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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SOD1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6647 Official gene symbol SOD1 Full name superoxide dismutase 1, soluble Aliases ,ALS,ALS1,IPOA,SOD,homodimer, Gene summary The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq] Location Chromosome: 21   Locus: 21q22.1|21q22.11 Gene position 33031935 - 33041244  Map Viewer Gene orientation plus Gene size 9310 bp Gene sequence >SOD1:18693806..18703115:Length=9310 GTTTGGGGCCAGAGTGGGCGAGGCGCGGAGGTCTGGCCTATAAAGTAGTCGCGGAGACGG GGTGCTGGTTTGCGTCGTAGTCTCCTGCAGCGTCTGGGGTTTCCGTTGCAGTCCTCGGAA CCAGGACCTCGGCGTGGCCTAGCGAGTTATGGCGACGAAGGCCGTGTGCGTGCTGAAGGG CGACGGCCCAGTGCAGGGCATCATCAATTTCGAGCAGAAGGCAAGGGCTGGGACGGAGGC TTGTTTGCGAGGCCGCTCCCACCCGCTCGTCCCCCCGCGCACCTTTGCTAGGAGCGGGTC GCCCGCCAGGCCTCGGGGCCGCCCTGGTCCAGCGCCCGGTCCCGGCCCGTGCCGCCCGGT CGGTGCCTTCGCCCCCAGCGGTGCGGTGCCCAAGTGCTGAGTCACCGGGCGGGCCCGGGC GCGGGGCGTGGGACCGAGGCCGCCGCGGGGCTGGGCCTGCGCGTGGCGGGAGCGCGGGGA GGGATTGCCGCGGGCCGGGGAGGGGCGGGGGCGGGCGTGCTGCCCTCTGTGGTCCTTGGG CCGCCGCCGCGGGTCTGTCGTGGTGCCTGGAGCGGCTGTGCTCGTCCCTTGCTTGGCCGT GTTCTCGTTCCTGAGGGTCCCGCGGACACCGAGTGGCGCAGTGCCAGGCCCAGCCCGGGG ATGGCGACTGCGCCTGGGCCCGCCTGGTGTCTTCGCATCCCTCTCCGCTTTCCGGCTTCA GCGCTCTAGGTCAGGGAGTCTTCGCTTTTGTACAGCTCTAAGGCTAGGAATGGTTTTTAT ATTTTTAAAAGGCTTTGGAAAACAAAAATACGCAACAGAGACCGTTTGTGTGACACTTTG CAGGGAAGTTTGCTGGCCTCTGTTCTAGGTCATGATTGGGCTGCAAGGGCAGAGAAGGTA GCCTTGAACAGAGGTCCTTTTCCTCCTCCTAAGCTCCGGGAGCCAGAGGTTTAACTGACC CTTTTGGGGATTTTTGAGGGCAGTGATCTTAACTTTGGGTGCACAGTTAGCTTATTTGAA GATCTTACTAAAAATACACCAGAGCCCAACCTCCGACCAATTACATCAAAACCTGTCCTA GTGCAGGGTGAGTATTGCTGTTTTTTGAAAGTTTCCAAAAGTGATTTTGATGTGCACCTA CGATTGAGAACTGTCGTTTGAGGACAGTGGGTGGAGTTTCGTATTTGGAAATTAGAAGAC CTGGAGTTTCCATTACACCGAATTGGCACTTAATAACTGTTGTCGGAGCATTTCTTAAGC CACATTTTCGTAAAGTGGCTTTAAAATTGCTCTGCCAGTAGGCAGGTTGCTAAGATGGTC AGAGACAAACTTCTGAACGACTCTTGTAAAATATACAGAAATATTTTCAGAACTTTTATC AGTAAAATTACAAAACGTGTTGCAAGGAAGGTGCTTGTGATAACACTGTCCCCAGAACCT TAGTGAAGTTACCAACTGGTGGAAAATTTTCTCTTGCACTCGGCTTAAAAATCATGAGGG