| Entrez gene ID | | 6009 |
| Official gene symbol | | RHEB |
| Full name | | Ras homolog enriched in brain |
| Aliases | | ,MGC111559,RHEB2, |
| Gene summary | | This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq] |
| Location | | Chromosome: 7 Locus: 7q36 |
| Gene position | | 151217010 - 151163098 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 53913 bp |
| Gene sequence |
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| OMIM ID | | 601293 |
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