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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5799
Official gene symbolPTPRN2
Full nameprotein tyrosine phosphatase, receptor type, N polypeptide 2
Aliases,IA-2beta,IAR,ICAAR,PTPRP,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q36
Gene position158380482 - 157331750  Map Viewer
Gene orientationminus
Gene size1048733 bp
Gene sequence
OMIM ID601698