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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PVR (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5817 Official gene symbol PVR Full name poliovirus receptor Aliases ,CD155,FLJ25946,HVED,NECL5,Necl-5,PVS,TAGE4, Gene summary The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.2 Gene position 45147098 - 45169429  Map Viewer Gene orientation plus Gene size 22332 bp Gene sequence >PVR:17415316..17437647:Length=22332 AGCGGGACTGAGCGCCGGGAGAGACCTGCGCAGGCGCAGGCGCGCGGGAAGGGCCAGCCT GGGTGGCCCACCCCGCGCCTGGCGGGACTGGCCGCCAACTCCCCTCCGCTCCAGTCACTT GTCTGGAGCTTGAAGAAGTGGGTATTCCCCTTCCCACCCCAGGCACTGGAGGAGCGGCCC CCCGGGGATTCCAGGACCTGAGCTCCGGGAGCTGGACTCGCAGCGACCGCGGCAGAGCGA GCGGGCGCCGGGAAGCGAGGAGACGCCCGCGGGAGGCCCAGCTGCTCGGAGCAACTGGCA TGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCT GGCCACCCCCAGGAACCGGTGAGTGACCCCCGCGCAGTCCGGTGGCCCCTGTCTGGCTCC CGCTCCGCATCCAGGCCGGGTACTTGCCCCCTTGGGTTCCCGAAGATGACGGCCCCGCCG CGGCGCCACCCACCCCCCATCTCTGCCCCGGGGTTGGAAGGAACACGGTGCGAGGGTGCG AGGGCAGGACCCTCCTCTTGGCCACCCGGAGAGCGGTCGGAGTTGGGTACAGAAATTCCT CGAAATTGGCAGCAACACGGGTCGGGCACAAGACCCTCCTCTGGGCCCCTCGGAAAGGGG ATGGAGTTGGGTGAGGAAATTTCCCAAAAAGGCAAGTGAATCCCGGAAAATCAGCAGATG GTGACGCATGCCGGATTACCTTACCCAGGTTCCTGCTCAGCATACCCAGGCCATAACCCA GCAGCGTGCTGGCAGGCTGGGTCTGGACGGAGGGGATGGTTGATGTTGGGGAGGAGGACA GTGGGTGACACTTGACACCATTACCCCTCTGACCCCCAATGTCTGACTCCAGGGGCCTGG CCATTCATTCATTCTTTCATTCTTTTTTTTTTTTTTTTTGAGACAGTCTCACTCCATTCA CCCAGGCTGGAGTGCAGTGTCCTGCTCTCGGCTCACTGCAGCCTCCTCCTCCCGAGTTCA AGCGATTCTCCTGCTTCAGCCTCCCGAGTAGCTCGGATTACAGACATGTGCCACTATGCC TGGCTAATATTTTTGTATTTTTAGTAGATACAGGATTTCACCATGTTGGCCAGGCTGGTC TCAAACTCCTGATAAATATATATATTATATATTATTATTATATATTACATATTATAGTAA TATATAATAAAAATATATAATATATATTATAGTAATATATAATATATAATAAAATATATA ATATATATTATATATTATAGTAATATATAATATATAATAAAATATATAATATATATTATA GTAATATATAATATATTATAATATATTATATATATTATTATAATATATAATATGTATATT ATATATTATATATATTATTATAATATATAATATGTATTATGTATTATATAATTGATAATA TATAATAATATATTTCTTAATAAATATATATTAAATATATTATATATTTATAACATATAT TATTTATATAATAAATAATATATATTTTATTATACATTTAAAGAGTAAATAGATAACATA TTTTATTATTTATTTATATATTTTGTGTATATATATATATATATATATATATATATATAG TGCGTGTGTGCGTGTATGTGTGTGTGTGTATGAGAGAGACAAGGTCTTGCTTTGTTGCCC AGGCTGGAGTGCAGTGGTACAATCCCGGCTCATTGCAAACTCGACTTCCCAGGCTCAAGC GATCCTCTCACTGTGGCTTCTGGAGTAGCTGGGATTATAGGTGCTCACCTGGCTAATTTT TTTTGTATTTTTGGTAGAGACAGGGTTTCGCTATGCTGCCCAGGCTGGTTGCAGCCAAGC ACAGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGTGGTGGGAGGATCACTTGA GCTTAGGAATTCAAAACCCGCCTGGGCAATATGGCAAGACCCCATCTCTACAAAAATAAT TAACTAAATAAAAATTTAAAAATAAAAAAGAATGCATAGGACCATGTTTATTAGTGTCAA TAAGCGCTGTCACATTTTGAGGACCTACTATGTGCTAGGGCCCTTAGCAGAAAGATTTTT ATATAGGACCTGGGGGATTAGAGGTCAGTCTCTGACCGCCCAAGTTCAAATCCCACCTCT GCCACTAAACCTCTGTATGACTTGGAGGACACTATACTCTGTGTCAGTTTCCCTGTCTGT AAAATGATGTTAACAGTAGTGCTTGCCTCAGGGGGGCTATTTGAGGATTAAATGCCAAGA TATATGTGAAGCACCCAGAATAGCCCCTGATCTGTGTCAGCACCCTGTGAGTGTCCACTG TTCTAAGTCTCATTTTACAAACTAGGAAAAAGAATCAGAGAGGTTAAGTAACCGGCCTGA