| Entrez gene ID | | 7045 |
| Official gene symbol | | TGFBI |
| Full name | | transforming growth factor, beta-induced, 68kDa |
| Aliases | | ,BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1, |
| Gene summary | | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5q31 |
| Gene position | | 135364584 - 135399507 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 34924 bp |
| Gene sequence |
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| OMIM ID | | 601692 |
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