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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for XAF1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 54739 Official gene symbol XAF1 Full name XIAP associated factor 1 Aliases ,BIRC4BP,HSXIAPAF1,XIAPAF1, Gene summary X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM] Location Chromosome: 17   Locus: 17p13.1 Gene position 6659156 - 6678966  Map Viewer Gene orientation plus Gene size 19811 bp Gene sequence >XAF1:6262530..6282340:Length=19811 GGTAGATGCGGCTGTGACAGCAGCAAAGAATGACGGCCAAGGGCGACAGCAGGGGCTGGC CATGCTGTAAAGGGGCTTCTTGGGAGGGTCCAGCCTCAGGAATCAAGGGGAACTCCTGAG CCGAGAATTCTGAAGATCTCCTCCCTCCCTGAAGCTGTGGGCTGGGCCATCGGAAAACTT TCAGTTTTGTTTCCTTGCCTGCAAGAAACGAAACTCAACCGAAAGCCTGCAGAGAGCAGA ACATGGAAGGAGACTTCTCGGTGTGCAGGAACTGGTAAGAAAGTGCTTTCTCCAGCGGCA GACCCGGGCTGGCGAGGGAGAGACGTAGACGACATAGGGCTGTTTCTGAAGGGAGCAGAA AGTGGTTCCTGCATAAGAACACTTAGGAGGACAAGCAGCTGGAGACCGTGGGCCCCAAGG GTAGGAGGGTTTAAACTTGGTAATCTCTGGGTGGGGGTGGGCAGCATTACCTCCACTTCA CTGCAGCCCCTTTCCCCCAAATGTTAGGCTTTCTGGGACAGTTCTGAAGCCAAATAGCCC GGCCAGTGGTCCCAACTGGGCTACTCATACTTGTGAGACCTTGGGTCCTAATTTGGGGTT CTGATACTATGACCTTCACACCCATCTGTGAAAGAAAGTGTCCCACGGAGATTCTCCAGG ACTACTCTCACCCTCCTTGGAAAGGGAGCCGTGGGGCGGGGCAGGGGGGACAGAGCAGGG GGCTGGGACCACACCTCTAACGGGAGGGGGGGCGCGGAATCTGACCGATCAAAAAGCCCC ATTCTCAAAGCTCCCTACCTGTGACAGGGACCTGAGTGGACCCTCCCCAGAGAGCTTTGC TCCAGCCAGACCCTTCAAGTACTCTGGTTTCTCAACCAGCCCAGGAAGAGCAGGGGGAGA AGGGGCCAGGTCAGGCAGAGGAGAGAGAGCAGAGGAAGGGAAGATGATGCTGCCTGTGTG CCCGCTGCCTGGGCAGAAGAGGAGTGAGGCTTTGACAGTCCCTCTCGGAGCACGTCCCCT GTGCCAGGAACATGGGCATGTAACTCTTCTCGTCCCCTGGGCCTTTACGGCTACAGCCAC CCCATTTCCCTTCTCCCAAGCTGCCACAAGCAAGAGCTGATGGAAATGAAAGGAGTCATT TCTTTCTTTCTTCTTCTTTTTTTTTTTTTTTTAAGATGGAGTTTCGCTTCTTTTTGCCCA GGCTGGAGTGCCTGGAGTGCAATGGCGCGATTTCAGCTCACTGCAACCTTCATCTCTCGG GTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGTTGGGATTACAGGCGTGCACCGCC ATGCCCGGCTAATTTTGTATTGTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCT GATCTCTAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATT ACAGGCATGAGCCACCACACCCAGCCAAAAGGGGGCACTTCTTGGCAAAAAGGACGGTTA GAGAAAAATGCCCTGCCCAGGAAGTGGGAGGCTCAGAACCCTTCCTTCACTGTGGTCTCC AGGAAGAACCTCGGAGTCTCTGTGAGTTAGCGCAGGTGAACCTGAAGGCAGGGGAGACTT GGGAAGCTCTCGCTTTGGAGATTTTGGAAGTTGGCATGGCCCTGGCAGGAAGCGTGAGCC TAGCAGGGCTGCGTTCCTAACACTGTGGACCAAACAGGGGCACCAGAAAACAAGAAAAAA GATTCAAGAGAATTTGGCACTTCTCTCAAATTATTTAAATTGAAATAATTTAATTATTTA CATTATTTAAAATGAAATGTTTCATTTTAAAAACAGCCTTATAGAGGTATAATTGACCTA CAATAAACCTCACATTTTAAAGGGTAGCAATTGATAAGTTTTGGCCTAAGTTATATACAT CCATGAAACACCATCCCCGTAATTGAGATAATGAAGCTTCCTGTCACCCCAAAAGCTCCC CATGCCCCTTTGTAATTCCTCCCTCCTGCTCCTTCCCATGCCCTGCCCCAGCAATGTAAG