AGCTCCACAGCAGAAAACTGAAGGGACCCAAAACTCCTGGGCTATAATTGCCTTCCTCTC GTGCCTCAATCCCCCACATTCTTCCAACCAGGACCCACCCAGAGTAATAATGCAGCGTTT CATGGATTTGAAGACCCAAGATTTCTCCCCGTTTTCTACATTGGGGTTATTCTAACCCCT AATGGCAAGTTGTGCTATAAATGACAACAGTCATGGTATGTGAAACCTACGACACTGGTG CGATGAAAAAGTTCTGGGCCAGGTGCGGTGGCTCATACCTGTAATCCCAGCACTTTGGGA GGCCGTAGTGGGAGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTG AAACCCCATCTCTGCTAAAAACAAAAATAACAAAAAATTAGCCAGGTGTGGTGGTGGGAG CCTGTCATCCCAGCTACGCGGAAAGCTGAGGCAGGAGAACCGCTTGAACCCCAGAGGCAG AGCTTGCAGTGAGCAAAGATCGCGCCACTGCACTCCCCCTGGGCGACAGAGAGAGACTCC GTCTCAAAAAAAAAAGAGAAGAAAAGAAAAAGTTCTGGCGCTATATAGTAGTAATGTTTG TATAATATCGTGAAATGTACTATAGTGCCACTGAACTGTATTTTTTAAATGACTTAAATG GTAAATTTAGTTTTTTAACCACAATATTTACCACAATTTTTTAAATCAGTGATGTTGAGA TTTCAGGGAAATACGGTAATAATAGAAGAAATACGGTAATAAATAGCCAAAGTGAAGGAG CACGGCCAAGTTGCAGACCATCCCAGACGCCCTTACCCTCCTCGCCTGCCATGGCCCCAA CTAGTGCCCCAGTTCCCCCTCCCCCCACACCCCACGGTCCACCGGGGATCCAGGGCCCCA GCGTGCAAGTCGCGCCAGGTGCCCGGGCTCCTGGAGCCCCTCCCTATCTAGTCCAAGAAC GCCCCGGGTCTGACACCTTCTCTTCGGTTCTCCGCAGGGGACGTCGTCGTGCAGGCGCCC ACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCC AACATGGAGGTGACGCATGTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGC ATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAACGGCTGGAATTC GTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGC GTAGAGGATGAAGGCAACTACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGC GTGGATATCTGGCTCCGAGTGCTTGGTGAGCAGGGGGTTTTGGGGAGGCTGAATGAAAGG CAGAGACTTGGTGGGAGGATCAGGGAAGTTGGCAAAGAGCGGGGAGGCCTGGGAGGGAGG GAGATTCCCTCCACAGCAGATCCCCTGGGGACAAAAGGAGGGGGCAGCGCAATGATGTGG GGTGGGGTGGGGGGAGGTGAGTGGGGGGAGGGGCTGCAGGGCAGGAAGAAAGCAGAGATC TCAGGGAGTAAGGACCCCCAAGCCTGGGATCAGAAAGCCCTGAGGGAGGAGGAGGGGTAT ATTGGAAAGGGAGCTGGGAGGGGACTGGGAAGGAAGGGAGGAGGCCTGGGTGGCCTCTTC TGGGTCCCTCCTTTCCTCATCTGTAAAAGGGTTGGTGACAACAGCATCACCCTTGGAAAG CTGTCCTGAGTGTCATCACTGCCTAGGAAAGAGTCTGTCTGCCCCCTTGGACTGTGTACC CATGAGGGCAGAACCGGGGCTATTTTGATCACTGCTGGGCCCCAGCACTTTCCACCAAAC AATATTTATTGAGCACTTATTATGTGCCATTCTAAGAGCTTTACCTGCATATTCTAATTG CCTGTGATTCCATCATTATCACCTGTTGACAGACAAGGAAACTGAGGCACAGACTTGCCC AAGACCAAAGCTGCAGCCTTAGGGCAGCGGCGCTTCACCGCTGGCCCATGTGAGCCCCTT AGAGCTGTCGGTTACTGTTACTTTATCTGGTGAAGAAGGAGAAAGTTGAAACAGACAGAC AGGAAAGCAAGGATCCTGATACCCAAAAGAGGAGGGGATCATGCTTTCATTTTCATGAGC TCCATGAAGCCTTCCTCTTGGAACTTGAGCAAGAAGTCTCTGTGCCTCAGTTTCCTCATC TGTGGGATAGGGATCACCATGAGGATTCAAAAAAACTGACCCTTTTTTTTTTTTTGAGAT AGTTTAGTTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTGATCATAGTAGGTCCTCACTGC AGCCTGGAACTCCTGGGCTCAAGGGATGTTCCTACCCTCCCTGTAGCTGGAATTACAGGA ATGTGCCACCATGCCCAACTTGTTTTCTGTTTTGTTTTGTTTTGTTTTGTTTTCTTTTCT TTTTAAGCTTATGTGCCAAGAACTATTCCAAGCCTGTGCATGAGAAACTCATGAAATGTC AAGGGCTTGGAACTGTGCCTAGCACACAACACCCAACCAAAGGCAGCTGTTGTCACTCCA GCAAGCCTGGGATTCTGGGTATCATGGTTTAGGATGAGGGTAAAACAGAAACAGTGAGTC AAGTTAAGGAGAAATCTTCGGTAAATAATATAGGTAATGATGGGGAAGGAAGTTCCAGGT TTGGGAATCACCAGGATGATGATTAAGAGATGGTCAAGGTGGTTTTGGAGTCAGACAGAC TTTATGTGAAAGCCCAGCTCTGCTGCTTACAGCTGTGTGACCATGGGCAAGTCACTTCCC