGTTTGCTTTCTGGCGGCTGACACCCGGGGCCTCGTGGGGTG AGTAAGACTGCCTGCCCAGCCTACCATATTACAGCCAGCAACTGGCCTCATGCTGTCCTC AGCTCCAGGCTTGCTCCAGTGCCCCTCCAACCAGCCTCAGGTCTATCCCAGCATGCCTTT CTGATTCTGGTCCCCAGTCCTGCCCTCTGGTTCCTCCAACCTAGCCTCCAGACCTGCTCC AGTAACCCTCTCAAATTCTAGTTCCCAAGCCTCTCCTTGCATTCCTTTCCCAATTCTGGC CCTCTGGCCCTGCCCTAGTATCCCCTATCCTTAAGTACAATCTGTAAGCCACCTCAGTGA CCCCTACCACCCCATCTCAGGCAGTTGTTCTGTGACTTTGGTGAGGACTTCACTGTGCAG GACCCCACAGAGGCAGAACCCCTGACAGCTGCCATCCAGCACATCTCCCAGGTGGGTGCT GAGCTGTAGGCATTCACCTGCTGACCAAGGAGAGGCTGCCAGGGCCTGTGGAAGGCAGGT CCAGGCAACCCTGAGCCAAGCCTCCTCCTACCCAGGGCTCCCCTGGCATTCTCACTCTGA GGAAAGGGGCCAATACCCACTACTTCCGTGATGGAGACTTGGTGACTTTCTCGGGAATTG AGGGAATGGTTGAGCTCAACGACTGTGATCCCCGGTCTATCCACGTGCGGGGTAAGCCAA TCCCATTCCAATTCCAGGTGCAGGGCCCAAGCCTCCACTGGAAGTGAGCACAGCCTGGCC CTTGGGATGGGTTTTTCTCCCTCCACCTTCTACAAGGTGCAGCAAGGTCTGGGACACAGA TGCAAGATAGGATGGGGTGTGGGAACTACTCAGGCTCAAGGATCATTACTGACTAGACTG GAACTCCCTCAGAGGATGGGTCCCTGGAGATTGGAGACACAACAACTTTCTCTCGGTACT TGCGTGGTGGGGCTATCACTGAAGTCAAGAGACCCAAGACTGTGAGACATGTGAGTGCAA GTGCATCTGAGGTAGGGGAGCTTGGTCGCCTTGAGGGGCCCATAGCATTCTGGACTAGAC CCTGAGCCAGGTGCCCTTGCAGAAGTCCCTGGACACAGCCCTGCTCCAGCCCCATGTGGT GGCCCAGAGCTCCCAGGAAGTTCACCATGCCCACTGCCTGCATCAGGCCTTCTGTGCACT GCACAAGTTCCAGCACCTCCATGGCCGGCCACCCCAGCCCTGGGATCCTGTGAGTAGTCC TGTTGCTCCCACCCCCAGCCTCTGTCATTTATTGGGGTCCCACCTGCCAGAGGCAACAAT GACCATTCACAAATCCAAGTCTGATCTCCCAACACTGCAGCCTTTAGAGTAGAGACTGGT TCCATGGAAGTGCCAGGCACACATCCTGGGGACTCCTGCTACACCCCGACCCCTCAGATC TGTGCTGGAAGCTGCACTCAGATTAGTGAAGCCTCCTGGACTGCTGTCTGGTACTGGGCA TCCTCTGGTGGTGCTGTGCAGGCTGGCAGCAGGGCCAGGCCTTCCCACCCAGGCTTCTGC TTCCTCTTCTGTGGAACAGGGTGGATGGAGGGTGGCTGGAAGGATTTGAGTCAGGAGTAG AGCTCAGGCTGGGGCTACTATGCCCACAGAGTCCTACCAACAGGTTGATGCAGAGACTGT GGTGGGCCTGGCCCGGGACCTGGAACCACTGAAGCGGACAGAGGAAGAGCCACTGGAAGA GCCACTGGATGAGGCCCTAGTGCGGACAGTCGCCCTAAGCAGTGCAGGTGTCTTGAGCCC TATGGTGGCCATGCTGGGTGCAGTAGCTGCCCAGGAAGTGCTGAAGGTGGGCAGAGGCAT AGGTGTGGGGGGTACTGGGAAGATGTGGAGATCAGTGTGTGTGTCAGAGGGCACCCAGCG CTAGAGAGCAGCCCTGGAGCCTTCACCAACCTGGGTGAAGCCTCCAGCCAGGATCTGAGG