AGCTCTGTAGATCATCCTTATTCTTATTAGATGCTGCCTCACTGTTCTGACTTTTGGACC CACACAGGGAGTGTGGGGCAGGTGGTGTCATCATCATCACATGTTCAGTGCTTAAGGCCT CTGGAGATCTAGCCCTGGGTATGAAATACAGCTCCATGTTTTATAATATGAAAATAAGTC TATTTTTCTATCCCCACACCTTGACCCTGTAGTAAAAGACATGTAGTCTCTGCCAACTTC ACCCTCCATGAGGCTTACTGCCTGCGGTTCCTGGTCCTGTGTCCGGAGTGTGAGGAGCCT GTCCCCAAGGAAACCATGGAGGAGCACTGCAAGCTTGAGCACCAGCAGGTGAGGAGGCGG CAGGGAGGATGGGGTCTGAGAGTCAAGGTGAGTGTTCAGTCCTCCCTGCAGGTGAGATGG GGTCTGAGAGTTGGGGGACGAGGGTCTAGTCCTCCCTGCAGGTGAGATGGGGTCTGGGAG TCAAGGCAAGTGTTCAGTCCTCTCTGCAGGAGAGATGGGGTCTGAGAGTCAAGGCGAGTG TTCAGTCCTCTCTGCAGGTGAGATGGGGTCTGAGAGTCAAGGCAAGTGTTCAGTCCTCTC TGCAGGTGAGATGGGGTCTGGGAGTCAAGGCGAGTGTTCAGTCCTCTCTGCAGGACAGAT GGGGTCTGAGAGTCAAGGCGAGTGTTCAGTCCTCTCTGCAGGTGAGATGGGGTCTGGGAG TCAAGGCGAGTGTTCAGTCCTCCCTGCAGGTGAGATGGGGTCTGGGAGGGGCAAGTGTTC CATCTTCCCTGCAGGAGAGATGGGGTCTGGGAGTCACAGAGTGGGTCCAGTCCTCCCTGC AGGAGAGATGGGGTCTGAGAGTTGGGGGACGAGGGTCTAGTCCTCCCTGCAGGTGAGATG GGGTCTGGGAGTCAAGGAGAGTGTTCAGTCCTCCCTGCAGGTGAGATGGGGTCTGGGAGG GGCAAGTGTTCCATCTTCCCTGCAGGAGAGATGGGATCTGGGAGTCACAGAGTGGGTCCA GTCCTCCCTGCAGGAGAGATGGGGTCTGAGAGTTGGGGGACGAGGGTCCAGTCCTCCCTG CAGGTGAGATGGGGTCTGGGAGGGGCAAGTGTTCCATCCTCCCTGCAAGAAAGAAGGGGT CTGGGAGTCAGGGAATGGCTCCAGTCCTCCCTGCAGGAGAGATGGGGTCCGGGAGTTGGG GTGAGGGCTGGGGACTTAAGGCAAGGGTCCAGTCCCCCAGGCAGAGACTCACTTGAGGGC CATGGGAAGTCATTTAGCCCCTCCACACAAAGCCCATGGAAAGGAAATGTTAATCCTGCC TTTTTCATGCTAATCTGAGTCTACCTCCAGTTTTCCTATTTCCAATCCTTTCCCTACAGG CTTATGGATCTGGCATAGGCAAGAGGTTCTGGTTTCAGGAAAGACTGGCTGTTCTCTTGA GATCTGTAAAGAGAGGATGTGAAAAAGGAAGGTCCTGGAAGGCAGTCAGATGGAGCCCTG TTTCCCGCCTTTCCATGTCCATTCCTCCTGGGGCCCCTGATCTGTCTCTCTGGAGATACT CAAGCTCAGGCAGCCGTTGCCAACTCAGACTGGTCTGACAAACACTTCTTGAACACTGGG CGGGGTGCTAGAGAGACACTGAGGTAGCCACATCGGATCCCTGCCCTCTGGGAGTTCACA GACCCAAACCCGGAACACTGTGAGCCAAAGTGGATGTGGGGCAGGCCCTGGGTGCTGGGT GGACCCACATCTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAGGTTGGGTGTACGATG TGTCAGCAGAGCATGCAGAAGTCCTCGCTGGAGTTTCATAAGGTAAGAGCCCCATGTGAT TTCTCCTTTACAGCCAAATAGACCAACCTGAGAAAAGGAGAGGAAGGGGAAACGGGAGGC CAGTAATAGAGATTTCCACCTGACCACTCTTTTCACCCCATTAGGCTTGGAGAGCAGTGG AGAACTAGCCCACCGCATAACACAGGTTCTCCTGTCCCCCAGATACTGATCAGAAGGGTT TTCCATGGTCCATGAGTCCATCAGAGCTCAGATCCCCCGAAGGCAGTCCCGCACTCTGGC CCTTCTCATCTGCTTTCTCGTATTGGCCCTAATTCCCTAGGGAGATGGGCACAAGTCCTT GATCTGCCTACAGTCAAAGAGGCCAGTGATCGGCCAGGCGCAGTGGCACACGCCTGTAAT CCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACGAGGTCAGGAGTTCGAGACCAGCCT GACCAACATGGTGAAACCCCGTCTCTACTAAAAGTACAAAAATTAGCTGGGCGTGGTGGC ACACGCCTGTGGTCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGA GGCGGAGGTTGCAGTGAGCCAAGATCAAGCCACTGCACTCCAGCCTGGGCAACACAATGA GACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAGGGCCAGTGATCATGCCCTTCCTGCTGC