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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TARBP2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6895
Official gene symbolTARBP2
Full nameTAR (HIV-1) RNA binding protein 2
Aliases,LOQS,TRBP,TRBP1,TRBP2,
Gene summaryHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q12-q13
Gene position53894705 - 53900215  Map Viewer
Gene orientationplus
Gene size5511 bp
Gene sequence
OMIM ID605053