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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LRRC8A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID56262
Official gene symbolLRRC8A
Full nameleucine rich repeat containing 8 family, member A
Aliases,FLJ10337,FLJ41617,KIAA1437,LRRC8,
Gene summaryThis gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.11
Gene position131644391 - 131680318  Map Viewer
Gene orientationplus
Gene size35928 bp
Gene sequence
OMIM ID608360