CTCCCACAGGCCAATGAGTGCCAGGAGCGCCCTGTTGAGTGTAAGTTCTGCAAACTGGAC ATGCAGCTCAGCAAGCTGGAGCTCCACGAGTCCTACTGTGGCAGCCGGACAGAGCTCTGC CAAGGCTGTGGCCAGTTCATCATGCACCGCATGCTCGCCCAGCACAGAGATGTCTGTCGC AGTGAACAGGCCCAGCTCGGGAAAGGTAAGCACACAAACTGGGGTGGAAGAGAGACGTTC CAAGGGCCAGAGCCTTTCCTGGATGGGATGCAAGGAAGGGAAGCTCTCAACAGGACGGAT GACAAGTGTATTTGCTGTATAGATCTCAATTCATCTGGCTATTCTAATTCTAAACCATGC CTCAGAGTGGCCTTCCTGTGTGTCTGCTGTGGCCTTCAAATGACTGGTCCAGGGAGACTA GGAGGCCGGGGCTAGAGCCTAGCTACCACAAAGTTGAGTAAAGAGGCCATGGAGAAGGCT GGGCGGGGTGGCTAATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCAC CTGAGGTTGGGAGTTCGAGACCACCTTGACCAACATGGAGAAACCCCGTCTCTACTAAAA ATACAAAATTAGCCGGGCGTGGTGGCGGACGCCTGTAGTCCCAGCTACTTGGGAGACTGA GGCAGGAGAATCACTTGAACCCGGTAGGCGGAGGTTGCAGTGAGTCGAGATCGTGCCATT GCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAGGGGGGGACCAT GGGGAGTCCTAGGAAACAGGAGGCTTTCTTTGAGCACCTCTAGCACAGTCCTAGCCTGGC AGAGATCCATTGCATCCTTTTACAGATGAGAAACCTACACACAGAATAAAGCAGGGACTT GCTAGAGGCAAAAATAAGACTGGACTCCCGCACTTCCTGGCACTGAATCTAGGGCTTTTT CCATTATCAACAATGGCCAGAAGGGAGTTAGCAATGGCTCCTGGCCTGGGGGCCTATGTA TTGGCTCCCTGGTACCATTTTATGTTCACTTGAATCACTCACCTCTTTATGAGGGTGTAT TTACTGTCACACAACCATCAGTGTGACAGATCCTTTGGTGTCTTTGCTAGTTGTTTTGGT AACATGGTAACATGGGAGAGAGCCTAAAACTCCCCAGACAGTAACCTTCTCCTGATAAAC AATCCACCCAAGGGCAAAACTGGCCAATGGAAACCTGGAAATTGTGAGAGTCATGTATAT TTCCTTCATCCCAGCATGGCTGGACGTCAACAGAATCAAACACAGTCTTCAACACAACTT CAGTGCAACACAACACAACACAACACAACACAGCTTCAACACTGTCAACAAAAATGTGTT CAACCAACACCTGGTCTGATCACAGAGTCTGAAAACTGGTGCAATGAAAGAGCACAGTCA GAATGGAGGGGGTTGGCATCCGTGGCTACAGCTCCATTCATCTCCTTAGAAACCAGTCCT GATCCAGGAAAATGTCTCTCCATTACGGTTGCTGCTGCCCTGAGTGCACATCTGTGGCCA TAAAGGAAATGATGTGGGTGATTCGGCCAAGAGTTGCCTGTGTGGTCAAGGATGCCGGCA GCGCAGGAAAGTCAAGACCAGGCAGGTCCGGGGGGCAGTTCGTGCTCATGAGCACAGGCC ATGTATGCAGTTGTGGGAGAGCTGGGCTAGCCGTTGACAAGGACAATCATTTGTGGTGTT GTTTCTCTGCTTATTCAGGGGAAAGAATTTCAGCTCCTGAAAGGGAAATCTACTGTCATT ATTGCAACCAAATGATTCCAGAAAATAAGTATTTCCACCATATGGTGAGTAGCACTTAGT AATTTTCTAATGGTGCCAATAGTTCATCCACATTCTGAAAAGTGTGATAGGAAAGGCAGA TTCTGGGCCCAATTTTACATAGCATGGATATTAAAGGGTCCCATATTTATTTTTTGCTTT GTTCCAAAAGATAGTTTAGTGACTTGCTTAGGCTAATCAAGCACACAAAAATTGGTCTTC ATTTGTGCCCAGCCCTTCAAAGGGGCTTCCCTTGCCACTCCCAACACCCCCGATCACCTC TGACCATCTCCAAACTTCATGGCCTGGACATTGCAATTTGGTCCTCAGTAGGGCCTGTCT TACTGTTTTCGGTCCCATGTGGGAGTCTTCTCTATTAGACTGTGAGCTTCCTGCAAAACT GCATGACTTTTTCCATTTTCCTGACATCAGAGCTTGGTGCAAAAAGAGGACTCTGTAGAG GCGCAGTTACGTGATTGACTGACTGACTGATTTTGCCTGGGAACACTCACAGGTTCTTCC CTCCATAGCCCCTAAGCGCCGTTTAGTGCATTGCTGTGCCAAGTTGCTCCCTTCTTTTGC ACAGAATGGAGCATTTCCCCTTTGGGAAACTTACCAAGGCTTCTCTCCAAAGAACTCTTC TCCTTCTCCTTGGGCAGAAAGTTGTTTACCTTTCTTAACACTTCAGTGCTTAAAACTACA