AATATTTACTATACGAATGAGATTCAGTCTTTAAAGGGGTTTACAGAAACGTGAGAGGAC AGGAACAGTTAGTCTGTGTAAATGTCTGAAATATATGTGAGGGAGATAATGAGTTTAGCC TTTTTCTTTAATAGGTCTCCAGATTTTCTGGAAAAGGTTCTTTGGCATTTGACTCCATTT TGCTGTTTCATTTGTCAGACTTCTTTTTGTCCCTCTTTACTTCTCCCCACATAATTCACC AGTACTAGTGTTTTGTTTTTCAGACCAAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGT GGCGCGATCTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCA GCCTCCCGGGTAGCTGGGACTACAGGCGCGCGCCGCCACGCCTGGCTAATTTTTTATATT TTAGTAGAGACGGCGTTTCACCATGTTGGCCAGGATGGTCTCGATCTGTTGACGTCGTGA TCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCCCGCCCGGCC ACCAGTGCTATTCTTAAGACGCCTCTGAGGAATCCCTTCTCCCTGGCCATTGAGAATCCA TGCATGAACCCAGGTTTTCCACCTTCCCTGAGCAGCTTGCATAGTTCCTTCTTTTAAGCG CCTGACTTCGTTTTGTTTGGTGCCCGTTGTACCTGAGAATGAGCCTTGGATAGTGGAGCA TTCCAGCTTTCCAGATATGCAGAGATAATACATTGGCTATCAGCTACTTGGCTTGGCCTA TTCCGTGTTTAAAATCTTGGACTCTTTGCTAGTTTTTACAGATCAGAATTTTTCACGTAT TAATCCAGTTTTCCTAGCTTCTCTTGAAGAATTTTTGGAGATCTCTTCATACTGAGCCTT CATTAGCCCAGGACAGTACTGCTGTAGCAGTTCATATATTTTTTCGCTTCCCAGGCCTGT GTTATTCACTTAAGTTCATAGCCTGGTCCCTGCAGGGTTGTACCCGAGCACAGCTACTTA GATGTCCTGAATGTATTACCGGTTAAATGGAGGTTTCAAAGAACCTGCTGTTTTTGGCCC TGTGCTCTTGATAACAGAGTGTTTGAGGGACAACTTTCACATTTGAGTTTTTCCAAAATT AAAGGTTGTAGAAGAGTCACAGTATCTATTGTCAAAAAGAAAAGAATTTAAAAAGGCAGC AATTGCCAGGATACTTCATTTGAGCAATGATATTTTCCAGTGGAAAGTCACATCTTAAGG GTTAATGCCCCTTAACTGTTGGCCGTATTTGAAAACAAACCAAGCTAAAAACAAGAGACA CTGACATGTTGTATGACGGTGTGGTGTGGATGTTGTGTTTATTTTAGTCCTGAGATCTAG TTGTAACTTCCTTGATTTCTGTATGTAGCCACGGAGCACCATTACCTGTCACCATTACCT GAATGGCTATACTGCTTGCTTTCATTTTGGTAGAGTGGAAAGGTTACCTAGGTTTCAGTG CTTGAAAAGATTTCAGAAAGCAGTAGTACGTCTGGTTAGACTAGAATCAGTCCTCTCCTG GGGGCAGTGGAATATAATATTTTCTGACTGCTAATTAAAAATACCTGTGATAGCCGGGCG TGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGTGGATCACGAGGT CAGCAGATGGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATGCAAA AAAATTAGCCGGGTGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCA GGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATCATGTCACTGCAC TCCAGCCTGGGCGACAGAGCGAGACTCGTCTCAAAAAAAAAAAGAAAAAAACTTATGATG