| Entrez gene ID | | 64407 |
| Official gene symbol | | RGS18 |
| Full name | | regulator of G-protein signaling 18 |
| Aliases | | ,RGS13, |
| Gene summary | | This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq] |
| Location | | Chromosome: 1 Locus: 1q31.2 |
| Gene position | | 192127592 - 192154945 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 27354 bp |
| Gene sequence |
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| OMIM ID | | 607192 |
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