| Entrez gene ID | | 6868 |
| Official gene symbol | | ADAM17 |
| Full name | | ADAM metallopeptidase domain 17 |
| Aliases | | ,ADAM18,CD156B,CSVP,MGC71942,TACE, |
| Gene summary | | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq] |
| Location | | Chromosome: 2 Locus: 2p25 |
| Gene position | | 9695917 - 9629392 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 66526 bp |
| Gene sequence |
| |
| OMIM ID | | 603639 |
|