GAATATCAAAACTAAAGAAACCATAGAGACGATCCAGCTTTTCGCTCTTTTCTTTTTCTT TTTACTATTGTGGTAAACCACGTATAATGTAAAATTTGCCATCACTATAGAGACATTTGG TACATTCACAATGTTGTGCAATCTGGTTCTAGAATATTTTCATCATTCCAAAAAGAAATC CTATACCCATTAGCAGGTACTGTACATTCCCTCATCTTCCCAGTTCCTGGCAACCACTAA TCTGCTTTCTATCTCTATGGATTTGTCTATTCTGGACACTTCACATCAGTAGACTCATAT AATATGTGGTCTTATGTAACCATCTTCTTTCACTTACCGTAACATTTTCAAGGTTTGCCC GTGTTGTAGTTGTGGCATGTGTCAGCATTTCATTCCTTTTAATGGCCTTTTCTTTTCTTT TATTTTTTTGAGACAGGGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTC GGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCGGAGT AGCTGGGGCTACAGGTGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTTTTTAGTAG AGACGGGGTTTTACCATGTTGGCCAGGCCAGTCTCAAACTCCTGACCGCAGGTTATCCGC CTTCCTCGGCCTCCCAAAGTTAATGGCCTTTTTACGGTCATCCCACATTTTGTTTCTCTA CTTGTTGGTAAACATTCGGATTGTTTCCACCTTTCAGCTCTTTGCTTTTTGAAGTGCAGT CTGTGGACCAGCTGCATGAGCATCACCTGGAATCCTGTTAGAAATGCAGAATCTCAGGCC CTCCCCCTAGAAATGCTAAATCAGAATATGCAGGGTCACATGATTTCCCAGGCATTTCAA GTCTGAGATGCGCTGCCCCAGCCACGGGATTCTCAGCCTTGGCTGTACGTGGAAATCACC TACTGACTTGTTTTCCTTAGTACTGATGTTTATTCGATCCTATAAGTGGTCCATGTGTTC TGTTTGAATGAGAAAATACTTGGTGAGCACCAAAACAAGAGTAAAGCTGACTACTTCCCT TCAAATGTCCAGCCTGGCAACCAGGGCACCTACACACTTATTTGAAGGCTACAGGGAAGT GGGGAGCTCCAATACACATGGAACTGGATTTGTGCTCAGAAACTCTGAATTTTAGTTCTG CTGTGCCCCTTACTGGCTGTGTAACCTCTCTGAGCTTCTTTCTTCTTTTGAGGAAAATGG GGATAATGGTTTATCTCCTTGTTCAGGAAAAGAAGACATCCACAACCAGCCAACACCAGA TCTATCTCCTTGGCAGCATCCACACTCACTTACTTTGCCTTCCCACCTCTTAACCATAGA GGAGCTTCCTATGTGCCTCTCTAAAGCCTATCCCCTCCTACTGGTATAATATACCCTCTC TTTTTGCCTACACAAGGTCACACAAGTTTTTTGCTACACTGCTCCAGCAATTCTCCCCTC TCTGTCCTGCAACAGAGAGAGGTTAAATGAGCTGTACACGCAGGTAACAACAAAGTCTCA CATCTCTAGGTTGTCCTAACATTTCTTACAATAACTTTTTAAAGGGGTACCACTATTGAA TATTTATATATCAATGGCCTTGCACGAAAAGAATTTTTTTTTAATTTTGAAAATTAAGGA TTGAAATCATGTATACTAGGTGGTTTTGTGGTTTTCAGTCTTTAACTTTTTATTAATATG ACCCAAAGCCAGAAAAACATGAAATACTTCTGATCCCATTTCCTATAAGCTACCATCTTG TTTCTTTGTTCCCCTCCGTAGAAAAACATTTGAGCTAGTTGTCTATAAGTAACTGCCTCC ATCTTTTCTTCTCTCATTCTTATTCCCACTCCAGTCTGGCTCTCCATTTTAACCAAATCT GCTCTTGTCAAAATCAATGACCTCTGCATTGCTAAATCCAATGCTCAGTTCTCAGTTCTC AATTTATGGGAAGCATTTACTGCTCATCACTCCCTCTTCCTCAGTGGACTTTCTCGGCTT CCAGGGTACCACACTTTCCTGGTTTTCAAGGACATTGGTGGTCTCTCATTCTCTACCTCC CCAGCCTCTTAATTTTGGGGGGCCCCAGGGCTTAGTCTCTGGTCTCTTCTCTACCTATAT TCACTGCCTTCATTATTTCATCCTACCTCCTGATTTTTAAAAATGCCATATGTAAGGCCG GGTATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGAGGATCACA AGGTCAGGAGATCGAGACCAACCTGGCTAACACAGTGAACTCTCGTCTCTACTAAAAATA CAAAAACTTAGCCGGGTGTGGTGGTGGGTGACTATAGTCCCAGCTACTCGGGAGGCTGAG GCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACGCCACTA CACTGCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAATAGATAAATAAATAAAAA TTTAAAAATTTTTTAAAAAGCCATATGTAGTCAGACACTTCCAAATTTATATCTCAGTCT GGGTTTTTCTCCCCAAACTCTAGATTTGTATATTACTATTTACTGCATCTTCACTTGAAT GCTTGATAGACATCTTAAATGTAACACATCTGAAATGGAATCCTCTCTGCCACAGCTTGG CCCATCTCAGTTGATGGCAACTCTATCTTTCCAGTTGTTCAGGCCAAAATCTCAGGTTCA CTCTCGACTTCTCTTTCCCTCCGCATTGCTACCCTGGTATGAACCATCATCTTCTCTAGC CCAGATGCTGCAGCAGTCTCCTAAACGGTCTTCCTACTTCTCACCTTGCCCCCTACAGTC TATTCTCATCACAGAGGTCAACGTGATCCCTTAAAAATACAAGTCAGATTGTTTGGCTCC TCTGTTCAGATCTCTGTACTGATTCTTGCCCCATTTTATGCAAACTCAAAACTACAGTGG CTTTAGAGATCTATGTCATCTTTGCCTCCCTTCTTATCTCATCACCTCTTTGATCTCATG TACTACTCCTGTTCAGCTCACTGGCCTCCTGATTGTTTCTTGAGCATACCATGCCTTAGG GCCTTTTCACTGGCTACTGCCTCTGGCTGGAAGCTACCTCCTCACCTTCCCCACCCTACT CCAGGAGCTAACTCTCTCACTTCTCTCAAGTCTTTGCCCAGATGGCACCTTCTCAAGGAG ATGTACCACAACAACCTATTTAAAATTGCAACTCCCTCTCCATCACATATTTACCAACCC CTTACCTTCTTCTATTATTTTTTCCATAGCATTTGCCAACTTCTAACATATTATCTAATT TACTTACTTATTATGGCCCTTGTTAATTGTCTCCCACGACCTCAGAAAAACTATAAGCCC CACTGGTCCCCTTCATGCTAACTACTCCCCAGACACAAATACTCTACTTTTGCTTTTAGC TGTTTCTTCTGGTAATCACCTTCATATGTCTAAAGCACCTTCTTATATTTTTTCCAGTTT TAGATATTACTTATTGACTCATAAGGATTTAGGAATATAGATTTCACTTTTTTATACCAC CCATCCCACACACACACCTCCAAAGTTCTTCATTTCATCCTTCCAATGTATTGATTTCAC TCATTCTGGTTAAATAAATATTCAGTATTACATTAGTATAACCATGTAAACATTATAAAT GGTTTTCCACATGAATTGTGATTATGTGTTCTTTCTCCTACAACTTTTTGTTTTACCTGG ACTTAATAATTGCTTCGGTTTTTCATTTGCTTCACTTTCTAGGTACCTATCACTAAATCA TCCCTAAAATTCTCTACCAGATCTGAAAATTCCCCTGAGTACAACTACACACATCAGATA GTCTGTCCATTTCATTTTGGGAGCATGTTATGCCCCAGGCTTGATGATTAGCTGTTGGTC TGGAATTTCTTCCACTCTCTCCACGGTTGGAGTTCTGATTCCCAAATCTCAGGTCTCATC TTTCTCTTTCTTAGGTTACTCCTTGTTTGATAGAACATATCCCCAAATAGTTTCTTGAGA AAGAAAGCATGAGAGGCAAATTTTTTAGGCCTTATATGTCTGAAAATGAAAGCTTGGGTG GCTATAGAATCTATTGACCATCTTAATCTGTTTATTAAAAATCTTATTACAATTCTGATT TGGCCACTACACACTGTATACATGTATTAGAAAATCATTCTGTATTCTATAAGTATGTAT CATTATTACTTGTCCACTAAAAATAAAAGAAATAAAATTGATTACAAAAACTTTCAAATA AATATGACAGTAGAAAGTTAATACAATAAACATTCATGTATTTACTCCCCAGATACAACA GTTGTTGTTCTAAACAAGGTGAATAAAAATAAATCTACTCTTAGATACATTACAGGTAAA AGGCAAAGGTTGATTTCTTTGAAATCAGCCGAAGAAGATTACAAGCAAAGGAATGGCAGT TAGGCTGAAAGCAAATATATCGACAGCAATAATAGAAGTGGGTATGCAGTGGAATAATCT TCAAAGTGCTAAGAGAAAATAGCTGTTAACACGTGGAAATCAAAAGTTTTCCAGGCTTGA ACTATACTTTGTTTGTTTTCTTTTTTCTAAAGTATGTTAAAGCAAATCCAAGATATCCTG TTATTTCACCATCATTCTTTAATATCTCAAAAATACAGTCATTTTCTTAATCACAATGCC TTTATCACTCTCAATGATGTTAACAATAATTTTCCCCCATCGTTTTGGGGCCTTGCATTT ACCACTCTTGTTCATTACTACTGCTGCTGCTGCTGCTGCTGCTGCTGCTTGCTTCTCCCT TGTATTCTATTGGATTGAGCAAGATTTCTTTATTCTCTTTCTTCTTTCCTACTGATTCGT CAATTTTACATTTATTTCTATCATTTCAATAGTTACCCTTAACATTTTAATATAAATACT TGACTTAATAAAGTCTAAAGTTAGTCATTATCTCTACTTTCCTTACAAATAGTATATAGA TTTGAGAACATGTTAACACTGTAACTATCTTACATGAAAATGCTGCCAGAATTTTGTTTC