TTCTCAACTTCAGGGCTCAGGCTTCCTCTCCTCCACTGAGCCCCAGACCAGGATAACCCC CTTTGGGTTTCCCCTTTCCAGCCCTGCCCTCTCCGAGTCATCACTGCCTAGGAAAGAGTC CGTCTGCCCCCTTGGACTGTGTACCCATGAGGGCAGAACCAGGGCTATTTTGGTCACTGC TGGGCTCCAGCACTTTCCACCAAACAATATTTATTGAGCGCTTATTATATACCATTCTAA GAGCTTTACCTGCATATTCTCATTGCCTGTGATCCCATCACTATCCCCTGTCAACAGACA AGGAAACTGAGGCACAGACTTGCCCAAGACCACACAGCTGCTCAGGGACACAGCTGGGAT TTAAACCATGCCATTCTGTATCTTTTTTTTTTTTTTTTTTTTGAGGCAGAATCTCACTCT GTCGCCCAGGCTGGAGAGCAGTGACACAATCTCAGCTCACTGCAACCTCCGCCTCCCGAG TTCAAGCAATTCTCTGGTCTCAGCCTCCCAAGTAACTGGGATTACTGGCGTGTGCCACCA TACCCTGGCTAATTTTTAATAGAGACAGTTTCTCCATGTTGGCCAGGCTGGTCTCGAACT CCTGACCCCAAGTGATCCACCCACCTCAGCCCCCCAAAGTTCTGGGATTATAGGCGTGAG CCACCCCGCCCAGCAACCATGCCATCCTGTACCCTTAATGAATGCCCCCTTCTGCCACGG AGGGGTTCATTGAATGACTTGTTGCTTTTGTTCCTCTTCCCAGCCAAGCCCCAGAACACA GCTGAGGTTCAGAAGGTCCAGCTCACTGGAGAGCCAGTGCCCATGGCCCGCTGCGTCTCC ACAGGGGGTCGCCCGCCAGCCCAAATCACCTGGCACTCAGACCTGGGCGGGATGCCCAAT ACGAGCCAGGTGCCAGGGTTCCTGTCTGGCACAGTCACTGTCACCAGCCTCTGGATATTG GTGCCCTCAAGCCAGGTGGACGGCAAGAATGTGACCTGCAAGGTGGAGCACGAGAGCTTT GAGAAGCCTCAGCTGCTGACTGTGAACCTCACCGTGTACTGTGAGTGTGCCCAAGTCAGC GATGGCAAGAACCCCTGCCGGGCTGCCCCCACCACTGTCTACACTGACTCCCCAAGGCAC TGTAGGCATTGCTTCCATCATCTGCACCGGCTCCCCTGACTCCTGTCTACACGACCCACC CCCATTGTCTGCACCAGCTCCCCTGGGCCGTAAACAACACTGTCCCTATTGTCTACACCA GTTTACTTGGGCCATAGTCAATGCTGGTACCCAGACTGTCTGCCCTGGCTCCTCTAGCGG CTGTCTGCACGGATACCTGACACTCTGTTGACTCCCTTGAGCACAGTCTACACTGCCCCT AAACTGCCTACACCCATTTCCCCAGGCAAGTATCCACAATGACCCTCCCCACATTGCTAC ACTGGTTCTTCTGGCCACGATCAACACTGCCTCCCTTATTGTCTACACCCACTCCCTTGT CCTTTTCTTTCTTTCCTTTTTTTTTTTTTTTTTTTGAAATAGAGTCTCACTCTGTTACCC AGGCTGCAGTACAGTGGCATGTTCTCGGCTCACTGTAACCTCTGCCTCCCAAATTCAGGT GGTTCTCCTACCTCAGCCTCCCAAATAGCTGGGATTAAAGGTGCACACCACCACACCTGG CTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCAGGCTGGTTTCGAA CTCCTGACCTCAGGTGATCGGCCTGCCTCAGCCTCCCAAAGTATGCTGGAATTATAGGCA TGAGCCACTGTGCCCGGCTTTTTGTTTTGTTTTGTTTTTCCTTTGGACAGGGTCTCGCTC TGTCACCCAGGCTGGAGTGTAGGGGCATGATCATGGTTCCTACAGCCTCACCCTTCCAGG CTCAAGCAATCCTTCTCCCTCAGCCTCCCAAGTAACTGGGACTACAGGTGCAGCCACCAT GCCCGGCTAATTTTACAGTTTTTTTCTAGAGAGAGTTTTGCTGTGTTGCCCAGGCTGGTC TCAAACTCCTAGGCTTAAGTGATCCTCCCGCCTCAGTCTCCCGAAGTGCTGAGATTACAG GCGTGAGCCACTGCACCTGGCCCCTTGTCCATTTTCTACACTGCCTTACCATTGTCTACA CTGGCTCTCCTGGGCCACAGACAGCACTAACCCCATTGTCTACACCACCTATTTTGGCCA CCAGCTGTGGGGTGTTTTCACTGTCTCCCATAGTGTCTACACTGGCTCCTATGACCACTG TCTATGTAAACACCCCACTTTTTCTACACTGGTTCTCCTAGGCACTCTCTAAAGTGCCCC CTGACACTGTCTACACTGACTCCCTGGAGAACTGTCTGCATTCACCTCCCACATTGTATC GACCAGTTCCCCTGAGCCACGATCAACTGTCTCCGCCGGGTGCTAGTTGCATTGATCTTC TCACATTGTTTGTGCTGGCTCCCCTAAGCAGTGTCTGCAGAGTCCCCCAGTGTAGTCTCC ATGTTCCTCTGCCCAATATTGTCTACACTGGCTCATCTACAGGCTATCCAGTCTCACCCC ACATCACCACACTGGCCTCCTTGTGTTCTGTCTGCACAGCCCCCTGACAGCATCTGTCCT GATTCTCCTGCACAGCGTTACCTCCACCAGCTCCCTCATGGCATCATCGACATTGACACC CACACATTTATCTCCACTGACAGCCCCAGGACTCTCTAACCAGTGCTGTCTAACAGAAAT AGCATGCAAGCTGCATATAGGATTTTAAATTCTCCAGCGGCCACCCCATTAAAAAATTAA AAGAAAGAGGCCAGGCACGGTGTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCA