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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BMX (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID660
Official gene symbolBMX
Full nameBMX non-receptor tyrosine kinase
Aliases,ETK,PSCTK2,PSCTK3,
Gene summaryThis gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
LocationChromosome: X   Locus: Xp22.2
Gene position15518900 - 15574652  Map Viewer
Gene orientationplus
Gene size55753 bp
Gene sequence
OMIM ID300101