GACACTTAAAAACACTCACTGAGTGGGGAGTGGAGAGCAGGGGTCCCAGGGTAGCCTGTT GGACATTTCCAGGGCGACTTTTTCTTTTTTTTTTTTTAAAGTCAAGTGAGTATGCCATAT GGAAAAGGGTGTGCGTGGAGAAAAAGCAAGGGGCTCCAGAGTGTAGGATGAGACATACAC CTTTTGGGTTAAAAAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCA GTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTTGTCTCA AAATAAAAAACGTTTACATGTACATGTATATTCAACATGTACAAATATAACCTATTCAAA AGTATTTACTACATAAATAGGTACTTACATTACCTATTTACTGTAATAGTCAAAGCCTAT GAAGTATCTAACACTGATGTGTAGGTACTCACTTTGCTTGCCACTCTATTAGGTGCTTTT TATGTTATTTAATCATGAAGCCTGGCCACAGGGTGCTTGTGCATTGAGTGTGGGAACAAG ATTACCATCTCCCTTTTGAGGACACAGGCCTAGAGCAGTTAAGCAGCTTGCTGGAGGTTC ACTGGCTAGAAAGTGGTCAGCCTGGGATTTGGACACAGATTTTTCCACTCCCAAGTCTGG CTGCTTTTTACTTCACTGTGAGGGGTAAAGGTAAATCAGCTGTTTTCTTTGTTCAGAAAC TCTCTCCAACTTTGCACTTTTCTTAAAGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAG CATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATAC AGCAGGTGGGTGTTGTGCTGTGCTGGTGACCCATACTTGTTCACCCTAGTTAGATAAACA GTAGAGTAGCCCCTAAACGTTAAAACCCCTCAACTTGTTTTTGTTTTTGAGAAAGGGTCT TGCTCTGTCGCTCAGGCTGGAGTGCAGTGGCGCTGTGCGATCATGGCTGACCTTAGCCTT GACCTCCCAGGCTCCATTGATCCTCATGCCTTGGCCCGTAGCTGGGACTACAGGTACACA CCACCACGCCTGGCTAATTTTTGTATTTTTTTCTAGAGGTGGGGTTTCATCATGTTGCCC AGGCTGGTCTTGAACTGCTGGGCTCAAGTGGTCTATCCTCCTCGACCTCCCAAAGTGCTG GGATTACATGTGTGAGCCACTGTGCCTGGGAAAACCCTCAACTTTTCTTTTAAAAAAGAG GTCAACTTTATTGTATATAAGCACTGTGCTAAAATTGCAGGAACTGGGACCATATCCTGA TTTTTGTAATAATGCCAGCAGAGTACACACAAGAAAAGTAACTGCACTAGATTGTGAAGA CTGGGGTGGACCTGCTTCTGAAGGTCCAGTGCCCTTTGTCTTAAGATTTGGTGTAGTGTG TCTTTAGAAACCAAAAAAAGAGAAGAAGATCAACCTTAAGATTAGCCACAAAACTGGGCT TTGATACCTAGGTGTGGAAAAGAAAGGGAAAGAGTTGATGTTTTGTCTTACAGCATCATT GTAGAAGAGGGTGTTTTTTTGTTTGTTTGTTTTTTGAGACGGAGTCTTACTCTGTGGCCC AGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCATGC CATTCTCCTGCCTCAGCCCCCTGAGTAGCTGGGACTACAGGTGCCCGCCACCCCGCCTGG CTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAAGATGGTCTCTC TCCTGACCTCGTGATCCGCCTGTCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGC CACCGCACCCAGCCAGAAGAGGGTGTTTTTTAAAGAAGGCAAATAGGAAATAAAAACTTG