| Entrez gene ID | | 65266 |
| Official gene symbol | | WNK4 |
| Full name | | WNK lysine deficient protein kinase 4 |
| Aliases | | ,PHA2B,PRKWNK4, |
| Gene summary | | This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB. |
| Location | | Chromosome: 17 Locus: 17q21-q22 |
| Gene position | | 40932649 - 40949084 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 16436 bp |
| Gene sequence |
| |
| OMIM ID | | 601844 |
|