GGTGGATCACCTGAGGTCAGGCATTCAAGACCAGCCTGATCAATGTGGTGAAACTCTGTC TTCACTAAAAAATACAAAAATTAGCCAGGCACGGTGGCGGGTGCCTGTAATCCCAGCTAC TCGGGAGACTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGATTGCAATGAGCGAG ATTACGCCATTGCACTCCAGCCTGGGCAGCAGAGCAAAACTCCATCTCAAAAACAAGAAA AGAAAGAGATGAAATTTATTTGTTTATTTATTTATCTATTTATTTATTTGAGACGGGGTC TTACTCTGTCACCCAGACTGGAGTGCAGTGGCACAGCTCCCTGCAGCCTCAACCTCCTGG GCTTAAGTGATCCTCCCACCTCAGCCTCAGTCTCCTGAGTAGCTGGGACTACAGGCGTGT GACACCATGCCTAGCTAATTTTTGTTTTTGTTTTTGTTTTTGTTTTTTTGTTTTGTGATG AAGTCTTGCTCTGTCACCCAGGCTAGAGTGCAGTGGCACGATCTCAACTCACTGCAGCCT CCGCCTCTCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAAG CCCTGGCCACAGTGCCCAGCTAATTTTTGTATTTGTGGTAGAGACGGGATTTCACCATGT TGGCCAGGCTGGTCTCAAACTCCTGACCTCGTGATCCACCCACCTTGGCCTCCCAAATTG CTGGGATTACAGACGTGAGCCACCGCACCCGGCCTATTTTTATTTTTTCTGGAGACAGGA TCTCCCTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCCTCCTGCCTCA ACCTCCCAAGGTACTGGGATTACAGGCATGAGCCACTGTGCCTGGCCAAAATTAATTTTT AATAATTGCCTTTACTTAACCCAATATACCTAAAATATTATTTCAACTTGTAATTGTTTT TTTAAAATTATTCTTGAGATCTTTCCCATTTATTTTGTCCTAGTAAAGCCTTTGAAATCT GGTGTGTATTTCGGCCTGGCTATATTTCGAGTGCTCAGTAGTCACATGTGGCCAGTAGGT GCCATATTGGACAGCACAGATCTAGACTAAGCTCCCACATCATCTACACTGGCTCATCCA AATACTGTCTACACACATACACAGAGCCTGTCTTAATTTCGTCAGCTCCCGGGGACACAC TGTATATGTGGGGGTGATCTCACCCCCACCACCACATTTTCAACACTGGCCCGACAATAT AGCATCTGCTGTAATATTCCAACACCCTGTCTACACTGAACCCATCAGTAATATCCACAC AAGCTCTTCTAGACATCATTCATACTGTTCCTCCCACCATTGTCTATACTGCTTACTCCC CGCCAGGCAATTGGTACACAGATTCCCTCAGGTACTGTCTATACTGGAGTCCCTCAACAC TGTCACTGGGTCTGAGCGAGGAGGAGATCTACACTGACTCCTACCCCTCGCCCCCGAATA AAACCCTGTCCCATTGGCCTGCCCCCAAGGACATTGAAAGGTCTTCGCTGTCAATCACGT ATGGGATGGCTGAGCAGCAGCCTAGAGCAGGGTTATCTGGGACTCTTTCCTGCAGGACTT GTCAGAACCTTGAATACACTGCTGTGTGTTGTGAGTGGTCATTGCCTATGAGTGAGAAAA GGAGGAGGCATTTTCCTGCAGGACACCCAAGACATGCCTGGTCCAGGCTACCCAGGAAAG CTAGTGGAGAAAAGCAGCTCCTCAGAAGCCTTCTCCATGTCCCCACTGACCAAGGACTCC TAGGCTTCTGCTCTCTGTGGCACCCCATCTACCTAGACTCCTCCTAGGCCTCTCCAGCTC CCGCTGTTTTCCAAATATCCCCGGGCCTTTTCCTGCAGTGTCGTGAATCCCGCGTACCCC AGGCCCCCCAAAGCCTCCCAGTCTCTGAACCTCTGTATCCATTTCCTGCAGACCCCCCAG AGGTATCCATCTCTGGCTATGATAACAACTGGTACCTTGGCCAGAATGAGGCCACCCTGA CCTGCGATGCTCGCAGCAACCCAGAGCCCACAGGCTATAATTGGAGCACGTGAGTCCTGG GTCTCAGGGAGGAGGGGCTGGGGGTCTGGATTTCTAGCACTGAGGGAGGAGGGGCTGGGG GCCTGGACTCCTGGGACTGAGGGAGAAGGGGCTGGGGGCGGACCCCTGGGTCTGAGGGAC GAGAGGCTGGGAGCCCGGACTCCTGGGTCTGAGGGAAGAGGGGCTGGGGGTCTGGACCCC TGGGACTGAGAGAGGAGGGGCTGGGCCTGGACCCCTGGGTCTGAGGGAGGAGGGGCTGGG GGGTCTGGACCCCTGGGTCTGAGGGAGGAGAAGCTGGGAGCCTGGACCCCTGGGTCTGAG GCAGGACAGACTGGGGCCTGGACTCCTGGTCTAAGAGAGGAGGGAGATTCAGAAAAGAGA AAAAGAGGAGGTTGACTTCGGGCCCCCAGTGGGGGGCATCTCTGTTTTGACATCTCTGTT TTGCGGTTGAGGCGTTTAGCAGGTGGTTGAATCCTGGCTGGTGGATGCACCTGCTTTTTG GGGTGTGCCTGCTCTGTGCCCGGTACTTCCCCCGAATCCCATGTGACCCCATGCTGTGCA CAGTCAGCAGCTGTTGCCCTGCCCAGGTTAAAGACCAGCCACGAGAGGGCAGAAGCGGCC CTTGAATCAGCGCTCGGCTCCAAAGCTGGTCCTCCGCCTCTTGGCCAAGCTTGTCTAACC TGCAGGCCACATCATTTGTAAACTTTCTTAAAACATTATGAGACTTTTTTTTTGCGAATT