ATTTTGCTTTCATACTACCCCTCTTTACTGATTATTGTTGTTATTTATGTAACTCATGCC TGTTTAGATATACTCACATGTTTTTGTTTTTGCTTTTTTTCTTTCTTTCTTTCTTTTTTT TTTTGAGACAAAAGTCTCACTCTGTTGCCTGGGCTTGAGTGCAGTGGCACGATCTTGGCT CACTGCAGCCTTCGCCTCCTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCTCAAGTAGCT GGTACTACAGGTGTGTGCCACCACGTCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGC TTTTCCATGTTGGCCAAGCTGGTCTTGAACTCCTGACCTCACATAATCTGCCCACCTCGG CCTCCCAAAGTGCTAGGATTACAGGCATGAGCTACTGTGCCCGGCTGGATATACTCACAA GTTTACCCTTCTCTTTACTCACATTCTTCCTTGGATCCTAAGCTTTCCTTCTGGGTATGA TTTCTCTCTTCCTGAAATACATCTCAGTAGCTTCTTCACCAAGAACCTTGAGTAGTAAAT CTTTAGTTGCCTGAAAATAAGCTTTTTGTTTTTTGCATCCATGAATGATAGTTTAGCTGG ATATCAAAATCTAGATTAACAGCTATTTTCTCTTATCATTTTGAAGATTATTCCACTGCC ATCCCACTTCTGTTATTGCTGTTGATGTATTTTCTTCCAGCCTAATTGCCATTCCTTTGT ACGTAATCTTTATATTTGGTTGATTTCAAGATCCTCTTTGCCTTTTACCTGTAACGTGTT TAAGAGTAGTTTTATTTTTATTCATTCTGTTCAGAACAATGTACTCAAATGTGTTTGCTT TTCTCCTGCTCAGGATTTCTCTTTCCTTAATATAAAGATTTATGTCACTAATCAGGCCTG AAAATTCTCATCTATTATCTCTTTGAATTCCCAACATTCCCCAACTCTCCCACATTCTCT CAACTCTCCTTCTGGAACATAACACATGTATATTAAGCATTCTCATTCTAGCTTCATGAC TCTCTTTTTTTTCATGACTCTCCTTTTTTTTCATTTCTCTCTTTTAATCGCCTTATGTCT CTTAACCTTTCATATTTTCTCTATTTCTATCTCTTATATTCTGGGTAATTTCCTGAAATT ATCTCCAAGTTCATTCATTCTTTCTTGGCCAAATCTAATTTTCTGTTTTTAGCCCATCCA TTTAGGTTCAATACCTGCATTTTTCATGTCTAGAAGTTCAATTTATCTTTCTTTCAAATT TGCCTATTTTTGTTCTCACTACAAAAAAAAGATAGGTATGTGAAGTGATTGATATGTTAA TTAACTTGATTTAATCATCCCACAATGTATATATATATTAAAATATCACATTGTACCCCA TAAATATATAAAGTTATTATTTGTTAATTACAAATTAGAAAATTTCAAATTTACCTGTTC TGTTTTTCATGAGATGTTATTCTTTTCCCAGATTTAATCATTTTTAATTAATTTATTTTA CAGTCTCTATCCTATAGTTGCATTACCTGAACTTCTTGGAGGCTAATCTGACTACTTTTG TGTCTGTGACTCTTACTCAAGGTGGATTGCTTCCTTGTGTGTTTGTAATTTTGGATTGTG AGTTTCTATCTGGTGGGACTCTACCTATGAGGATCCTCTATGACCTATTTTGAGGCTGTT GTCCCTCCAGAGGAATTTTGTGATTGCTTCTGCCAGACATCTCAATGTTTATGTTAATTC TTCTGCTCAGGGATTCCCAGACCATGAGGCCAAAGTAAATCCTAATCCCACACACAGGAA TGGCATGGACCTGTGATTTTGAGTTTTCAGGGGCATAAGTTTTCATCTCCACACTCAAAT ACCGACCCAAGAAAGAAAAGCTTCCTTGCCACTTTCCTTTTCTCATTAGCTGATACTTTT CCTCTTACCCACCATAATTTATCCTTTAAAGTTTCCAGCTTTATGCAGGATCAATAGAGT CTTACTTCCAAATCCCCACCTGTGTGGATGGGACTTTCCTGTCATCCAAGCCCCTAGTTA CAAAGTTGACCCTACATCTCCCATAAGCAGTGTCAACTCCTGTGCTTAACCAGTCCATTT GTGCTGCTATAACAGGATGCCACAGACAGAGTAATAATAAAGAACACAAATTTATTTCGA ACAGTTCTGAAGACTGGGAAGTTCAAGATCAAGGCACCACCATTTGGTGTCTGGTGAGGG CCTTCTTGCTGCCTCCTAGCATGGTAGAAAGCAAAAGAGTAGAAGGCTGTAGCCAAATAC TTCATGAATCCTCTTTTATAAGGACCCTAATCTCATTAAAAAGGGAGGACCTTTCATGAT CTAATCACCCCCGAAGGCCCCACCTCTTAATACCATCACATTGGCAGCACCTGAATTTTG GAGGAGACACATTCAAACCATAGCAACCAGTCAGACCTTCATTCCTGGAATGCAAAATTT TCTTTCTTTCCTGCAAAGCCAGCTATTAAATTGAATGTCTGTCACATTTTATACACCATA