| Entrez gene ID | | 5799 |
| Official gene symbol | | PTPRN2 |
| Full name | | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| Aliases | | ,IA-2beta,IAR,ICAAR,PTPRP, |
| Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq] |
| Location | | Chromosome: 7 Locus: 7q36 |
| Gene position | | 158380482 - 157331750 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 1048733 bp |
| Gene sequence |
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| OMIM ID | | 601698 |
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