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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RGS4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5999 Official gene symbol RGS4 Full name regulator of G-protein signaling 4 Aliases ,DKFZp761F1924,MGC2124,MGC60244,RGP4,SCZD9, Gene summary Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] Location Chromosome: 1   Locus: 1q23.3 Gene position 163038396 - 163046592  Map Viewer Gene orientation plus Gene size 8197 bp Gene sequence >RGS4:14527038..14535234:Length=8197 TACTCCCTCCTTTGGTCCTCGAGCTGCCGGTTTAGACTTTTTACAGGACGCAGGCATGTG AAGGAGAAACTGTCAGTGCTAGGCTGAATTCTGTTGTTACCAAGATTTCTAGAAAAGTAT TCCTCAGTCAGGTTGATTACAGATATAGCAAATCTATTTTTCCTAGGGTAGTTTCTGTAT GCTGCCGGGCTTATAACTGTCTGTCATCCAGCTATTTCTCTCCACCTTCTTGTTTGCATA ACAACCAAGGCAACTTCCGCAAATCACTGCGTGGAGACGATGATCCTGCCAGCTCCCTTT TGGAAATCGTGAGGATCAGATCTTGGACCATGTATAATATGATGCTTCTAATCCAAAAGA GGAAAGGCATTGGGAGTCAGCTCCTAAGTAAGCTCCAGAATTCCTGCTGGTACTTTTCCT TCCAGGAAGCAACTTCCTTGATATTTTTTTTTTACAGGCATATGAATAAAAACTATATTT TGCAGCATTGTACACTTTTTTTCCTTTTCTAGAAATTCTAAACCTCTGACATTGGTGGAG ACATTGAGTACATTTTTTCCCATATCCCTACTTTTCAGAAGGATTTTCTCTGCTCGTTCA CTTAACATTGCTGATGCGTCAGTCTTTTCTTCCTCATCTCTTTCAGGGGCTGGAGAGGCA GAGGGAGACAGAGGAGCTGGTACTGCAGAGCGGTCGTCTGATTGGCTGGACGGTCGTAGC TGGGCTATAAAAGAGACCCCTACAGGCTTAGCAGGAAGACGCTCAGAGGATTCTGACAAT ATCTTTACCGGAGAAGAGGCAAAGTACGCTCAAAGCCGAAGCCACAGCTCCTCCTGCCGC ATTTCTTTCCTGCTTGCGAATTCCAAGCTGTTAAATAAGATGTGCAAAGGGCTTGCAGGT CTGCCGGCTTCTTGCTTGAGGAGGTAAGATTGCTTTCAGCCATTAACCATATTAAACTTT TGGCTAGACTTTCTCAGTTATTTACATGTTGTACTTACTAACCTAGTTCTGTGCAATTAG AAACAGTGTGGTCAGGAGAGCACGACTTTCTAACTTTCCTCCAAGACTAGCTAGATATTG TGACTTAAGACATGTGCTCCCCAAATTTCAGCCCTTATGTGTTGTTTTGTGTGACCTCAG TTTTGAGAACTGTTCTATTCTTTAAGCCAGGTCTAAGAAAGCTAGTTTTAATTAAGAAGC GAGATGAGGTTTGAGGCTATGTACAGTGATCTGTAATATCTCCATCTGTGATTACTACTG CTATTTGAGCATCCCTGGAGTACATAGAAGCCTGGCTCTGGGCTTTCTGATTGTATGCTA CAACTTGTTTCAGGAAAGGTACCCCAGAATGAGGTTTGGCTCCATCATCAGAAAGGCACT ATGCTTTCCGTGTGGTGGTGCAGTAACTTTCACTCTCTATGTTCTTATAAGCAAATGTTA CAATGAGATATGAGTTTTAAAGCCAGATCTTCCTTATCTCTCTGCCCCATCTCTAGTTCT TGAAGTGTCTCATATGAGTTTGGTTGAGAAATATTGATCATTACAAATCAGTTAATAGTT TTGTAGAAGATCTCATCTTAAAGACATTGTTTTGTTAATATACTCCCTTGATTTTTTTAA AAGACCTTACAGACATACAGCTATTCATTTGTTTTTGGTTTGTTCAAAAAAGGTATAAAG