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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PI3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5266 Official gene symbol PI3 Full name peptidase inhibitor 3, skin-derived Aliases ,ESI,MGC13613,SKALP,WAP3,WFDC14,cementoin, Gene summary This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq] Location Chromosome: 20   Locus: 20q12-q13 Gene position 43803540 - 43805185  Map Viewer Gene orientation plus Gene size 1646 bp Gene sequence >PI3:13999632..14001277:Length=1646 TTAGCCAAACACCTTCCTGACACCATGAGGGCCAGCAGCTTCTTGATCGTGGTGGTGTTC CTCATCGCTGGGACGCTGGTTCTAGAGGCAGCTGTCACGGGAGGTGAGTGAACAGGTGAC CTGCTGGGCTGGGTTGGACTAAGGGGAGACCCTCTGGGACACCCTGGGCCAGGACAGGGA GCACTTCTGAAGCAGTAGGCAGCACTGGAGCCCAGATTTCAGCTTTCTGTTCTTTGCCAT CATATTCAGAAAAAATAGGACTTTGGCTGGTGGACTCCACGTGCTTTCCACCTCAGTGAC TGAGATATCAGGACTGTTTGTGGAAGTAATGTTGGTATGTGGCCTTGGCCTCAGATGTCA ATACCTGTGCAGAATGTGCAATAAAATAATGAACTCCAGGATTTTAAACCTTGGGTGTGG ACACAGTCCCCCGTTTCTCTGCCCCATAAAAGCACTGGAGTAATCAGTACTCTAAAAGGA GGTTAAGAAACAACAAGCCTTCAGGAATCATGTTGTTTGAGGACCCCCATTTTATAAGGA GGGAACCAAAAATGTAGAAATGAGTGAGCAATTGCCAAGGTAATTCCCAGAGCCAGGATG GGGCTCAAGTCTCCTAGTATGTGGCTCAGGGTTCTTTCCTACTCCAATGCACTTCCTAAC AAATGACAATGTGTCCTCTTCACTGCTGGGTGTCACCCCAGTCTGACCACTGCTCCTGAG AGACTTGGAGTGGAGGAAGGGGGAAGAAACAAATACTCAAGGGAACTCTGGTCCAGTAGA CCACCCCAAAAAAGGAAGAGCCTTCCAAGAGTGTAGCTCCCAGAGGTGTACCTTCCCTAC TCAGGCCATGGTTTGAGGATGCTGCAGTAAGCAGTGGATGGACCCAGACCCAGAGGAAAG ACATGGCAGCTGAAGCAGAGGCTTACTGGGTATAAATGTGGGCTCGTTTCTTCTTTTAAC AGTTCCTGTTAAAGGTCAAGACACTGTCAAAGGCCGTGTTCCATTCAATGGACAAGATCC CGTTAAAGGACAAGTTTCAGTTAAAGGTCAAGATAAAGTCAAAGCGCAAGAGCCAGTCAA AGGTCCAGTCTCCACTAAGCCTGGCTCCTGCCCCATTATCTTGATCCGGTGCGCCATGTT GAATCCCCCTAACCGCTGCTTGAAAGATACTGACTGCCCAGGAATCAAGAAGTGCTGTGA AGGCTCTTGCGGGATGGCCTGTTTCGTTCCCCAGTGAGGTGAGCACTAGCTGGAGAACGA GGAGACCCCTGAAGACACAAAAGAAGGCTGAGCGGTGGGGAAGCATCCCAGGTTGGTGGG AGGGAGGTTGTGGGAGGTGACAGAAAGACTGGGAGACTGAGGGGTCTGAGAGGCTATAAC CAGAGTGCCTAGAAGGATGATCTGTCTTCCTCACTGCCTCTGAGTGCTTTGATGTGCTGA CTCTCACCTCTGATACTCTTCTCTTCCACAGAGGGAGCCGGTCCTTGCTGCACCTGTGCC GTCCCCAGAGCTACAGGCCCCATCTGGTCCTAAGTCCCTGCTGCCCTTCCCCTTCCCACA CTGTCCATTCTTCCTCCCATTCAGGATGCCCACGGCTGGAGCTGCCTCTCTCATCCACTT TCCAATAAAGAGTTCCTTCTGCTCCA OMIM ID 182257