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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPIB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5479
Official gene symbolPPIB
Full namepeptidylprolyl isomerase B (cyclophilin B)
Aliases,CYP-S1,CYPB,MGC14109,MGC2224,OI9,SCYLP,
Gene summaryThe protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q21-q22
Gene position64455354 - 64448014  Map Viewer
Gene orientationminus
Gene size7341 bp
Gene sequence
OMIM ID123841