| Entrez gene ID | | 64946 |
| Official gene symbol | | CENPH |
| Full name | | centromere protein H |
| Aliases | | ,-, |
| Gene summary | | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5p15.2 |
| Gene position | | 68485375 - 68506184 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 20810 bp |
| Gene sequence |
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