| Entrez gene ID | | 56945 |
| Official gene symbol | | MRPS22 |
| Full name | | mitochondrial ribosomal protein S22 |
| Aliases | | ,C3orf5,COXPD5,GIBT,GK002,MRP-S22,RPMS22, |
| Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq] |
| Location | | Chromosome: 3 Locus: 3q23 |
| Gene position | | 139062861 - 139075888 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 13028 bp |
| Gene sequence |
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| OMIM ID | | 605810 |
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