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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC1A2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6506
Official gene symbolSLC1A2
Full namesolute carrier family 1 (glial high affinity glutamate transporter), member 2
Aliases,EAAT2,GLT-1,
Gene summaryThis gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p13-p12
Gene position35441105 - 35272752  Map Viewer
Gene orientationminus
Gene size168354 bp
Gene sequence
OMIM ID600300