GGCTCTTAACTTTTGTAATGATCCCAGGTGTTTGAGCTGGGGGTTGAGGGTGGGTGCCTC GAGCAAAGGGGCTGCATTTATTTGCATAATGCCATGTAAGAGTAGCTCTACACCCCAAAC ACAGGCTTCTTAGTGGGACCAAAGTATGATACAAACTGAAGATGGAATGCAGAGGATTAT TGGTACTTTGGAATATGCTTAAAAAAAATTTTTTTAAAGTATTTTTAAAAAATCAGGCAA CCCCTGAACCAGAGTAGGTTCAGAGAAACTGCCAAATTTTATTTTCTTAATTTGGGATTG GAAGCAAGTTAACAGAAGTTTATGAGTTAAGTTGCATTTAGTGATCTTTTGCCATATTTG AGTAATAATCTGATTTTTTTGTTTATAGATTTCTTCTTAAATTAACTTTATTCATCTTGC TAATTTAGTTTCAAATAGTGATTTGTAATGATCAGATTTGATCCATTTCTGTAATTGCTG AAATTCCCCCGAGTTGCTTTTTGGCTTTACCGCCTCTGGTCTGGGAGGTGATTGCTCTGC TGCTTCCTGTAACTTGCCTGCCTTTCTCCCTGTGTGGGACTCCTGCGGGTGAGAGCGTGG CTGAAGACAGCCGTGTTATGAAAGGGCCTCCTGTGCTGTCGAGGTTGTGCTCTGTGAATG TCATCCCCTGGTGCACAGCAGCACCTTCTACACAGGATACAGTTGGAATGCCGCCCCCTC GAGTTGTGTAAGGCAGCAGCCTTGGCCCTTGCACATAAGATGCTGTTGAATATTCTGCCT GCACCAAGTAAAGGGCACAGATAGAACTGCTTGGCATATGTTGCTGGGGAGATGAGTTTT TTGTAAAGTATACTACGTTCTTAAGAATTTGGATCATAACCATGGGATTTTAATAATAGA AAAACTGTTGAAGATCAGTCTGGTCCCTTATTTTTACAGTGAAGAAGCCAAAGCCCAGAG AAGGGTGTTAACTTTACAAGTGTCAGACAGTAGTTAGAACTTGGTGGGGTTTTTTTTTTT TTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTCA GCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTACTAAGTA GCTGGGACTATAGGTGCGCACCACCACGCCTAGCTAATTTTTGTATTTTTTCAGTAGAGA CAGGGTTTTGCTATGCTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGATGATCCAGCCA CCTCAGCTTCCCAAAGTGCTGGGGTTCCAGGTGTTAGCCACCATGCCTGGCCATAGACTT GTTTCTGTTCCCTTCTCACTGTGGCTGTACCAAGGTGTTGCTTATCCCAGAAGTCGTGAT GCAGGTCAGCACTTTCTCCATGGGAAGTTTTAGCAGTGTTTCTTTTTAGAATGTATTTGG GAACTTTAATTCATAATTTAGCTTTTTTTTCTTCTTCTTATAAATAGGCTGTACCAGTGC AGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGTA ACAAGATGCTTAACTCTTGTAATAATGGCGATAGCTTTCTGGAGTTCATATGGTATACTA CTTGTAAATATGTGCTAAGATAATTCCGTGTTTCCCCCACCTTTGCTTTTGAACTTGCTG ACTCATCTAAACCCCTGCTCCCAAATGCTGGAATGCTTTTACTTCCTGGGCTTAAAGGAA TTGACAAATGGGGACACTTAAAACGATTTGGTTTTGTAGCATTTATTGAATATAGAACTA ATACAAGTGCCAAAGGGGAACTAATACAGGAAATGTCATGAACAGTACTGTCAACCACTA GCAAAATCAATCATCATTGTGAAACATAGGAAGCTTCTGTAGATAAAAAAAAAAATTGAT ACTGAAAACTAGTCGAGACTCCATTTATATGTGTATGTTTTCTGAAAGCCTTTCAGAAAA