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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNASE1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6035 Official gene symbol RNASE1 Full name ribonuclease, RNase A family, 1 (pancreatic) Aliases ,MGC12408,RIB1,RNS1, Gene summary This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq] Location Chromosome: 14   Locus: 14q11.2 Gene position 21271036 - 21269515  Map Viewer Gene orientation minus Gene size 1522 bp Gene sequence >RNASE1:complement(2269515..2271036):Length=1522 GTATAAGGTCCACACCCCGGGAGCTGAGTGATTGCAGAAACTGGCCTTCCATCTCTCTCA GACACCAAGCTGCAGATCCAGGTAAGCAGCCCAAGAGGTGTTCTCAGGTGCCGCTTCTGC TTCAGGGTTGCAGAAGAGGGAGCTAGGGCCAGTCCACAGCACTGAGAAAGATTGGGTGAT GCTAGCGCTGAAAAAATGTGGCCCAGGCAAACATCAGCTGGGGGCAGAGGGGTCAGGGTG GAACGTGCAGGCTGCAGAGCATCCATGGGACTGGAGAAGAAGGAGCCTCCAAATTGGGGG AGGCCAGCGTTTCTCTCTGGAATACAATGGAATCTTTTATGATGCCAGTGTCAGGCACTG GCCTGAGTTCCCTTATGCTCCAAGACAACAAGGCTCTGTCACCCATGGCCCTGGATGTCG GGGATACAATTTGGTTCATGATTTATTCAAACTGATGTTTCGATGAGCCATTTGAGCACT GGGTACAAATGTATTTTGGATCAAAGAAACTCCAGTATTCAAAGATAGGAACTGACAGGA TTTTAGGTCACTTTGTAGGTCACCACCTAGAGGGGAGGAAGACCTCGCTTTGGAGAGTGG GAATAAAACGCTCGTGGAAAAGGGTACACGTGAGTGTCTCATTACACGAAAAACCTCAGG AAGTAGGATGGACGTCTTTCTGGCTGACCTGAAACAGAAAGTGTAAACCAGGCAAGCCAT AGGTGGGAGCTGGAGTTCTTTTTCTAAGAGGGCTCTTTTCCTTCTCTCTCCTTTTCTCAA TTAGGCTTTTCTGGGAAAGTGAGGCCACCATGGCTCTGGAGAAGTCTCTTGTCCGGCTCC TTCTGCTTGTCCTGATACTGCTGGTGCTGGGCTGGGTCCAGCCTTCCCTGGGCAAGGAAT CCCGGGCCAAGAAATTCCAGCGGCAGCATATGGACTCAGACAGTTCCCCCAGCAGCAGCT CCACCTACTGTAACCAAATGATGAGGCGCCGGAATATGACACAGGGGCGGTGCAAACCAG TGAACACCTTTGTGCACGAGCCCCTGGTAGATGTCCAGAATGTCTGTTTCCAGGAAAAGG TCACCTGCAAGAACGGGCAGGGCAACTGCTACAAGAGCAACTCCAGCATGCACATCACAG ACTGCCGCCTGACAAACGGCTCCAGGTACCCCAACTGTGCATACCGGACCAGCCCGAAGG AGAGACACATCATTGTGGCCTGTGAAGGGAGCCCATATGTGCCAGTCCACTTTGATGCTT CTGTGGAGGACTCTACCTAAGGTCAGAGCAGCGAGATACCCCACCTCCCTCAACCTCATC CTCTCCACAGCTGCCTCTTCCCTCTTCCTTCCCTGCTGTGAAAGAAGTAACTACAGTTAG GGCTCCTATTCAACACACACATGCTTCCCTTTCCTGAGTCCCATCCCTGCGTGATTTTGG GGGTGAAGAGTGGGTTGTGAGGTGGGCCCCATGTTAACCCCTCCACTCTTTCTTTCAATA AAACGCAGTTGCAAACACCTGA OMIM ID 180440