AAATGCATTCAGAGAAAGATCATATATTAGCCAGTTGAAAATTAAACACAAAATGAGTGC ATATTACATTACTTAATCTTGCAGTCAAAGGTAAAAAGTCAACCTAAAGGTATACTACCT GCTTTCTTATCGCACTGCAAATAGAAATTACCACAAATTTTATTTTGGAAATAATCTCAG AAAACATAATTTTTTATGTACTATTAAAACATTTACTTTCCAAATATTCTGTCATTCAGG AGTATGGAAGTATCGATGGCTTCTTTAAAATGAAGCAGGAGGGTCTGGCAGAGAGTATCT ATGAAATAAGTTCCTCTGACCTTCACGCTTAATTTTCTGAATGGAGTGGAGCAAATTACT TCAAGCTTCACTTAACTTGCATATGAAATGAACCGTACAAAAATACAAGAGTGTCAGGAG AAAGTTATGCTCTGGTAAATATTTTGCAAAACAGATAAAAGATAATACTAGAGCTCTGTC CTCAAAGAGTTAAGCAGCTAATCTAAGGAGGTAAACTCTATGTCAGCAGGATGAACTGCT CTTCCCTTTCCTCCTCAATAAATTGCAAATCATCTAGTCCAACATCTTTACCACCAGTGC CTGAGGCTCCAGAGGAGCCATTGCCTTCTCAAGGTCACATAGGTGGTGGGTGAGTTAGGA CCAAATCTAGAATTCCTGACTCCAGTAACTTCTGAAGTCATTTTGTTTTTTATTTTTATG GTTTTATTATAAGAATACTTGCTAAGCACACTTACCCCCTGCATTGATTAATAACTCTAG GATCTCAGGTGGATCCAGCACATAGAAATATGAATTCGTTTCTATTTGGACTTCATGATA TATTTACATTATCACCTTGGAATCACCCTAACATTCAGGATTGTATCTTGTTATAATCAA AAAGGATGTTGCATCCCCTGAACAGTCATCAGTCAGGGAAGCAGAGGAGGGAAAGTAATC TTGCGAGGAAGAGAAAATACTATTTAAGGGACAGTCAGAGAACATAATGGAATTCAAACT TTCTGGGAAAACCTACATACATAAATGTATTAGTGGCCATCCTAAATGTCTTTATATCTT TGAGGCTTTATTTTCCCTACTCCAAATAGACACATTTAGTTATTCATTTCTTTTAAAATG GTATTTCTCTTTTTAAACTATTTCTTGACTTTTTTAATAAAAAGAGATGCAAGCAAGAGG ATATTTAATAAAAAGTAAGAGAGTTGAGCTTAAGGCTTATTAAAAGACCCCCTTTTTCTA GTTAGTCAGGAGCTCTAATGTGCCCTGGCTACCTATTAAATGGTGGCAATAAACTGGAAG CTCAGTGATGACTCTAGCCTGCTTCTCCTAATAGCTGTTAAGCCTCAAATGCCCTTTAGA GTGTGTATGTCCTTTAAAGTAGCTATTAAGAAGGAAAGCAGCAGCAGCAGATATTGTCTA GAAAGAAGCCCCAAGAAGCTGAGGTTTCAGCTTGGGCATTTGTTTTCGCCATCCCATGCT CCATTTCCCTCTGCTGGAACTGTGCACCTCAGTGTATTCTCCCTCTATACCTCACAGCAG GAACTGCTTGCCCCCCCCCCCCCCCCCCAACATACATGGCTGGAACTGAATAGACTTTTA CTTTCCCGAGGTGCTTCTACAGTTCCCTCTGCCAGCAGGGGAACAGATGGAAATAGCAAT CACCTGCCAGAAGGTGGCGTGCAGCAAGGATGTGCATCTTTTGCCGCTACTGCTTTCTGA TTCCTAAAAATTACTCAGAGATCACTCATGTGTTCAGTGATTCAGGTTCTGTTGAAGATA CCAAAGATATTCGGTTGGTCAAAATGACGGGCATATAAAGGCTTCTCAGGTTTCTGAGGT AAACTGAAGGGTCAGAATTCCAGTTGTGGATGAAGGAAATGGTGTTATGACTGCCTCAAG GTTTTGTAGCAAGTCATAGGGAACCAAGAGGAATCTTGTTTTCCTCAGAGGTCATGCCAA CTCCAACTCCCGTTCCCTAAACTGTCTCTGAGCCATAGACTAGTAATGGACTCTTCAAGC TCTACCATTAGGTATCTTTTAAAGAAAGCTGGTTATTACTATTTATTCATTTTTTTCTCT TCTGTGCAGTGCAAAAGATATGAAACATCGGCTAGGTTTCCTGCTGCAAAAATCTGATTC