| Entrez gene ID | | 7225 |
| Official gene symbol | | TRPC6 |
| Full name | | transient receptor potential cation channel, subfamily C, member 6 |
| Aliases | | ,FLJ11098,FLJ14863,FSGS2,TRP6, |
| Gene summary | | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq] |
| Location | | Chromosome: 11 Locus: 11q21-q22 |
| Gene position | | 101454659 - 101322295 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 132365 bp |
| Gene sequence |
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| OMIM ID | | 603652 |