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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPS22 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID56945
Official gene symbolMRPS22
Full namemitochondrial ribosomal protein S22
Aliases,C3orf5,COXPD5,GIBT,GK002,MRP-S22,RPMS22,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q23
Gene position139062861 - 139075888  Map Viewer
Gene orientationplus
Gene size13028 bp
Gene sequence
OMIM ID605810