TAAAAGTGTTTACAGTGGGAATTTCTTGTGTTATCTAGTCTACTGTATTTTCTGACCATT AAAGCTGAAGTCATTTTAAAATTTGATATATTATTCACAATTGCAGGGTAAATGTTGTCC AGACTCAGAGTTTAAGAAACACTTTCCTGTTGGAAATCCAGAAATTCTTCCTTCATCTCT TCCAAGTCAAGCTGCTGAAAATCAAACTTCCACGATGGAGAAAGATGTTCGTCCAAAGAC AAGAAGTATAAACAGATTTCCTCTTCATTCTGAAAGTTCATCAAAGAAAGCACCAAGAAG CAAAAACAAAACCTTGGATCCACTTTTGATGTCAGAGCCCAAGCCCAGGACCAGCTCCCC TAGAGGAGATAAAGCAGCCTATGACATTCTGAGGAGATGTTCTCAGTGTGGCATCCTGCT TCCCCTGCCGATCCTAAATCAACATCAGGTACTCAGCCTCTGTTCTCTGCTTACCTTTCT GGGAACCATCCGCACAGTGTCTTAAAAAAATCCAAGACCTGAAAGATGTTCACAAATGTT GTGGCTGAAAAGGCCGTTTTCTCTGACTCCCACTTCTCTGGGTGCCCAAATGCACTATCT CGTAGCACTTACCACCTGGTTTATTTGCATCACCTCCGAGAGACTGAGTCACCTTTGACT CAAGCCAGGTCTTTGAAGGTAGAGCCAGGTCCCTCTTCTCTGTGTCTCCAGCTTCTAGGC CAGGGATTGATTTGGAGCAACTGCTTCAAAACTGTTGAGTAAATGAATGAATCAGAGGAT ACCCAGTCTATCTCTCTCATGGTGTAGATATGGCACTGAGGCCCAGAGATGAGATGTCTT GGTCAAGATCCTAAGCCAGTTGGTGGTGGCTTACCTCCAGCAGATCAAGGTTTGCTTCAA GAAGATCAGGGTTTGTAGGCATCTCCCTGAATATCATGATTTTTATGTCCTAGGTTATTT TCTAGTAATAATAATAACTGGCATTAGAGGTTGTTAACCATTGTGTGCCAGTTACAATAC AGAGCTCTTTATAATCTTCATCATAAACAATAGGCATGCATTTTATCTCCATTTTACAGA TAAGGTGAAGTAGCTTTCCAAGGAGTATACAATTAGAAGGTGGCAGGATCCAGCCTGAGT CCACATGTATATAGCTCCAAAGTTTATGCTCTTAAGCTCCAGATTAAATGCCTTACTTAA AAAATTTATTTTTTTTCAAAATACATAAGTACTAGATTTTGTTGGAGCTAGTTGATATAA TATCATATAAAGAAGTATAAAAGCAAAGCTAACCCTAATTCCCCAACCCCATACCCTGAG ATACCACTTTGGACAGTCTTATGGGCATCTTTTCAAAGCTCTACCTTTGCATATACAAGC CTAAACAAGCATATACTGGGTTTTACTTGTTTCTTTTTCCACACATATTATCTTACTATA CTTTTTACTCTGCCACATGCCTTTTTCACTTAGTATATGATGCATGCTTCTTACAAAAGA CTTAGTATGCCAAAACCTTTTTTTCTAACTTCCTTGTGCATCTATGTATGCACATAAGCA TATAATTTTACAAAAATGGGTTCATTTCATATTTGCTGGGGGTGTTACTAGTGCCATTTT TCCTTGCCTCCCACAATTTGGTATATTTCCTTTCACAGTTTTCTCCATCCTTATATAACA GAGTCGCCAGATTTAGCAAATAAAAATACAGGACATTCAGTCAAATTTGAATTTCAGAGA AACAAAGAATTGTTTTTAGTGTAGGTATATTCCATGCAATGATTGTTTTGCTAAAATTAA AATTTAACCAGGACACCCTGTATTTTATTTAGCAATTTCTTATATAACCACCATACAAAC ATACACATTTGGAGTCCTGTTATATACATTTTTTCACTTTTTTTTTTTTGAACCAGTAAA GCTGCCATCTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGG CTGGAATGCAGTGGTGGGATCTCGGCTCACTGCGATCTCTGCCTCCCGGGTTCAAGCGAT TCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAGTACAGGCACCCGCCACCACACCCAGCTA ATTTTTGCATTTTAGTACAGATGGGGTTTCACCATGTTGTCCATGCTGGTCTTGAAATCC TGACCTCAGGTGATCCACCCGCTTCAGACTCCCAAAGTGCTGGAATTATAGGGCATGAGC CACCACGCCCAGCAACATTTCTTTACATCCTAATGTAAATTCAGCAATACCCAAGGAAAT CCCTACAAACAAAACAGTGTGGCTTATTTTTATTAATGGCTGCCTAAGATTCCATGGTGT GAGTGTTCTCCCATCTGTCCCTCCACCCAGTGATAGCAACAGGCCCCTGTTAAACTTTGT CGCAAGCCTCCTATACTTCTGGCTCAGTGGGCTCCTGACCTTTTCTATGCCATTACACTC CAGTCTTTGGGCAGGGCTCATGCTCTGTAACAAGGGACAGCAATATCCAGAGATATTCTA GGAGCTAGCACTTCTTACTTTAACCATATCAAACTTTTTTTATATCCATTTCTTAGGAGA