| Entrez gene ID | | 660 |
| Official gene symbol | | BMX |
| Full name | | BMX non-receptor tyrosine kinase |
| Aliases | | ,ETK,PSCTK2,PSCTK3, |
| Gene summary | | This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Location | | Chromosome: X Locus: Xp22.2 |
| Gene position | | 15518900 - 15574652 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 55753 bp |
| Gene sequence |
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| OMIM ID | | 300101 |
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