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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RFC4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5984
Official gene symbolRFC4
Full namereplication factor C (activator 1) 4, 37kDa
Aliases,A1,MGC27291,RFC37,
Gene summaryThe elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q27
Gene position186524484 - 186507681  Map Viewer
Gene orientationminus
Gene size16804 bp
Gene sequence
OMIM ID102577