| Entrez gene ID | | 56262 |
| Official gene symbol | | LRRC8A |
| Full name | | leucine rich repeat containing 8 family, member A |
| Aliases | | ,FLJ10337,FLJ41617,KIAA1437,LRRC8, |
| Gene summary | | This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq] |
| Location | | Chromosome: 9 Locus: 9q34.11 |
| Gene position | | 131644391 - 131680318 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 35928 bp |
| Gene sequence |
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| OMIM ID | | 608360 |
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