| Entrez gene ID | | 6175 |
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| Official gene symbol | | RPLP0 |
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| Full name | | ribosomal protein, large, P0 |
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| Aliases | | ,L10E,MGC111226,MGC88175,P0,PRLP0,RPP0, |
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| Gene summary | | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q24.2 |
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| Gene position | | 120639014 - 120634503 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 4512 bp |
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| Gene sequence |
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| OMIM ID | | 180510 |
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