| Entrez gene ID | | 5734 |
| Official gene symbol | | PTGER4 |
| Full name | | prostaglandin E receptor 4 (subtype EP4) |
| Aliases | | ,EP4,EP4R,MGC126583, |
| Gene summary | | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5p13.1 |
| Gene position | | 40680032 - 40693837 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 13806 bp |
| Gene sequence |
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| OMIM ID | | 601586 |
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