| Entrez gene ID | | 56474 |
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| Official gene symbol | | CTPS2 |
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| Full name | | CTP synthase II |
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| Aliases | | ,DKFZp686C17207,FLJ43358,MGC32997, |
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| Gene summary | | The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq] |
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| Location | | Chromosome: X Locus: Xp22 |
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| Gene position | | 16731059 - 16606122 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 124938 bp |
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| Gene sequence |
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| OMIM ID | | 300380 |
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