| Entrez gene ID | | 59272 |
| Official gene symbol | | ACE2 |
| Full name | | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Aliases | | ,ACEH,DKFZp434A014, |
| Gene summary | | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq] |
| Location | | Chromosome: X Locus: Xp22 |
| Gene position | | 15620192 - 15579156 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 41037 bp |
| Gene sequence |
| |
| OMIM ID | | 300335 |
|