ATATTAAATTTAAGGACAAGATTTTTATATCAGAGGCCTTGGGACATAGCTTTGTTAGCT ATGCCAGTAATTAACAGGCATAACTCAGTAACTGAGAGTTTACCCTTTGGTACTTCTGAA ATCAGGTGCAGCCCCATCTTTCTTCCCAGAGCATTAGTGTGTAGACGTGAAGCCTTGTTT GAAGAGCTGTATTTAGAATGCCTAGCTACTTGTTTGCAAATTTGTGTCTACTCAGTCAAG TTTTAATTTAGCTCATGAACTACCTTGATGTTTAGTGGCATCAGCCCTAATCCATCTGAT GCTTTTTCATTATTAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTG TGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTG GCCGCACACTGGTGGTAAGTTTTCATAAAAGGATATGCATAAAACTTCTTCTAACATACA GTCATGTATCTTTTCACTTTGATTGTTAGTCGCGGTTTCTAAAGATCCAGATAAACTGTA CTTGCAGTTCAAATTAGGAAAAGCAATTTTATTGGACAATTACGGTGAAAATGAATTATT TTATCTAGGTCAGTTAAGAACACTGTTCTGCTAAGATGCAGTAAAAAGCAGGTTACATTT GACCATATTAGATCTGAGTTTGGAAAACAGAAGTAGTCTTTAGTTTTAAAATGGCCAGAT TTTCTTGCCAGGATTGGGTTTCTCACTTGTTAAACAGAACATTTTGTTAAGTTTAAAACC TGGGATGGACTTAAGTATTCATGTTCATTCATGTTCATTCAGGACTGCAGGTTATCATGA CTTGTTTAACTTGTGGGAAGCTGTTGTCCCAAGTTATCCTGGGGAACTGCATCTGGTTCT TGCAAAACACCAAGTAGACAGGCTCTCTTTTACCTCCCCTTGAGGGCATTAACATTCAGT AGTCACTTCCATTCAGTTAACCCTTTATTTTTATGGTTTTTCTTGAGCCATAGTTGTAAA GCAGAAAAATCATTTATAAAGGTTTGTTGAACAAAATTCAAAATACTGTTGCTTAAAGTA TTAAGATTTTTTAGGATTATACCTTACTTATAGGCCCGTCATTCATTTGGCATGAAATTT TGAGTTTTATTCACTTTCACTTTCCTTTTTTTCCAAAGCAATTAAAAAAACTGCCAAAGT AAGAGTGACTGCGGAACTAAGGTTACTGTAACTTACCATGGAGGATTAAGGGTAGCGTGT GGTGGTCTACAACATAGTTATTTGGGTTTTAGTATTTCATTTAGACAGCAACACTTACCT AATGTTTAAAGGTAATGTCTTTGCAACACCAAGAAAAAGCTTTGAGTAGTAGTTTCTACT TTTAAACTACTAAATATTAGTATATCTCTCTACTAGGATTAATGTTATTTTTCTAATATT ATGAGGTTCTTAAACATCTTTTGGGTATTGTTGGGAGGAGGTAGTGATTACTTGACAGCC CAAAGTTATCTTCTTAAAATTTTTTACAGGTCCATGAAAAAGCAGATGACTTGGGCAAAG GTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAA TTGGGATCGCCCAATAAACATTCCCTTGGATGTAGTCTGAGGCCCCTTAACTCATCTGTT ATCCTGCTAGCTGTAGAAATGTATCCTGATAAACATTAAACACTGTAATCTTAAAAGTGT AATTGTGTGACTTTTTCAGAGTTGCTTTAAAGTACCTGTAGTGAGAAACTGATTTATGAT CACTTGGAAGATTTGTATAGTTTTATAAAACTCAGTTAAAATGTCTGTTTCAATGACCTG TATTTTGCCAGACTTAAATCACAGATGGGTATTAAACTTGTCAGAATTTCTTTGTCATTC AAGCCTGTGAATAAAAACCCTGTATGGCACTTATTATGAGGCTATTAAAAGAATCCAAAT TCAAACTAAA OMIM ID 147450