GGGGTCAGGAGGTGGCAGGAGTGCCCAGCCTGAAGTGCTGCCCCTAGGCAATCTCCAGGA AGTTCATGCCTCTGGACCAGTGGCTTTACTTTGATGCCCTCGATTGTCTTCCGGAAGATG GGGAGCTCCTTCCCAGTCCTGAGGACTGTGCCCTGGTGAGAGCCTGGGATAGGGGTGCAA GCCTTGTCCAAAATCAGGACTAGGGGAGAAGCATGAGGAATGCCCTCCAGGTCCTGATTC AGAAAACTCAGTATAAGAAGGAGATGCAGGCCAGTAGCCATCACTGACCCCGTCTCTGTC CCCTAGAGAGGCAGCCGCTATGATGGGCAAATTGCAGTGTTTGGGGCTGGTTTTCAGGAG AAACTGAGACGCCAGCACTACCTCCTGGTGAGCTGTGGGGTGAGACTGGGGGTGCCTTTG GGAGAGCCAGCCCAGCCCCTCTGGCTAAGGCTGTTCCTGCCAACAGGTGGGCGCTGGTGC CATTGGTTGTGAGCTGCTCAAAGTCTTTGCCCTAGTGGGACTGGGGGCCGGGAACAGCGG GGGCTTGACTGTTGTTGACATGGACCACATAGAGCGCTCCAATCTCAGCCGTCAGTTCCT CTTCAGGTCCCAGGACGTTGGTGTGAGTGCTGACCCCTCTCCACACTCCTGCATCCCAGA CCGTCCTCCCATACAGCTTCCCACCCAACATCTTCCTGCCTTCTTCCCAGAGACCCAAGG CAGAGGTGGCTGCAGCAGCTGCCCGGGGCCTGAACCCAGACTTACAGGTGATCCCGCTCA CCTACCCACTGGATCCCACCACAGAGCACATCTATGGGGATAACTTTTTCTCCCGTGTGG ATGGTGTGGCTGCTGCCCTGGACAGTTTCCAGGCCCGTGAGTGCTTGACTTCGGAGGTCA GTCCCTTGCCCACAGCTGTGCCAGTCCCACTTCTGACCCACTGCTCCCTTGCCAGGGCGC TATGTGGCTGCTCGTTGCACCCACTATCTGAAGCCACTGCTGGAGGCAGGCACATCGGGC ACCTGGGGCAGTGCTACAGTATTCATGCCACATGTGACTGAGGCCTACAGAGCCCCTGCC TCAGCTGCAGCTTCTGAGGATGCCCCCTACCCTGTCTGTACCGTGCGGTACTTCCCTAGC ACAGCCGAGCACACCCTGCAGGTAGGAAGCACCCTGGAGACTCCCACCCCACCCAGCTCA GCCCTCAGCTGCAGACCTGTTCTCCACCTGATACCTCATTCTTCCTCCCTCCTCCACAGT GGGCCCGGCATGAGTTTGAAGAACTCTTCCGACTGTCTGCAGAGACCATCAACCACCACC AACAGTAAGGCCACCAACAGAGGCAGATGGGAGTCCAGGGCTCCAAGCATGAGTCTGCAG GACTCAGTCTCACACTTCCTCCTCTCTCTGCAGGGCACACACTTCCCTGGCAGACATGGA TGAGCCACAGACACTCACCTTACTGAAGCCAGTGCTTGGGGTCCTGAGAGTGCGTCCACA GAACTGGCAAGACTGTGTGGCGTGGGCTCTTGGCCACTGGAAACTCTGCTTTCATTATGG CATCAAACAGCTGCTGAGGCACTTCCCACCTAATAAAGTGTGTGGCTAGGGGTTGGGACG CTGGGGGCTCAGGGGGACCAGACTGAGCCCAGCAGCTTCTACTTACCTACCTAGGTGCTT GAGGATGGAACTCCCTTCTGGTCAGGTCCCAAACAGTGTCCCCAGCCCTTGGAGTTTGAC ACCAACCAAGTGAGTGGGATTCTGTAGGGAGCTCCAAGATAGAGATGTGGCCCCTCAGAG CAGAGGTAGGCATTTCTGCATTCTGCAGAGATGCACAGATGCCCAGAGAGAGCCATGCTT GTGCATATATGGGTGTCTACATGTGAGGCAAAGGCAGGCACTCAAACAGATCCACAAATG GACAGTGACCCCCACCCCATGCACCCATGCCTCTGTTCCTGCTCTTGGTCTGGCTGCAGG