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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SSRP1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6749 Official gene symbol SSRP1 Full name structure specific recognition protein 1 Aliases ,FACT,FACT80,T160, Gene summary The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq] Location Chromosome: 11   Locus: 11q12 Gene position 57103351 - 57093459  Map Viewer Gene orientation minus Gene size 9893 bp Gene sequence >SSRP1:complement(2399254..2409146):Length=9893 GTACGGCTTCCGGTGGCGGGACGCGGGGCCGCGCACGCGGGAAAAGCTTCCCCGGTGTCC CCCCATCCCCCTCCCCGCGCCCCCCCCGCGTCCCCCCAGCGCGCCCACCTCTCGCGCCGG GGCCCTCGCGAGGCCGCAGCCTGAGGAGGTAGGTGGTGGTCGTCCCCGGTCCCAGGAAGG CAGGGGCCCCGCTCCCCCACGGGACCCTCGACATGGACCATTCCGCGTTCGCAACCGCGG GGAGCGGGCGAATCCATTATGTGGGGCGGGGGTGAACCGTGGGTCTGGGGCCGCGGGGTG GTGGGAGCGGTGCGAGGGAAACCCTGCACTCTGAGCTGGATTGGGTCGCGTGCGATGTGC GGGCTCCTGGCAGACCCTGGGGTTCCGCTGCTCGTTGCCATGGCTCCCGCCGGAGCGGCC AGAGCGGGCGTCGGGTTGGGTGTCAGCGGTATTCCGGGCCCGGTTCTCCACCCAGGCCTG GACCTGGACCCTCGGGCACTGCAGCGTCCGTCTGTAGGTTTCCAGGCAGAGGAAATCCTG AGACATCCAGGCGCAGCTGGGAGTTGCTACCTGGCTCCATCCGTGAGCACAGCGAGGTGC TGTCTTTCATGCTTATCTGTCTTCCTCTTGAATTCAGATTCCCAACCTGCTGAGCATCCG CACACCCACTCAGGAGTTGGGGCCCAGCTCCCAGTTTACTTGGTTTCCCTTGTGCAGCCT GGGGCTCTGCCCAGGCCACCACAGGCAGGGGTCGACATGGCAGAGACACTGGAGTTCAAC GACGTCTATCAGGAGGTGAAAGGTTCCATGGTGAGAATGGCTTGGACAGGTGATACAAGT AGAGAGAAGGAAGGAGGGTAGAGTTTTTGTCCATTAATGAGAGCTTGCTTTGGTAACGTT ATTTTGGAAAAAGAAGACTCAGTATAATGTGTACCTAGTGTCTCCACCAACTCAAGGCAA TACTGAGAGATAGTCTCAGAGTTATAGGGACCGTATATGCTGTTCAGTTCCCAATTCCTG TTTTACAAATGAGGAAACTGAGAATCTGTTAAGGGTTCTAGATACCAGAGTCTGGTTTAG AATCTAGACTCCTTGGCACCCTCAGCTGTTGCTCCTGCATTGATAATCTGGCCAGTCCAC TTGCAGCAGGAATGTGTGTTAGGTAGAGCTGTAGAACCCAGGACATGCTGTGTACTGTCT CCATGCATCTGGGCCTGCTTTTCTTACAGAATGATGGTCGACTGAGGTTGAGCCGTCAGG GCATCATCTTCAAGAATAGCAAGACAGGCAAAGTGGACAACATCCAGGCTGGGGAGTTAA CAGAAGGTATCTGGCGCCGTGTTGCTCTGGGCCATGGACTTAAACTGCTTACAAAGAATG GCCATGTCTACAAGTATGATGGCTTCCGAGAATCGGTGAGATGTCCCATGGCTATAAGCC TCCTTTTTACTGCATCTTCTTATTTTAATCTTCTAGAGACTCGAGGTTCCTTCCTCATGT AACCCTGTGATTGCTAGTTTGGGCTCCTTAGAGCAGGGCTGTGAGGCCATCAGGCAATCA