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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TIA1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7072
Official gene symbolTIA1
Full nameTIA1 cytotoxic granule-associated RNA binding protein
Aliases,-,
Gene summaryThe product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p13
Gene position70475779 - 70436576  Map Viewer
Gene orientationminus
Gene size39204 bp
Gene sequence
OMIM ID603518