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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TGFBI (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7045
Official gene symbolTGFBI
Full nametransforming growth factor, beta-induced, 68kDa
Aliases,BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1,
Gene summaryThis gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q31
Gene position135364584 - 135399507  Map Viewer
Gene orientationplus
Gene size34924 bp
Gene sequence
OMIM ID601692