TTTTTAGCTCATTAGCTATTGTTAGTGTTAGTGTATTTTATGTATGGCCCAGGACAGTTC TTCTTCTTCCAATGTGGCCCGGGGAAGCCAAAAGATTGGACACCCCCACTCTAGACTGTA ACCACCTCACCGTCACCTTGTGTAACCTACTTGGTTATCTCTGGATGGAGCAAGTACTAT ATATCCCCATTGTCTAGATGAGAAAGTTGAGGCTCACAGCAATAAGATTTCCCCAGATTC ACACTGAGGCTGAGATCAAGAGCAAGGTAAGAAAAAGGCAAAGAGATAATACATAATTTT ATAATACATAATTTTACATAAATTACATAATTTTACTGAACCGCCCTTTTTTTTTAAAGA AGGGGCTCTGTTGCCGAGGCTGGAGTGCAGTGGCGTGATCATAGCTCACTGCAGCCTGGA CCTCCCTGGGCTCAGGTGATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCA CACGCCACCACACTCAGCTAATTTTGTTGTATTTTTTTTGCAGAGACAGGGTTTTGCCAC ATTGCCCAGGCTGGTCTGCAACTCCTGGGCTCAAGCAATCAACCCACCTCAGCCTCCTAA AGTGCTGGGATTACAGGCGTGAGCCACCTCGCCCAGCCTTAGGTCTTTTTCCTTATTACA AAAATAACTTGTGTCCACTGTAGAAATATCAAACAATTTAGTTATGAGCAAAAAGAAGAA AGTAGTGCCTATAGTTCAAGTGTACCCAGCCACCTCCAGAAATACCCAGTGACCCCTTAT TATACATCCTGTCTTTTTTCTCTCTGTTTCTAAACAAAGACTGGAATTATGCTGTACATA TAATTTTGAACCTTTTCGTCTGTCTTGTGAATACCTTTCCATGTCAAAGCACATAGATCC ACAACTCCATTTTCCCCCACGTTGTATTAGGAAGACTGTCAAACATACAGAAAAATCATA GGAATTTTCCAGTGAACACTTAAGATTCCACCACGTGGATTCCCCTGCTAACATTTTACT GTGCTTGCTTTATCACGTTTCTGTGATTCCTTCAGTCCCTCTATTCATCCATCAATCATA TTATGCATTTCAGAGCACCCCCAGCTCTCCTGCTTTTTTTTTTTTTTTTTTTTTTTTTGA GGCAGGGCCTCACTCTGTTGCTCAGGCTGTAGTGCCGTGGCACAATCACAGCTCACTGCA GCCTTGAATTCCTGGGCTCAAGCGATCCTCCAGCTTCAGCCTCCCAGATAGCTGGGACTA CAGGCACACACCACCACGCCTGGCTAACCTGGCCCCTTTTTTAGTGTTGCTGGGATTCCA CCACTTTAAAAAAAAAATTCAAAGAATAGAGACAGGATCTCACTATGTTGCCCAGGCTGG TCTTGAACTCCTGTACTCAAGCAGTCATCTCACCTGGGCCTCCCAAAGGGCAGGGAAGGG ATTCCAACATATGTGGATGTCATCAGTTATTTAACCAGTCCCTAGTAGAGGACACAGATG TCATTTTCCATTTTCAACTCTGCAAATGCCATGGTGGTGTCCATCCCCACTGGTCACTTG TCAGCAGTTGTCCGTGGAAGGAATTGCCGGTCAAAGGTTTTCAACTGGTGTGATGGTGCC TTTACTGTCCTGCCTCAAAGCACCGCAATTCAGGCTCTTGAGCCAGATAGCTGCGTTTGC ATCCCAGCTCTGCGGAGCACCCAAAGCCTGATGCTTCCATCTCCTCCACCTCTGTTCATT AAACCAGTGTTCCTTGACTACTTACTGTGTGCCGGGTGCAATTAACCAACATACGTTGGT CGATAAAACAGACCAAATTTCCTCCCCATATAGAGCTTCCATTCTAGTGGTGAAAGAAAC AAGAAGCAAGATAAAGTGTGTAGTGTGTGTGCAATGGTGATAAATACCATGGAGAAGACA AAGCAGAGAAGGGAATGGGACTGGGCGCCATGACTCATACCTGTAATCCCAGCACTTTGG GAGGCAGAGATGGGAGGATCACTTGAGGCTAGGAGTTCAAGACCAGCCTGGCCAACATGG CGAAACCCCATCTCTACCAAAAAAGATACAAAAATTGGCCGGGTGTGGTGGCATGCACCT GTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAAGATTCCATGCACCCAGGAGGTGGAGG TTGCAGTGAGTCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACGCTGT CTCAAAAAAATAATAATTAAATAAATTAAAGAGAAGGGGATGGGAAGGGTGATCATCACA GTTGAAATAGGGTGGCCAAGTGAGGTGTTACTAAGGTGACATCCCAGCAGAGGCCTGAAG GAGATGAGGGTGAGCTCTGCGGGTGCCTAGGGGGAAAGCATTCCAGCAGAGGGAACAGCA TGGGCAAACCCATTTCTATCCATCAGTCCCTGCATAAGCAAACACCCTGGACACCTAACT GGAGAGTTTGAGGACCAACAAAGAGGCCACTGTGGATGCAGAGGCGGGAGCAAAGGGGAG AGTAATGGAAAACGTGGGCAGAGGTAGCAGGGGCCAGATCACGTGGGGCCTGTGACACCA GAAGACTTCGGTTTAACTCTGAGCCAGGCTAGGCCCCCAGAGGGTACTGAGCTGAGGTAT GGGAACTGACTTAGGGTTCACAGGCGACCTCTGGTGGCCATGTGGGGAACAGACGAGGGG GCGAGGGCAGAAACGGAGCCCAGCGTGGAGGCGGCTGCTGGGGGCCGGGATGCACAGCGC CAGAGCAGGGAGGTACCGTGGAAGCCCTGAGGAGAGGTGGGATTCTGGATGGATCTTAAG