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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SSX2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6757
Official gene symbolSSX2
Full namesynovial sarcoma, X breakpoint 2
Aliases,CT5.2a,HD21,HOM-MEL-40,MGC119055,MGC15364,MGC3884,SSX,SSX2B,
Gene summaryThe product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
LocationChromosome: X   Locus: Xp11.22
Gene position52736249 - 52725946  Map Viewer
Gene orientationminus
Gene size10304 bp
Gene sequence
OMIM ID300192