CTGTGAACACAATTCTTCCCACAACAAGAAGGACAAAGTGGTTATTTGCCAGAGGTAAGA GAAAAGGCCTTGGTGAAGATGTACTTAGTATTAACTATCTGATGATGGGGATGTTCTGTG AGAAGGAACTTGTGCTCCTAGTTAAGCCAGATTTGGATCAAGATAGCCTCCATTTTCATG GAGATCATAACTACATTTGAAATTTCTATACATTTAGTGAAAAACTGCCCTCATCAATAA CATATTTTGTCATAACGATGGAAAATAAAATCTTTGCCTTCATTCAGGATCTTAGATTTC TTGCCCCAATTTTTTTACCATGGCATTCCAATTATTCTGTTTCTCTCTATTTTTTCTAGA GTGAGCCAAGAGGAAGTCAAGAAATGGGCTGAATCACTGGAAAACCTGATTAGTCATGAA TGTAAGTCTGACAGCAACCTGGGATGAGGTACTCTGGATAAGACAAGTTATATTATGCTG GTCTAATAGAAACTGCAGCAAGGCCTGGCTTCTTTCTGATGTTCAGACTCAGGAGACTCT TTAGGTCTTAAATTCAGTCTGTTTAAAATTTTAATATGCCCTAGAGCTTTGTGATATACA ATGAAAAGTTTATGCAGGAACCATGTGGAAAACCATCTCTCTCATCACAAGGAAAAACGG AAGAGAGAAAAAAAATGATAAATATCAATACCTTCTTGCAAAATCAATCTCAGTTTCTCT TTCCCAAATTGACCTTGGTAATTGATAGCTGCATAGGCATTTCAGAAGCAAAATACTTCC TTGAAAGAGGCTTCCAACTTGAGTAAGAATCATTAGGTAGAACTGGGAACCACTGGATAT CAAACACAGATTAGGGTTACCTGACTCCAGGTGACTTGAAAAAAGCAGGGGAAAAAGGGA TTGCTTGAATCCATGCTTTATCCCCCAAGTACCTCAGCTTTATGTGAAATAGCATATCCA AGAGGCCAACCAGTGTGATGACAACTGTGGTCCTTTCTCCTGTATCATAGGTGGGCTGGC AGCTTTCAAAGCTTTCTTGAAGTCTGAATATAGTGAGGAGAATATTGACTTCTGGATCAG CTGTGAAGAGTACAAGAAAATCAAATCACCATCTAAACTAAGTCCCAAGGCCAAAAAGAT CTATAATGAATTCATCTCAGTCCAGGCAACCAAAGAGGTAGGTTTTTTATGGATACATAA AAATTGTACGTATTTATGGAGTATGTGTGATATTTTGATACATGCATACAATGTGATAAC AATCAAATCAGGGCAATTGCTATATACATATCTCAAACATTTATTATTTCTACGTGTTGA GAACATTCCAAATCTCCTCTTCTAGCTATCTTAAAATATACAATAAACTATTGATAACTA TATCACCCTAATGTGCTATCAAACACTAGAACCTATTCCCTCTACCCAACTTTCTATCTA TTCCTTCTACCCATTAGCCAACCTGACCAAAAAGGTAAGCTTTTATGGCAGAGAACTCTC TGGATCTTAGTGAAGGTTCCTAGAATAGTGGAGCTGACTATCATAATCTTGACAACCCCA AATAAATCAGTTTTTTAAAAAATCTCTTTTATCCATGTGGCTTACCATAACCTCCCTGCA TGAATTTTTCTGATGAATCTCCCCAATTTGTTAGACAGAACAGAAGATCTTGCCCTGCTC TCTCTAAAGCAGAAAGGTTCATTCTGAACCTTTCATACTCTCTCACATGTGCCAAGGAGG ACCCCAATGTCACTTTTGTTTTTTGCTTCTGAAATACAGAGGGTGCACTGCCACTTACAA GTCACTACAAAGCATACAGGCTTGCATCCTCAACAGGGATATAGGTCTAATGAAGCCTTG GCCTTTGCCCCTCAGGTGAACCTGGATTCTTGCACCAGGGAAGAGACAAGCCGGAACATG CTAGAGCCTACAATAACCTGCTTTGATGAGGCCCAGAAGAAGATTTTCAACCTGATGGAG AAGGATTCCTACCGCCGCTTCCTCAAGTCTCGATTCTATCTTGATTTGGTCAACCCGTCC AGCTGTGGGGCAGAAAAGCAGAAAGGAGCCAAGAGTTCAGCAGACTGTGCTTCCCTGGTC CCTCAGTGTGCCTAATTCTCACCTGAAGGCAGAGGGATGAAATGCCAAGACTCTATGCTC