GTGTTTGGCTTTGAGCGTTGAAGTCTTGTGAATTTCTGTGTGCCTTGACTCCAGAAGATT TTCTTCTGTCTTGATTTAGATAGTAGTTTCTGCCTGTGGCTTTTATCAAGGTTCAGAATC TTAGCTTGATTTCTTTGTGTGTATGTGTGTTTTTGGTTTTTTTTGGGGACAGGGCCTTGC TCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGATTACTGCAGCCTCCGCCTCCT GGGCTCAAGTAATCCTTCCATCTCAGCCTCCTGAGTATCTGGTACCACAGGCACATGCCA CCATGCCCAGCTGATTTTTAATAATTTTTGGTAGAAACGGCGTTTTGCCACATTACCCAG TCTGGTCTTGAGCTCTCAGACTCAAGGGATCGCCCACCTTGGCCTCCCAAAGGGTTGAGA TTACAGGCGTGAGCCATTGCGCCTGGCTAGCTTGATATCTTAAAGTGTGGGTTTTGTTTT CCTTTTTGAACTGCTTGAGTTAAAGGCTTTATTTGATTTTAATTTCCACTTTCATTAAAG TAATACCTATACAAAGTTTATAAAGTCAGATGGCCCGTAACCAGGAATGTCAGATCCAGT GGCTAGAAGCAATCTCTTTCAACAATCTTACCATGAGCTGGGTTGCTAAGTCAGCATGGA TTTCTTATAAAGCCTATTTGGGGCAGTTTCTCAGAAATAGATAATCCCAGGACATTCAAG TCGGTGTTAAGGCCACCAAGGTTTACTGGGATTGTGCTTTCTTCCCTCCACCCACAGGAG TTTGAGAAACTCTCTGATTTCTTCAAAACTCACTATCGCCTTGAGCTAATGGAGAAGGAC CTTTGTGTGAAGGGCTGGAACTGGGGGACAGTGAAATTTGGTGGTGAGTCCTGGGGAAGA CTGAGGTTTGGGGAGGAAGATAGGGTGAAGGGTTTCAGCCTTTTACTTGTTTTGCTCTTT TCCCTCTGCCACTGTCTCTGGTTTCCTATCTATTTGCATGTTCATCATGTGTTTATTGAG TACCTACAGTATACTGCCTGGGGTTGGGGTTATAGTCTAAACAGACTAACCGCAGTATCC TGTCTCTGTGGAACTCAGTTTGGTGGGAATATTGCTTATGCAGACTTAAGGGGAGGAGCT TGTGGCTGGATAAGCCCTTTCCTCACAGGGCAGCTGCTTTCCTTTGACATTGGTGACCAG CCAGTCTTTGAGATACCCCTCAGCAATGTGTCCCAGTGCACCACAGGCAAGAATGAGGTG ACACTGGAATTCCACCAAAACGATGACGCAGAGGTGTCTCTCATGGAGGTGCGCTTCTAC GTCCCACCCACCCAGGAGGATGGTGTGGACCCTGTTGAGGTGAGGCTTCCCCTGGTTGCC TTGGCAGCAGATGGTGCTGAGCAGGCATTGGCTGGCCTGGGAGCAGGGCCTGCTGCTTGG CTACCAATATGTGCTTTTGCAGGCCTTTGCCCAGAATGTGTTGTCAAAGGCGGATGTAAT CCAGGCCACGGGAGATGCCATCTGCATCTTCCGGGAGCTGCAGTGTCTGACTCCTCGTGG TCGTTATGACATTCGGATCTACCCCACCTTTCTGCACCTGCATGGCAAGACCTTTGACTA CAAGATCCCCTACACCACAGTACTGCGTCTGTTTTTGTTACCCCACAAGGACCAGCGCCA GATGTTCTTTGTGGTAAGCAGAAACCCCTATGGCCGGATAATCCTGGTTTTTGCCTAAGT GTTAAGTAGATGGATCTCACTGGTGTGCAGAATTCTACGTTGGTTAATTGCAAGTTGTTG TAGAGTGTCAATTAGTACTCTTCCTTACTAGATCAGCCTGGATCCCCCAATCAAGCAAGG CCAAACTCGCTACCACTTCCTGATCCTCCTCTTCTCCAAGGACGAGGACATTTCGTTGAC TCTGAACATGAACGAGTGAGTGTCTCCCTGGACTCGTTTCCTACCACTGTCCAGGCAGGA GACAGGTGTGCCATTAGAAGGCAGTAGTGTTGTGACCTCACCTTGCTTTCTTTGTAGGGA AGAAGTGGAGAAGCGCTTTGAGGGTCGGCTCACCAAGAACATGTCAGGATCCCTCTATGA