ACACACACCTCCTCTACGTACTGGCAGCTGCCAACCTGTATGCCCAGATGCATGGGCTGC CTGGCTCACAGGACTGGACTGCACTCAGGGAGCTGCTGAAGCTGCTGCCACAGCCTGACC CCCAACAGATGGCCCCCATCTTTGCTAGTAATCTAGAGCTGGCTTCGGCTTCTGCTGAGT TTGGTGAGGCTCCTGGCCCTGGCCCCTCATGCTGTCTTTCAAAGGCCTGAACCTGTCCTG TCCTCAGCCTGTGCTGCAGAAGGAAGATAGGGCCTAGGGGATCTACAGCCAATTTGCTAC CTCTCAGGCCTCCTAACCTCACTCCTCCATAGTTTCAGGCTTATCCTCTGGTCCCTCAGT AGGTCTTCTCCCTGCTGCCTACCCCACATCCCAGTTCTTGTGGCAGATTCTTGGCAAAAT AAATAAGTAAATAAATAAAGTCCATTGGTTCCTGGGGAGTGTCTAGCTATGGCCTGCAGG TGAGGACAGGGTCACAGAGGTCATGAGCACACATGGGTGAAGACTGGGGCTTCTAGAGGG GAGATTGTAGCATTAATTAAGGGGGCTTCTTGATTTGATCAGGGAATAGTAAGTGACAGG CTTGGCAAAGACCAAGAATAGGCACAGGGCTCCAAGAAGAGTGCAGGAGACAGGGGCTAA GGACTGCCTCAACATCCCCTCCCCTGACAGGCCCTGAGCAGCAGAAGGAACTGAACAAAG CCCTGGAAGTCTGGAGTGTGGGCCCTCCCCTGAAGCCTCTGATGTTTGAGAAGGTGGGTG CCCAAGTGGCAGTGAGGAGTGGGGCTGGGGAGTTTGTGGAGAAAGGTCAGGAGCTAATAA GGTAGTTTTGGAGCCCCTTGGCCTGAATTCTCCCAGCAAGACCCTGGAAGCAGCTCACAT TCCCTGAACCTCAGCCTGTCTGATCAAGAGGAGATGTGGGGCAACCCCCCGACAGAACTG TGTGGAGACTTGTGCAGTGACACGCAGTGGGCCACGGTGAGGGGCACAGCTGCAGTGTTA ACACTACTTTGACTTGGGCCTTACAGGATGATGACAGCAACTTCCATGTGGACTTTGTGG TAGCGGCAGCTAGCCTGAGATGTCAGAACTACGGGATTCCACCGGTCAACCGTGCCCAGG TAACCCCACCCCTTGAGGCTTGGGCCTGGAGGTGGAGGGCAAACCCTGGCCCTACGCCTT GGGCCCAGACCAAATCTCTTGTCCTTGGCAGAGCAAGCGAATTGTGGGCCAGATTATCCC AGCCATTGCCACCACTACAGCAGCTGTGGCAGGCCTGTTGGGCCTGGAGCTGTATAAGGT GGTGAGTGGGCCACGGCCTCGTAGTGCCTTTCGCCACAGCTACCTACATCTGGCTGAAAA CTACCTCATCCGCTATATGCCTTTTGCCCCAGCCATCCAGACGGTGAGCCCATGATACCC CACCCTTAGCCCTACTAGGCCTGGGTTTCCCCTGCACCTGCCCATACAGGCCCCAATCTA GCTGCCGGCTCTCACTGAAACTCAGACTGTGCAGAAGTCCTGAAGACTCCCTCCAGCCCT CTTCCTGCTATGAAGCCAGGCTGGGACCTGTCAGACACAGGAAGCAGCCGTCAGCCATCC CCACCCCCAATCCTCCAAAGCCCAGGATCTGGGGGAGCTGCAGCTTTAACTCATTAGTGG AGCCAGACATCCCCCACAGTCCCCTCCTTCCTTGGAGTACCCCTGAGGGGTAGGTAGTGG GGAGGGGACCAGGGCATCAGCCCCAGAAAGAGTCTAGCTTCCCCCTGCATGGTACGGGGG CCCTGGCCTACCTCCTACAAGCTGAGTTAAAAGGTAATAGGCTTGCCACTAGAGGTGTGG GGTCTGCAGCCCTGAGTGTATTTGTGTCACAGTTGTGAGTGCAACTGGGGTCTGGGCATC CCCGGAGTGTGGGTATGGAAGGAGCAAGTTTGCACATCTGTGCATCAGATGGGAGTGCAG