TGGAAAACCTGAGGCCAAATATTGATCTGTATTAAGCTCCAGTGCTTTATCCACATTGTA GCCTAATATTCATGCTGCCTGCCATGTGTGAGTCACTTCTACGCATAAACTAGATATAGC TTTTGGTGTTTGAGTGTTCATCAGGGTGGGACCCCATTCCAGTCCAATTTTCCTAAGTTT CTTTGAGGGTTCCATGGGAGCAAATATCTAAATAATGGCCTGGTAGGTCTGGATTTTCAA AGATTGTTGGCAGTTTCCTCCTCCCAACAGTTTTACCTCGGGATGGTTGGTTAGTGCATG TCACATGACATCCACATGCACATGTATTCTGTTGGCCAGCACGTTCTCCAGACTCTAGAT GTTTAGATGAGGTTGAGCTATGATATGTGCTTGTGTGTATGTCTATGTGTATATATTATA TATACATTAGACACACATATACATTATTTCTGTATATAGATGTCTGTGTATACATATGTA TGTGTGAGTGTATGTATACACACACACACACACACACACACACACTTTTGCAAGAGTGAT GGGAAAGACCCTAGGTGCTCATAACTAGAGTATGTGTATGTACTTACATGGGTGTTTTGA TCTCTGTTCTTTCATACTACATTTGAACAGGGCAAAATGAACTAACTGCCATGTAGGCTA AGAAAGAAATGCTAACCTGTGGAAAGTTGGTTTTGTAAAATTCCATGGATCTTGCTGGAG AAGCATCCAAGGAACTTCATGCTTGATTTGACCACTGACAGCCTCCACCTTGAGCACTAT TCTAAGGAGCAAATACCTTAGCTCCCTTGAGCTGGTTTTCTCTGATGGCACTTTTGAGCT CCTAAGCTGCCAGCCTTCCCTTCTTTTCCTGGGTGCTCAGGGCATGCTTATTAGCAGCTG GGTTGGTATGGAGTTGGCAGACAGGATGTTCAACTTAATGAAGAAATACAGCTAAGGCCT TGCCAGCAACACCTGCCGTAAGTTACTGGCTGAGTGAGGGCATAGAAGTTAAAGGTTACT GTTTTTATCCTCTATCCTTTTTTCCTTTCCTGATCAAGGTGCTCTTCTCATTTTTTCCTG AGAACCTTAGCCATCAGATGAGGCTCCTTAGTTTATTGTGGTTGGTTGTTTTTTCTTTAT AATGGCTCTGGGCTATATGCCTATATTTATAAACCAGCAGCAGGGGAAAGATTATATTTT ATAAGAGGGAACAAATTTTCACAATTTGAAAAGCCCACATAAGTTTTCTCTTTTAAGGTA GAATCTTGTTAATTTCATTCCAAACATCGGGGCTAACAGAGACTGGAGGCATTTCTTTTT AGGCTCTGAGACTAAATGAGAGGAAAAGAAAAGAAAAAAAAAATGATTGTCTAACCAATT GTGAGAATTACTGTTTGAAACTTTTCAAGGCACATTGAAATACTTGAAAACTTCTCATTT ATGTTATTTATGATGTTATTTTGTACGTGTTATTATTATTATATTGTTTTATAAATGGAG GTACAGGATATCACCTGAATTATTAATGAATGCCCAGGAAGTAATTTTCTTCTCATTCTT CTAAAACTACTGCCTTTCAAAGTGCACACACACGCGTCCACATACACTGCATTCGTTGCT CCAGTATAAATTACATGCATGAGCACCTTTCTGGCTTTTAAGCCAATATAATGGGCTGCA AAATGAAGACACCAGAGTGTATGCATACAAATCTCACTGTATTAAAGATGCAGGTTTTCT AATTGTACCCTTCTTGTCTCTCTGGCAATCTTGCCCTTAATATCCCTGGAGTTCCTCATC AGTGTCATTTTCTGTTATACACAGTTCCACAATTTTGTCTCTAGTTGACTTCAAATGTGT AACTTTATTGGTCTTGCCCTATTATAATTGTCATGACTTTCAGATTGTATCTGAACTCAC AGACTGCTGTCTTACTAATAGGTCTGGAAGGTCACGCTGAATGAGAAGTAAATTATTTTA TGTAATACATTTTTGAGTGTGTTTTTCAGTTGTATTTCCCTGTTATTTCATCACTATTTC CAATGGTGAGCTTGCCTGCTCATGCTCCCTGGACAGAATACTCCTTCCTTTTGCATGCCT GTTTCTATCATGTGCTTGATAGGCCTCAAAGCTAATGCTTCCAGTGAAACACACGCATCT TAATAATAAGGGTAAATAAACGCTCCATATGAAACTA OMIM ID 602516