GATGGTCAGCCGGGTCATGAAAGCACTGGTAAACCGCAAGATCACAGTGCCAGGCAACTT CCAAGGGTGAGAGTGTGGGCCTGGGATCCTGCCCTGCCTGGGTATGGGAAATGCCGTGTC TCCTTGGTAAACCCTTCCTGAGATGGGAATGCGGCCTCCTAGAGGCCTGGATGGGACCTT GTGTCACAATAGGTGCCAGCGCCTCTGTCAGAACAGCTCAGTGAGGTTTACTTAGTCGAG GACATGAGCACTCGTGTCGCTGCTGCTAGATACGCCCTTTGCCTCTGCTGAGGTTGGCAC TAACCAGGCTCCCTGCACCCTCTGTCAGGCACTCAGGGGCCCAGTGCATTACCTGTTCCT ACAAGGCAAGCTCAGGACTGCTCTACCCGCTGGAGCGGGGCTTCATCTACGTCCACAAGC CACCTGTGCACATCCGCTTCGATGAGATCTCCTTTGTCAACTTTGCTCGTGGTACCACTA CTACTCGTTCCTTTGACTTTGAAATTGAGACCAAGCAGGGCACTCAGTATACCTTCAGCA GCATTGAGAGGTGAGAACCTCCACCTGTCACTTCCTGGGCATCCTGGTCCCGAGCCAGCT TTGTCTAGGAAGGCTGGCGTGGCCTGGGGCACTCTCCAACCCTAGAGCAGAATTTTTCTT TTGCTACATCAGGATTTGGTCCTTTTCCCTGGAGTGCTCAGACTTTAGAAACCTCTCCAT TGCTTTCTTTCTGGTCATTAAAAAAACAAAACAAAACAAAACAAAAAAAACTTTTTCCGT ATTCTGAAAGCTATATGTCTTCGCTACTGGTCTTTTTTCTCCTCCACTCCCCACCATGAT GGAAATGCTATCTCTTTCTTTCCTGGAATGAGCTTTGTGCCTGAGAACATAGCGGCTAAT GCTTATTGAGTGCTCACTGTGGACTAAACGTTTTATAAGCATCTTCACGTGTAATCCTCA TATCAACCTTGTGAAGTATGAAAAAAGATGACCACGTCCCCTGCCCCACACTTACTCCCC TCTGAGCTTATTTTGTAAACAGATGCGCACCCCTCCCTGCCTTTCCTTTCCCAGAGTTCT TCAAAGCCATGCAGTTCTTTCAGGACTAATGTCTGGCTCTGGCTCTGCCTTACTGCTGTC CTCTGGGGGTTTCTAAGCTGTTGGGTTGGGTAGCATAGTCAAGAGCTCCAGGCTCCACAG TCTACCCCAGCTCATGGAATCAGAACATTGTTTAGTGTGCCCCTGTGTTGGCACTACCTC TCTGGTAACATGGTGCATGTCCCCTCACAGGGAGGAGTACGGGAAACTGTTTGATTTTGT CAACGCGAAAAAGCTCAACATCAAAAACCGAGGATTGAAAGAGGTACTTCTGTGTGGGGA GGATGAGACCCTCTCCTGGTCTTTCTATAGGGGAGAAAGGGGTGGAGATTTTTTCCGGCT TCTTTTTCACTCTTTCTTCTCTTCTTACCCTTATAGAAAAAAGAGGTGCGTGTGACCCTT TCCCCCTCCTGGTGCAGGTTTCCTCTGCATGACCTTAGACCAGTCTATGCAGCCCCTCAG GAGCCCCCAGTGGGGCTGGGAGAGGGAGGGGCTTGGGGCTTGGACTAACCCAGTTGGCAG GAAGTACTTGGGCATAGGCCCTGCACGTTGGCTGTGTGTGGACAATCCAGCCCCAGGTCT TCTGGGAGCTGCTGCTCTGACTTGACAGGCATGGGGGTGTGCTTTTGAGTGTGCAGGGAT TCTGGCTCGAGGGTGAGTTGGCCCCACCGTGAACTCTTCCCTGGCTAGGGCATGAACCCA AGCTACGATGAATATGCTGACTCTGATGAGGACCAGCATGATGCCTACTTGGAGAGGATG AAGGAGGAAGGCAAGATCCGGGAGGAGAATGCCAATGACAGCAGCGATGACTCAGGAGAA GAAACCGGTGGGTTAGCCTCCGTGCTGAGCACGAGGATGGTCAGACGCTCCTCGCTGTGG CCCGGGCTGGACTCACCCTTGGGCCAGAGCTGGGTGCCTGGGTGAGGTGGGGGGATTTCC