GGCTCCCATCTTCCTGTGTCCTCAATGTGGGCATGCATGGAGATGCATGTGGGCACACAT GTGTGTGTTCCTGGGCTTGTGGGCATTTGTGTTCCTGTGACTGCAGCGCTGTGAATGCCT CCAGCCTTGTGCCCAGGCTCTGCAGTTGGCATTTCCTTGGGGCAAGGATGAGGGTAGAAG GAATGCCCTCATGAGGGGAGAGGGCAGAGGTCATGGGCCAGCACTGGGTTTCTGCTGAGC AGCCTGGGGTCCCTCTGGACTAGCACACAGAGCCCCTTTGTGAGGCACCCTGCCTCTAAC CAGCATACAGGCTGCCTTTGTCCACAGAGTGAAGCAGGTGAAGGAGAAGCCCCCATCTCA CCTCTAGCCTAGTCTCAGCTTGACCCCAGTGTGTTTTCTCAGGGGCTGATAAGCACCCCC TGTCCTGGTCTCTAGATACCTGCCAGCCATCCTTCTGTCCTTAGCTCTAGGTCCCAGAAC CCCAAGACTCTTGGAAGGAAGGAAGGGACAGGAGGAGGAAGCCTCTATGCATTGTATCCC TGCTGGGGTCTCTGGGACAGTGGGGCCCTGGTGGTCACTGTGCCCTTTGCCCCTGTGTCC CAATGAGTAGCCCAAGGCACTGGCAGTACATACAAGATTGGGGGACAGGATGTGCCCCCC AGCTCCCAGCCTTGTCTTTGAGGAACAAGCAGCTTTATCAGAGGCTGCAGGGGCCCTGCT CTGGGTTTCCTCAGGAAGCACCACCCCCTCATCCCCCACTCTCACAACTGGCCCATGTGA TGGATCGTCTGTTTCCCTGTGCGGGCCCCATAGCCCCATTTCCTGTGCTGGCCCCGGCCT GGACGGGGAGGGGGCTGAGACTCTGGGCCCAGATCCCACCTCCCCCCCACCCCCCACCCC CTGGCTCCTGTTTCCTGCTAGTCCAGCTCTTCCCCTAGGAAAGGCTGCTGGTAACTGGGA TGGGGGTTGGGGGGAGGTAAGAAGTCTCTGACTCCTCCTCTACCTCATCCCAGTTCCATC ACCTGAAGTGGACCTCTTGGGACCGTCTGAAGGTACCAGCTGGGCAGCCTGAGAGGACCC TGGAGTCGCTGCTGGCTCATCTTCAGGTGTGCCCTGTTGCTACCCCAACCCCCAGGCTCA GCCCAGCCCGGCCCAGCTGGTGTCTGACCTTTCTCCTCTAGGAGCAGCACGGGTTGAGGG TGAGGATCCTGCTGCACGGCTCAGCCCTGCTCTATGCGGCCGGATGGTCACCTGAAAAGC AGGCCCAGCACCTGCCCCTCAGGTGAGCCCACTTGGGGCTTTAGACAGGCCCCACCAGTC CCTGGAGGCTGGGGCTAGGGACCACACTGCCTTTTGTCTTCCCAGCCCCATTCTGGGCCC CTCACACCTTCCCAAGCATTCTTTCCCCAAATGGAGCCAGCAAACAGGCTGGAGGTGGGG TGAGGGCCGAGAGCCTGAGGAGGAGTCTTCAGGAGCTGCCTATTTGGCCAGCCCCATGGG CTCCCCACATGCTGCACAGCCCCCCTTTCACAGCCCACTCCCAAGGGACCCATAGCTTCC TGCCTCCTGCTTGCCTCATCAGCTGCTCCTAAAATAGTTTCAGATGTTTCCTGTCTTGAG CAGCTCCTGCTCCTGGCTTGGGCTCCTGACGGCCTGCCAGCACCCTCTCTAGTCCATGCC AGGCTGCCTTCTGCTTGCCATGGCTCACCTCTCCAATCTCCCCTAAACCCACCCCTACCA GGGTGACAGAACTGGTTCAGCAGCTGACAGGCCAGGCACCTGCTCCTGGGCAGCGGGTGT TGGTGCTAGAGCTGAGCTGTGAGGGTGACGACGAGGACACTGCCTTCCCACCTCTGCACT ATGAGCTGTGACAAGGCAGCCACCCTGTCACCTAGCTCAATGGAGCCCCGGATCCCAAGC CCTGCATTGTAAGCCCACAGTAGGCACTCAATAAATGCTTGTTAAAGGAAGGCA OMIM ID 191325