GCGGGGCCGACATGATTGGCTAATGGGTTGGGTGTGGGCATGAGAGGAAGGGAAGAGTTG GGGGGCCTCCAGAGTTGCTCTCCGCTTATGCTATAGAGGGCGTGAGGGTTTCTGGGCACG TAGTGCGTGCTCAATCACTGTCACTCCGGACCTGCAGCAGAGGCCACCTCCTCACCTTTC TGTCTCTCCCAGGACCATGGGTCCCCTGCCACCCTTTGCTGTGGCCCAGGGCGCCCAGCT CCTGATCCGTCCTGTGGACAAACCAATCAACACAACTTTAATCTGCAACGTCACCAATGC CCTAGGAGCTCGCCAGGCAGAACTGACCGTCCAGGTCAAAGGTGAGGAACTCCCTGGGTG GGAAGAACAGGGACCAAAGGAAGAGGTCGAGGCAGGGTTCCCTGTCTAATGCTCTCTGGC TCCCATCCTTCTCCTAAGCCTTCTCACAAAAGGACCAGTGGGGCCAGCTTTACTCCCCTG TTAACTCCATACCTATATCACTGGTACCGTTGTTCAGCTGCCTGGATACACTCCCTCCAC ACACACAGGTTGGGATAGATGTGGAATCCCTCTCTCTCAGGGACTCAGGCCTTTCCAAAT ATATTAGGCAGACCTCTATCAATTGCAATTGACAGAAACACAAAGTAGTCTAAGCAAAAA AAACCAAACAAAACAGGACTTTATTGAAAATTCACCTTCAGGTATGGTTAGATCCAGGGG CTCCAACCTTGTAACCCAGGAACTTTTATTTTATACATCTCTTGTCTCTGCTTTTCGTTA TACTGGCTTTATTCTCAGGCAGGCTCTGAAGCAAGATGGCCCTCGGCAGGGACAGGCTCA CATTCTACCAGAATGGCAACAGCAGGAGAAAAAACATACCACTTTCAGTAACTGTAGCCA TAGTCCCAGGGCTGGCTCTCATTGGCCCAGCTTAGGCCACAGCCCACCTATGAACCAATC ATAGCAGCCAGGGAGAATGGAATATTCTGATTGGCCAGGCCTGTGTCAAAGTCCCATTCT GGGCACCAGAGGGTGGGATCCATTCCACCTGAATTAAATAGACTGAGGCAGTGGAGTGGT GGCTCCCTAAGGAAATTCAAGATGCCATTTCAAGAATGAGGGATAAACCCCAAGAGTTTC CTTACCTAAATACCTGTTTCCTTCTCTTTCAGAGGGACCTCCCAGTGAGCACTCAGGCAT ATCCCGTAACGCCATCATCTTCCTGGTTCTGGGAATCCTGGTTTTTCTGATCCTGCTGGG GATCGGGATTTATTTCTATTGGTCCAAATGTTCCCGTGAGGTCCTTTGGCACTGTCATCT GTGTCCCTCGAGTGAGCATCACCAGAGCTGCCGTAATTGAGCACCTACTACGGGCTCTGT GCTGAGTCCTTCCAGTGTGCCTCTCACTGAATCCTCACCCCACTGCCATGAGGTTTCCCC CATTTGACTGATGAGGGTGCAGAGCCAGGGAGCCTTGTTCACTGGTTCATTGATTACATT TACAAATATTATTTACAGAGTGGGAGAAGAGCGTATAGGGTCTTAATGCCATGGTAGGGA CTTTGGAATTTAATTCAGGTGATGTGGGAGTCCCTGCCAGATGGATGGAGGGTGAAATAA TGCTTAAGCCCTCAGCCTTACTCCATCTGCCTTGTTCAGGAGTGACTCCTAGGAGGAGGT GGCAGGAACTGGCACCTCTGATCCTCAGCTCTAAAAGGGTCTGATGCTTTCACACCTCAA GAGATTTGCACAGGCCGTTCCCCTGCCTGGAGCACCCTCCCATGGCTCCTTCTGGAGAAG TGTGCCAGCTCATTCTGTAATCAGAGGAACGATGCTTTGCTGAGCACTGTCTACATGCCA CTTTGTATGTATAACCCCCTCGATTTTAATTTTTAATTTTTTTTATTATTTATGTATTTA TTTATTTATTTTTGAGACAGGCTCTCACTGTCGCCCAGGCTGGAGTGCAGTGGTGCGATC TCGGCTCACTGTAGCCTTCACCTCCCAGGTTCAAGCGATTCTCATGCCTCAGCCTCCCAA GGAGCGGGGATTACAGGCACGCACTACTATGCCCAGCAATTTTTGTATTTTTAGGAGAGA CAGCGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACCCCTGGTCTCCTGTGATCCACCCG CCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCTGGCCTGTACAAT CTCCTTGAATGCCCACAACCACCCAGCAAAGTGGTTCTCCCGTGAGCCCCATGTTACAGA GGAGGAAGTATTTGCTTTGAGAGATGAAGTTACCTGCCAATGGTCAAACAGCTGGACATG GTTGTTGGGGAGAAGAAGCCAGATCTTTGACTACCAAGCTTTTCCTTCAACCACTAAACA AAGCTGCTCCCTTACAACCCAGGCGGATACTGCCTCGTCCAGGAAGCCCTCCCTGACCCC CAAGCATGAGCCAAGCATCCACTAGGCTCTCCCACTCCAGCCTTGCCCATTCTGGGTCAT CACCGTGGGGGACTTGTTTGTCATCCCCAGTGGACTGTGAGCCCCAAGATAGCAGACCTG AGGCTGTCACTGTCATGACTGTGCCCCAGGACCGCCTACCACTGGGCCGGGCATAAAAGA GGCACTCGAGGAAGTGTTTGCTGAGTGATTCAATGTGTCAGCTCCAGAGCCAGACTGCCT GTATCTGGGCCCTAAAGCTACTGCTTGATTAGTGATGTCACCATAGGCAAATAGCTTAAG CTGTATGACTCAGTTTCCTCATCTGTAAAATGGGGTGATGGTACCTAATAATACAGTAGA GCACTTAACACAGTAGGTGGCACATGGTAAGCCACATACTGAGTATGTATTTGCTATGAT