ATTGGGGCAGAAGCTGATGCATCCTGTGCCCTTTTTCAGATGAGTCATTCAACCCAGGTG AAGAGGAGGAAGATGTGGCAGAGGAGTGAGTTTTGGTGGTACCTTGTGGGGATAAGATGG TGACCCATAAGCTTAAGGGACCAGAAGATTTCTGGACATTTCTCAGGTCCCAGCATTAGC TACTGACCCAGAATGGGAGAGTGACCTCCAATGAGGTGATATACGAAAATGTTTTGGAAA TTGTCAAGGGCTTTGTAAGTGCAAGACATATTTTGAAGTCGGAAAAGTATAGTGGGATCT ATGGCCATACCGCCCTGAATGTGCCAGTTGGGGCTGGTTCGTAGTTGGATGAGGAGAGAA TGGGAATGAGCTGGTGCTTGCCACTTACTTGCTGGGGGTTGTCGAGTAAGTCATTGAATC TCAATTTCCTCATCAGTAGAAATGCAGTAGTACCCCTGCTAAATTGGTTAAGACTTTTTG TTAGCAGTGTCAGAAATGTGATTCACTCTCACTTTAAAAGGGAACATATAAAAGGGAATT TCATAAGTTCATATTACTGCGGAGTCTGGGGATTTAATTGGCTTCAGACACTACTGGATT CAGGCGCTCAAATCTATTTCTTCCGATTTCCTTAATTAAAAATAGGTTTACCCCATGGGG TGCCCAGTGACTCTCAGAAGCTCAGGGCAGGCTTAATCCTACTGGTTTAAAACAACACCA GAAGTGCCTCTTTTGGTGAACAGCATAGTGAACACAGTGGTTACCTGCCCCTTTCTAGCC TGAGTTATTAGAATGGGCTGGGGTCTGATGGGCCAGAAATAGGCCAAGTGCCCACCCTTA GAGCCTGTGGTTGGGGTAAGCCCTTCCTGAGTGGGGGCAAGGTGGTTCCCAACAGAAAAT TGGGACTCTGCTCTCTTAATCCAGAAGGATTGTAAAAGAATGTCGGGCAGCAAAAAAAAC ACCCAACAGGAGTCCTCTAGTTCAGCCTGCCACATGCTTATGAAGGTTTATGAAGGTTTA ATGAGCAAATACTTGTGAAAGTGCCTTGAAGACTGTCCAGCAGCATACAGGTGTAAGGTA GTTGCATTGTTTGAGGAGTTTCACATATATCAGACAAGACTGTCAATTACAGGGGTAGGC ACTGGGTTGGACTGAAGTTGGTTTTCCTCTTTTTGTAGTAACTGATTATCTTTTCATCAG AAGACTGTAGGGGCCAATCCTTTTGTAGTTCATAAACATAATGGTTGGGTGTTACGTGCG TGTGTGAAATGTGCCACCCTCCAGCCTTGTTACGATGTTGACACATTACCCATCTGACAT GGAAAAAAAAAGAAGACAAAAAAGACTATAGGGTAGATTAAGGTGATTACTCCGAGGGAA GTGGTGAAGTGGATTTGGGCCATGTTCCAGGCATGAATGAGGCAGTGTTTCTGCCAGTGG TGTCCTGGGGATGGACTAGGACCTGGTTTGGCCATGCCCAGGGAGATCCGCTGAAGCTCA TTGATTTGTTTTTCATTCATTAATTCCAATCAAGTAACCAATTGCTGTGGCTGGGTCTGG AGAGGGCATGGCTGAAGCCACCACAGTGAATGGGAGAAAGCAGTGTTGGGGATTGGTGGT GGATACTGTCCTCTGGTCTTCCTCCCTTGCCCCTTTTGGGTGGGTATCTTTGGATTTGTC TTCCTCCTGTCCTGAGGCCGTGGGGTCCTGTCTTCCCTCCTCAAGTCTAAGCCTGGCTTG TTCTCTGGCAGGTTTGACAGCAACGCCTCTGCCAGCTCCTCCAGTAATGAGGGTGACAGT GACCGGGATGAGAAGAAGCGGAAACAGCTCAAAAAGGCCAAGATGGCCAAGGACCGCAAG AGCCGCAAGAAGCCTGTGGAGGTGCAGACTGTAGATGGGAGGGCCTGTGTGTGGTGCAGT GGGTGGGGGGCGTGGGAGGCATTCTCTTTACCTTCTCCTGTCCACCACCAGTAGGACCTG TTCTTCCTTGGGGCTGTTTTTTATAGCCAGTGATTATAGCCTTGAGGGTTATCTTCTTGG AAATTTTTCTCACTAGCCCTGAGATTAATAAGCTTCTGGAAGGTCTGAATTAGGAGATGG