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Gene information for SRP72 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6731
Official gene symbolSRP72
Full namesignal recognition particle 72kDa
Aliases,-,
Gene summaryThe SRP72 gene encodes the 72-kD subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of proteins to the endoplasmic reticulum (ER) (summarized by Lutcke et al., 1993 [PubMed 8388879]). The complex consists of a 7S (or 7SL) RNA and 6 different proteins, SRP9 (MIM 600707), SRP14 (MIM 600708), SRP19 (MIM 182175), SRP54 (MIM 604857), SRP68 (MIM 604858), and SRP72. The proteins are bound to the 7S RNA as monomers (SRP19 and SRP54) or heterodimers (SRP9/SRP14 and SRP68/SRP72). SRP9 and SRP14 constitute the Alu domain of 7S, whereas the other 4 proteins belong to the S domain. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein.[supplied by OMIM]
LocationChromosome: 4   Locus: 4q11
Gene position57333762 - 57369847  Map Viewer
Gene orientationplus
Gene size36086 bp
Gene sequence