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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for WNK4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID65266
Official gene symbolWNK4
Full nameWNK lysine deficient protein kinase 4
Aliases,PHA2B,PRKWNK4,
Gene summaryThis gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.
LocationChromosome: 17   Locus: 17q21-q22
Gene position40932649 - 40949084  Map Viewer
Gene orientationplus
Gene size16436 bp
Gene sequence
OMIM ID601844