TGTTATTGCTATTATTACTATTATTGTTATTATTAACATAAACTGCACAAGAGCAGGCTT TTTGTTTGTTTGTTTGTGTTTTGTTTTGAGACAAGATCTTGCTCTGTTGCCCAGACTGGA GTAGTGCAGTGATGTGATCTTGGCTCACTGCAGCCTCAACCTCCCAGGCTCAGGTGATTC TCCCACCTCAGCCTCTCGAGTAGCTGGGATTATAGGCGTGCACTCCCACGCCTGGCTAAT TTTTTATATTTTTAGTAGAGATGGAGTTTCGTTGTGTTGCCCAAGCTGGTCTCAAACTCC TAGACTCCAGCAATCCGCCCACCTCAGCCTCCCAGAGTGCTGGAATTATAGGTGTGAGCC ACCACGCCTGGCCAAGAGCAGGCATTTTTATCTGTTTTGTTCACAGCTGTGTCCCCAGCA CCTAGAATGTACCTGGCACAAAGTAGACATTCACCATTTGCTGAATAATACTACTATTTG CTAAATAAACCCCTGTTGAATAGTCTAGGAAACTGAACACAGAGAGGTTAAGTCACTTGT CCAAGTTCACACAGCTCCTAAAGGACAGAGATGGAATTTGAACCCATCCATCTGGTTCCA GAGCCAGGCTCGATATTTATGGATATTTCATAACCAAGTGAATAACTGGATGGCTAAATC CTTAGAAAGCACACCCTCCATCCCTGTCTGACACACGTGTATACCATTAAGGGAAATGGC ACCCCCATGTAATAGCAGAGGCAGAACTTGACATTTTCAGGGCCCTGACACCCAGGCATG TCTTCTTCCCATGCTTCCCAGCATTATTCCTTCCTGACGACTTCCCCTCCTATTTCCCCA GGTACAGAGCATGCCAGCGCCTCAGCTAATGGGGTAAGTGCAGTGTTGGAGCTAAGGAGG GTGTGGGGTCTGCACGAACTACAGACCAGACGTCTTCAGATGCCCACGGCCCGGCCTCAG GAGCCTGGGTCTTTTCTCCTGGTGCCTCGAGCAGCATTTCCCAACCCTTCCTGCTGGGCG GAATCCCCTGTAGAGTTTGCTAAGACGCAGCCCCAGACAGTCTGGTCTGTGATGGGGCCA GGGAATCTGCATTTTAATATCCGCTCTCTCCCCCCTGCCCCACGCCCCTTCAATTCCACC CATGGCCACACCTTGAGAAGCACTGCCCTGGCTTCCAGGGAGAGAGGAGGGGACGGGCCT GCAGTTCTTTGCACATGGGGCTTCAGTGGGAAGATGTTTGATTTTGTTCAAAAGAGCCCC AAGGCTAAAATTTGAAAACCCTCTTCTAGCATGTCTCCTATTCAGCTGTGAGCAGAGAGA ACAGCTCTTCCCAGGATCCACAGACAGAGGGCACAAGGTGACAGCGTCGGGACTGAGAGG GGAGAGAGACTGGAGCTGGCAAGGACGTGGGCCTCCAGAGTTGGACCCGACCCCAATGGA TGAAGACCCCCTCCAAAGAGACCAGCCTCCCTCCCTGTGCCAGACCTCAAAACGACGGGG GCAGGTGCAAGTTCATAGGTCTCCAAGACCACCCTCCTTTCATTTGCTAGAAGGACTCAC TAGACTCAGGAAAGCTGTTAGGCTCACAGTTACAGTTTATTACAGTAAAAGGACAGAGAT TAAGATCAGCAAAGGGAGGAGGTGCACAGCACACGTTCCACGACAGATGAGGCGACGGCT TCCATCTGCCCTCTCCCAGTGGAGCCATATAGGCAGCACCTGATTCTCACAGCAACATGT GACAACATGCAAGAAGTACTGCCAATACTGCCAACCAGAGCAGCTCACTCGAGATCTTTG TGTCCAGAGTTTTTTGTTTGTCTTGAGACAGGGTCTGGCTCTGTTGGCAGACTAGAGTAC AGTGGTGAGATCACAGTTCATTGCAGCCTTGACTTCTCAACGCCAAGTCATCCTCCCACC TCAGCCTCCTGAGTAGCTATGACTACAGGTATGTGCCACCACGTCTGGCTAATCTTTTTA TTATTTGTAAAGTCGAGGTTTCCCTGTGTTGCCCAGGCTGGTCTTGAACTCTTGGCTCCA AGTGATACTTCTGCCTTGGCCTCCCAAAGTGCTGAATTAAGCAGCTCACCATCCACACGG CTGACCTCATACATCAAGCCAATACCGTGTGGCCCAAGACCCCCACCATAAATCACATCA TTAGCATGAACCACCCAGAGTGGCCCAAGACTCCCAGATCAGCTACCAGGCAGGATATTC CAAGGGCTTAGAGATGAATGCCCAGGAGCTGAGGATAAAGGGCCCGATCTTTCTTTGGGC AAGGTTAAGCCTTTACTGCATAGCAGACCACACAGAAGGGTGTGGGCCACCAGAGAATTT TGGTAAAAATTTGGCCTCTGGCCTTGAGCTTCTAAATCTCTGTATCCGTCAGATCTCTGT GGTTACAAGAAACAGCCACTGACCCTGGTCACCAGAGGCTGCAATTCAGGCCGCAAGCAG CTGCCTGGGGGGTGTCCAAGGAGCAGAGAAAACTACTAGATGTGAACTTGAAGAAGGTTG TCAGCTGCAGCCACTTTCTGCCAGCATCTGCAGCCACTTTCTGCCAGCATCTGCAGCCAG CAAGCTGGGACTGGCAGGAAATAACCCACAAAAGAAGCAAATGCAATTTCCAACACAAGG GGGAAGGGATGCAGGGGGAGGCAGCGCTGCAGTTGCTCAGGACACGCTCCTATAGGACCA AGATGGATGCGACCCAAGACCCAGGAGGCCCAGCTGCTCAGTGCAACTGACAAGTTAAAA AGGTCTATGATCTTGAGGGCAGACAGCAGAATTCCTCTTATAAAGAAAACTGTTTGGGAA AATACGTTGAGGGAGAGAAGACCTTGGGCCAAGATGCTAAATGGGAATGCAAAGCTTGAG