| Entrez gene ID | | 6781 |
| Official gene symbol | | STC1 |
| Full name | | stanniocalcin 1 |
| Aliases | | ,STC, |
| Gene summary | | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq] |
| Location | | Chromosome: 8 Locus: 8p21-p11.2 |
| Gene position | | 23712320 - 23699434 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 12887 bp |
| Gene sequence |
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| OMIM ID | | 601185 |
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