AATGCCGGTGGTTAGCTTCATCAAAAGGAAAACAAGTGAGAAATTTCAGCTAGATTTGGA AAAGGAAAGGTACTACAAATTCAAAAGATTTCACTTTTAACACTGGCATTCCTGCCTACT TGCTGTGGTGGTCTTGTGAAAGGTGATGGGTTTTATTCGTTGGGCTTTAAAAGAAAAGGT TTGGCAGAACTAAAAACAAAACTCACGTATCATCTCAATAGATACAGAAAAGGCTTTTGA TAAAATTCAACTTGACTTCATGTTAAAAACCCTCAACAAACCAGGCGTCGAAGGAACATA CCTCAAAATAATAAGAGCCATCTATGACAAAACCACAGCCAACATCATACTGAATGAGCA AAAGCTGGAGCATTACTCTTGAGAAGTAGAACAAGGCACTTCAGTCCTATTCAACATAGT ACTGGAAGTCCTCGCCACAGCAATCAGGCAAGAGAAAGAAATAAAAGGCAACCAAAAAGA AAGGAAGTCGAAGTATCTCTGTTTGCAGACGATATGATTCTATATCTAGAAAACCCCATG ATCTTGGCCCAAAAGCTCCTAGATCTGATAAACAACTTCAGCTAACTTTCAGGAGACAAA ATCAATATACAAAATATGGTAGCATTTTTATACACCAACGACATCCAAGCTGAGAGCCAA ATCAAGAATGCAATCCTATTCACAATTGCCACAAAAAGAATAAAATACCTAGGAATACAG CTAACCAGGGAGATGAAAGATCTCTACAACAAAAATTACAAAACACTGCTGAAAGAAATC AGAGATGACACAAATGGAAAAACATTCCATACTTATGGATAGGAAGAATCAATATTGTTA AAATGGCCATACTACCCAAAGCAATTTATAGATTCAATGCTATTCCTATCAAACTACCAA TAACATTCTTCACAGAATCAGAAAAAAAAAGCATTAAAATTTATTTGAAACCAAAAAAGA GCCCAAAAAGCCAAAGCAATCCTAAGCAAAAAGAACAAAGCTGGAGGCATCGCATTACCC AACTTCAAACTATACTACAGGGCTACAGTAACCAAAACTGCATGATACTGGTACAAAAGC ATGGTGCTGGTACAAAAGCAGACACATAGATCAATGGAACAGAATAGAGGGCCCAGAAAT AAAGCTACACACCTACAACCATCTAATCTTTGACAAAGTTGACAAAAATACGCAATGGGG AAAGAATTCCCCATTCAGTAAGTGGTACTGGGATAACTAGCTAGCCATATGCAGAGGATT GAAACTGAACCACTTCCTTACACCATATGCAAAAATCAACTCAAGATGGATTAAAGACTT AAATGTAAAACCCCAAACTATAAAAACTCTGGAAGATAACCTAGGCAATACCATTCTGGA CATAGGAACGGAAAAAGATTTCATGACAAAGATCCCAAAAATAATTGTAACGAAAGCAAA AATTGACAAATGGGACATGATTAAACAGAATTACCATTTGACTCAGCAATCCCATTATTG GTTATATACCCAAAGGAATCTAAATCATTCTGTCATAAAGACATATATACACAAATGTTC ACGGCAGCACTATACACAATCGCAAAGTCAGGGAATCAAACTAAATGTCCATCAGTGGTA GAAAGGATAAAGAAAATGTGGTGGCAGGGAGTGGTGGCTCATGTCTGTAATCCCAGCACT TTGGGAGGCTGAGGCGGGTGGTTCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAAC ATGGAGAAACTCCGTCTCCGCTAAAAATACGAAAATTAGCCAGGCGTGGTGGCGAGCACC TGTCATCCCAGCTACTTGGGAGGCCTAGGCGTGAGAATCGCTTGAACCTGGAAGGTGGTG GTTGCAGTGAGCCGAGATCCTGCCACTGCACTCCAGCCTGGGCAACCAAGCGAGACTCTG CCTTAAAAAAAAAAAAAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCAT AAAAAAGAATGGGATCATGTCCTGTGCAGCAACGTGGATGGAGCTGGAAGCCATTATCCT AAATGAACTCACTCAGAAACAGAAAACCAAATACCACATGTTCTCACTTATAAGTAGAAG CTAAACATTGAGTACACATGGATACAAAGAAGGGAACCGCAGACACTGGGGCCTACCTGA GGTCGGAGCATGGAAGGAGGGTGAGGATCAAAAAACTACCTATCTGGTACTATGCTTTTT ATCTGGATGATGAAATAATCTGTACAACAAACCCTGGTGACATGCAATTTACCTATATAG CAAGCCTACACATGTGCCCCTGAACCTAAAAAAAAAGTTAAAAGAAAAACGTTTGGATTA TTTTCCCTCTTTCGAACAAAGACATTGGTTTGCCCAAGGACTACAAATAAACCAACGGGA AAAAAGAAAGGTTCCAGTTTTGTCTGAAAATTCTGATTAAGCCTCTGGGCCCTACAGCCT GGAGAACCTGGAGAATCCTACACCCACAGAACCCGGCTTTGTCCCCAAAGAATAAAAACA CCTCTCTAAAA OMIM ID 606717