GCTTCTGTCCTGGTAAGCTAGGCACTGAATTGCAGAGGGGAAGGAGATACTATCCTTGCC CTTAGGGAGCTCTCGTCTCGCCTGATGCTATTTAGTCCTCCACTTTTTCTCCAAGTTAAG TGATCTAAATAATTTATTTGGGAAAATGTATGGGTTCTGTGGGAAATAGCTGAAGGCATT TGGGTTCTTATGTAGGTGAAGAAGGGCAAAGACCCCAATGCCCCCAAGAGGCCCATGTCT GCATACATGCTGTGGCTCAATGCCAGCCGAGAGAAGATCAAGTCAGACCATCCTGGCATC AGCATCACGGATCTTTCCAAGAAGGCAGGCGAGATCTGGAAGGGAATGTCCAAAGAGAAG AAAGAGGTGAGTAGCAGCAGAGGAGGGGTGATGCCTCTCATGGGCTGGCGAGAGGTGCTG TCTTGGGGTGGCGAGTCTCATGACTGATAGGGGAGCAGTATGAGCCATTGGTGGGACTTT CTGTATCGATTTTGCCTGCATCAGGGGAGAGGGGAGATGGGAGAGGTCTTATTCTTAACT GTTTTTTTCTGTGTGTGAGACAGGAGTGGGATCGCAAGGCTGAGGATGCCAGGAGGGACT ATGAAAAAGCCATGAAAGAATATGAAGGGGGCCGAGGCGAGTCTTCTAAGAGGTGAGTGT CGAGAACATGGCCCAGTCACTGATTTTTGTGGCAGACTTTTTTTTTTTTAACAGGCCGAA GTTGAGCATTGGAAAGTTAAAGACAGCAGAGATGCTTCTGACTGCAGTAGGGTAGTGCTT CTCAAACCTGGGTAGGCCATTGCCCAAGTATGGGTGACACAATAGGGCATTCAAGTCACT GGGGAAATATGGCCTCTTTTCCTGGACCATTTTATTTGAAGGTATGGGGGAACGAAAAAA ATACTATTATGGAGTGCAGTGCACAGTTTGCATGAACTCTAAAAGATAAAGCAAGAAATA TCAAGTAGGTTTTGCACATTGGGCTGCTTTAGGCTGTGCCCTCTGATTCTTCTGGTGTAC TCATGATACTCTCCCTTGGTGCCCTCCAGGCTGACGCAGCTATTTACGTTCAGAGTGAAA TGGGCTGTGTGGCTGGGATTGGGAAAGGCCTTGTTAAAGCTGGGAGAGGTTTGGTCATGG TGACAGGGGACCTGAAGGCCCAGCTCCTCTTCCCTCTTGCCAATACAGGGACAAGTCAAA GAAGAAGAAGAAAGTAAAGGTAAAGATGGAAAAGAAATCCACGCCCTCTAGGGGCTCATC ATCCAAGTCGTCCTCAAGGCAGCTAAGCGAGAGCTTCAAGAGCAAAGAGTTTGTGTCTAG TGATGAGAGCTCTTCGGGAGAGAACAAGAGCAAAAAGAAGAGGAGGAGGAGCGAGGTGCG GCAGGAATGTGGGGCCTGTGGGCTGGGCAGGGTGAGGGGCATGTGTGTCTGTGTGGGGTT GGTCTGTAAGAGTAATGAGTTGGAGTGGATGGTGGAATTCTGAGGTTCTGAAGGGGGGTG CTGTAGTTGGGGGCGGTAGGGAATTGCGGGCCCTTCACTGAAGAGTGGGTGGGGCACCCA GGACTCCAGCTTTTCCCTTAAGACACCTTTGGTTTTCAGGACTCTGAAGAAGAAGAACTA GCCAGTACTCCCCCCAGCTCAGAGGACTCAGCGTCAGGATCCGATGAGTAGAAACGGAGG AAGGTTCTCTTTGCGCTTGCCTTCTCACACCCCCCGACTCCCCACCCATATTTTGGTACC AGTTTCTCCTCATGAAATGCAGTCCCTGGATTCTGTGCCATCTGAACATGCTCTCCTGTT GGTGTGTATGTCACTAGGGCAGTGGGGAGACGTCTTAACTCTGCTGCTTCCCAAGGATGG CTGTTTATAATTTGGGGAGAGATAGGGTGGGAGGCAGGGCAATGCAGGATCCAAATCCTC ATCTTACTTTCCCGACCTTAAGGATGTAGCTGCTGCTTGTCCTGTTCAAGTTGCTGGAGC AGGGGTCATGTGAGGCCAGGCCTGTAGCTCCTACCTGGGGCCTATTTCTACTTTCATTTT GTATTTCTGGTCTGTGAAAATGATTTAATAAAGGGAACTGACTTTGGAAACCA OMIM ID 604328