CTGCTCTGCAAGAGAAAATAAGCAGGACAGAGGATTTGCTCTGGACAGAGATGGAAGAGC CGGGAACAGAGAAGTGTGGGGAAGAGATAGGAACCAGCAGGATGGCAGGGGCAAAGGGCT CAAGGGTGAGGAGGCCAGTGGGACCCCACAGAGTTGGGGAGATAAAGGAACATTGGTTGC TTTGGTGGCACGTAAGCTCCTTGTCTGTCTCCAGCACCCAGAATCTCATTAAAGCTTATT TATTGTACCTCCAGCGGCTGTGTGCAATGGGGTCTTTTGTGGAAATCAAGGAGCAGACAG GTTTCATGTGTACTGTCACCACGTGGGATGGAACCAGAGGCATGGAAGCAAGACGCTAAA TGAAGAGGGCCATAAGGGCTGGGATTCCCAGGCACCTTAGGAACAGCTTGTCTTTTTTTT TTTCCTCTCCAAAAAAAATGTTTAAGGGACGGTGTCTCCTGTCACCCAGGCTGGAGTGCA ATGGCACGATCATAGCTCATTGCAGCCTCTAACTCCGGGGCTCAAGCAATCCTCCCACCT CAGCCTACCAAGTAGCTGTGACCACAGCTGCCCCTCACCATGCTAAGCTAATTTTTTTAA TTAGATAGTACATAAACGTCCCAAAATTAGAAGATAAAAAGACATGAGGGATCCATTCTA ATTTGTGTTTGGAGTGTAATGGTCCAGCTCCATTCTTCTGCACATGGATATCCAGTTTTA CACAACACTGTGAATGTAATGAATGCCACTGAATCATACACTCAAAAATAGCTAAAATGG CAAATTGTCTGTTATCTCTTTTTAACCACCATTTTTGAAAATTAATTATACCAAAAAACC ATTGAATAGTGCACTTTATTTATTTATTTATTTGTTTATTTATTTATTTATTTTAGAAAT AAGAGTCTCACTTTGTTGCCCAGGCTGGAGTGCGGTGGCGTGATCATGGCTCATTGCAGC CTCGACCTGCTGGGCTCGGGCTATCCTTCCATCTCAGCCTCCCGAGTAGCTGGGACTATA GGTGGGCGCCACCCCACCTGGCTAAATCTCTTTTTAACTTTTGTAGAGATAGGCATCTCG CTATGTTGCCTAGGCTGGGCTGGAACTCCTGGGCTCAAGTGCTCCTCCTGCCTTGGCCTC CCAAAGCGCTAGGATTACAGATGTGAGCCACCGCGCCCACCCTGAACCTTACTTTTTTTG CTCAGTTTCTGGTAATTCAGAGAATGCCTCCTGAGTTGTTCTACACCCACCTCATATTCC ATGGGAGGGCTGTACAGGGCTTTTTTAACGAGGCCTCTAAGGACAGGCATTTGTATCCTT TCCAGCCTTTCACTATTACAATGTTGTAGTGAATAACTTTACACACTGTCATTTATTTTA CTTTTTTTTTTTTTTATTTTAGAGAAAGGAATCTTGCCATCTTGCCCAGGCTGGTCTCAA ATTCCTGGGCCCAAACAATCCTCCCGCCTTGGCCTCCTAAAGTACTGGGATTTATAGGCA TAAGCCACCGTGCCTGGCCAATGCACACTGTCATTTAGCTCATGTTAACACCTGAGTGTA GGACACACTCCTGGAGGTGGAATTGCTGGGCCAAAGAGTATGTTTCTTGTCATTGTGATA GATATTGACAAATGAACCCTCACAGAAGTTGTGCTGAGTTCTGTTCCCACCAGCGACGTA GGCGATGACCTTTTTCTGGAGGGAGGGGGCATCCTTGGAGTCCACAGAGCCAGGAATGGA GAGTGGGCCCAGAATTTTGGTATAGGTGTTGTATAAACTTATAGTAAGGTTAAGAAAACC GCCACTATCCTTATCAGAGACTTGGCGGGGGGCAGGGTATGATGGAGATCATAAGGAGGC TAAAACACTCCACACCCTCCCTCTGCATTGCTCCTGCACAGGAGTCGGGAATCTTTTCAG GTTGATACGATCTCACCTTGAGGAGCTGTGAGGTCCCAGAAGCCTCTGGGTTGCAGATTG CTTGGGGTGAAAATGTCTGTGCTACTGAAATCTAACTTTTTACAAAAAATTACGGGCTGG GCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGCAGCGGGTGGATCACTT GAGGTAAGGAGTTCAAGACCAGACCATAGTGAAACCGTGTCTCTACAAAAAAAATTAGCC AGGTGTGGTGGTGCATGCTTGTAATCCCAGCTACTCAGAAGGCTGAGGTGGGAGAATCCC TTGAACCCGGGAAGTGGAGGCTGGAGTAAACCATGATCGAGTTACTGCACTCCAGCCTGG GTGACAAGAGTGAGACTCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAACTGGATTGC CTGGCTCTACTCCGGGCACAGCATGCAGGCCCAGTTCTGCTGCTCTGCTGTTTGTTCTGC TTTCCTCCACATATTGGCATCACCCTCTGGTGCCAAGATGGCTGCTGCATTCCAGGCATC ACATCCAGACTCAGACCCAGAGAAGCTGCCCATCCCTACCTGGGTGAGCCTTTGTAGGAA CGAGAAACCGCATCCAGCAGCAGAAACCTCACCCAGCAGCGTCTTTTCCGGTCTCATTCA CCAGCGCCGCCCACCGCTCAACCAATCCCTGGCCAAAAGAATGGGACCGCCTGGAAGGCT GGACCAAACAGGACCTGCCCTCTGGGGCTGGGGAGAGGCCCAGATGAAGGCTGCAGGACA GGATGGACTCCTAGACCTCTGTTACCAGCAGTGACTACCTCTGTCTGGGTGGTTGGAACA TGTTTGAATTTTATTCTAAGTACTGTCTACAAGTTCTGCAATAAACCTTGACTCTTCTTT TAATAATGCAAA OMIM ID 173850