| Entrez gene ID | | 57468 |
| Official gene symbol | | SLC12A5 |
| Full name | | solute carrier family 12 (potassium/chloride transporter), member 5 |
| Aliases | | ,KCC2,KIAA1176, |
| Gene summary | | K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] |
| Location | | Chromosome: 20 Locus: 20q13.12 |
| Gene position | | 44650329 - 44688789 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 38461 bp |
| Gene sequence |
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| OMIM ID | | 606726 |
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